Cardiac autonomic and left ventricular mechanics following high intensity interval training: a randomised cross-over controlled study.
O'Driscoll, J., Wrigth, S., Taylor, K., Coleman, D., Sharma, R. and Wiles, J. 2018. Cardiac autonomic and left ventricular mechanics following high intensity interval training: a randomised cross-over controlled study. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.00056.2018
|Authors||O'Driscoll, J., Wrigth, S., Taylor, K., Coleman, D., Sharma, R. and Wiles, J.|
Physical inactivity and sedentary behaviour is associated with increased cardiovascular disease risk. Short duration high intensity interval training (HIIT) has been shown to improve important health parameters.
The aim of the present study was to assess the combined adaptations of the cardiac autonomic nervous system and myocardial functional and mechanical parameters to HIIT. Forty physically inactive and highly sedentary males completed 2-weeks of HIIT and control period. The HIIT protocol consisted of 3x30-second maximal cycle ergometer sprints against a resistance of 7.5% body weight, interspersed with 2-minutes of active recovery. Total power spectral density (PSD) and associated low-frequency (LF) and high-frequency (HF) power spectral components of heart rate variability were recorded. Conventional and speckle tracking echocardiography recorded left ventricular (LV) structural, functional and mechanical parameters. HIIT produced a significant increase in total ln PSD and ln HF, and significant decrease in LF/HF ratio (all p<0.05) compared to the control period. HIIT produced significant improvements in LV diastolic function, including lateral E’, estimated filling pressure (E/E’ ratio), E deceleration time, and isovolumetric relaxation time (p<0.05 for all). Fractional shortening was the only conventional marker of LV systolic function to significantly improve (p<0.05). In this setting, there were significant improvements in global peak systolic strain rate, early and late diastolic strain rate and early to late diastolic strain rate ratio, as well as apical rotation, apical systolic and diastolic rotation velocity, apical radial and circumferential strain and strain rate, LV torsion and LV systolic and diastolic torsion velocity (all p<0.05). A short-term programme of HIIT was associated with a significant increase in cardiac autonomic modulation, demonstrated by a residual increase in cardiac vagal activity as well as significantly improved cardiac function and mechanics.
This study demonstrates that HIIT may be an important stimulus to reduce the health implications associated with physical inactivity and sedentary behaviour.
|Keywords||Cardiac mechanics; heart rate variability; high intensity interval training|
|Journal||Journal of Applied Physiology|
|Publisher||American Physiological Society|
|Digital Object Identifier (DOI)||https://doi.org/10.1152/japplphysiol.00056.2018|
|Online||28 Jun 2018|
|Publication process dates|
|Deposited||03 Jul 2018|
|Accepted||28 Jun 2018|
|Accepted author manuscript|
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