Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials
Journal article
Edwards, J., Deenmamode, A.H.P., Griffiths, M., Arnold, O., Cooper, N.J., Wiles, J. and O'Driscoll, J. 2023. Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials. British Journal of Sports Medicine. https://doi.org/10.1136/bjsports-2022-106503
Authors | Edwards, J., Deenmamode, A.H.P., Griffiths, M., Arnold, O., Cooper, N.J., Wiles, J. and O'Driscoll, J. |
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Abstract | Objective: To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal anti-hypertensive exercise prescription practices. Design: Systematic review and network meta-analysis. Data sources: PubMed (MEDLINE), the Cochrane library and Web of Science were systematically searched. Eligibility criteria: Randomised controlled trials published between 1990 and February 2023. All relevant work reporting systolic blood pressure (sBP) and/or diastolic (dBP) reductions following an exercise intervention ≥2 weeks with an eligible non-intervention control group were included. Results: 270 randomised controlled trials were ultimately included in the final analysis, with a pooled sample size of 15,827 participants. Pairwise analyses demonstrated significant reductions in resting sBP and dBP following aerobic exercise training (-4.49/-2.53mmHg, P<0.001), dynamic resistance training (-4.55/-3.04mmHg, P<0.001), combined training (-6.04/-2.54mmHg, P<0.001), high intensity interval training (-4.08/-2.50mmHg, P<0.001) and isometric exercise training (-8.24/-4.00mmHg, P<0.001). As evidenced in the network meta-analysis, the rank order of effectiveness based on the surface under the cumulative ranking curve (SUCRA) values for sBP were isometric exercise training (SUCRA: 98.3%), combined training (75.7%), dynamic resistance training (46.1%), aerobic exercise training (40.5%) and high intensity interval training (39.4%). Secondary network meta-analyses revealed isometric wall squat and running as the most effective sub-modes for reducing sBP (90.4%) and dBP (91.3%) respectively. Conclusion: Various exercise training modes improve resting blood pressure, particularly isometric exercise. The results of this analysis should inform future exercise guideline recommendations for the prevention and treatment of arterial hypertension. |
Keywords | Exercise training mode; Blood pressure; Hypertension |
Year | 2023 |
Journal | British Journal of Sports Medicine |
Publisher | BMJ Publishing Group |
ISSN | 0306-3674 |
1473-0480 | |
Digital Object Identifier (DOI) | https://doi.org/10.1136/bjsports-2022-106503 |
Official URL | https://bjsm.bmj.com/content/early/2023/07/02/bjsports-2022-106503 |
Publication dates | |
25 Jul 2023 | |
Publication process dates | |
Accepted | 16 Jun 2023 |
Deposited | 26 Jul 2023 |
Accepted author manuscript | License |
Output status | Published |
https://repository.canterbury.ac.uk/item/951zv/exercise-training-and-resting-blood-pressure-a-large-scale-pairwise-and-network-meta-analysis-of-randomised-controlled-trials
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