Identifying continence options after stroke (ICONS): a cluster randomised controlled feasibility trial.

Journal article

Thomas, L.H., Watkins, C.L., Sutton, C.J., Forshaw, D., Leathley, M.J., French, B., Burton, C., Cheater, F., Roe, B., Britt, D., Booth, J., McColl, E., The ICONS Project Team and The ICONS Patient, Public and Carer Involvement Groups 2014. Identifying continence options after stroke (ICONS): a cluster randomised controlled feasibility trial. Trials. 15 (509). https://doi.org/10.1186/1745-6215-15-509
AuthorsThomas, L.H., Watkins, C.L., Sutton, C.J., Forshaw, D., Leathley, M.J., French, B., Burton, C., Cheater, F., Roe, B., Britt, D., Booth, J., McColl, E., The ICONS Project Team and The ICONS Patient, Public and Carer Involvement Groups
Abstract

Background: Urinary incontinence (UI) affects half of patients hospitalised after stroke and is often poorly managed. Cochrane systematic reviews have shown some positive impact of conservative interventions (such as bladder training) in reducing UI, but their effectiveness has not been demonstrated with stroke patients.

Methods: We conducted a cluster randomised controlled feasibility trial of a systematic voiding programme (SVP) for the management of UI after stroke. Stroke services were randomised to receive SVP (n = 4), SVP plus supported implementation (SVP+, n = 4), or usual care (UC, n = 4). Feasibility outcomes were participant recruitment and retention. The main effectiveness outcome was presence or absence of UI at six and 12 weeks post-stroke. Additional effectiveness outcomes included were the effect of the intervention on different types of UI, continence status at discharge, UI severity, functional ability, quality of life, and death.

Results: It was possible to recruit patients (413; 164 SVP, 125 SVP+, and 124 UC) and participant retention
was acceptable (85% and 88% at six and 12 weeks, respectively). There was no suggestion of a beneficial
effect on the main outcome at six (SVP versus UC: odds ratio (OR) 0.94, 95% CI: 0.46 to 1.94; SVP+ versus UC:
OR: 0.62, 95% CI: 0.28 to 1.37) or 12 weeks (SVP versus UC: OR: 1.02, 95% CI: 0.54 to 1.93; SVP+ versus UC:
OR: 1.06, 95% CI: 0.54 to 2.09).

No secondary outcomes showed a strong suggestion of clinically meaningful improvement in SVP and/or SVP+
arms relative to UC at six or 12 weeks. However, at 12 weeks both intervention arms had higher estimated odds of continence than UC for patients with urge incontinence.

Conclusions: The trial has met feasibility outcomes of participant recruitment and retention. It was not powered to demonstrate effectiveness, but there is some evidence of a potential reduction in the odds of specific types of incontinence. A full trial should now be considered.

KeywordsCluster randomised controlled trial; Feasibility; Stroke; Urinary incontinence
Year2014
JournalTrials
Journal citation15 (509)
PublisherBioMed Central
ISSN1745-6215
Digital Object Identifier (DOI)https://doi.org/10.1186/1745-6215-15-509
Official URLhttps://doi.org/10.1186/1745-6215-15-509
Publication dates
Print23 Dec 2014
Publication process dates
Accepted09 Dec 2014
Deposited15 Jun 2020
Output statusPublished
References

1. Lawrence ES, Coshall C, Dundas R, Stewart J, Rudd AG, Howard R, Wolfe, CDA:
Estimates of the prevalence of acute stroke impairments and disability in a
multiethnic population. Stroke 2001, 32:1279–1284.
2. Kolominsky-Rabas PL, Hilz MJ, Neundoerfer B, Heuschmann PU: Impact of
urinary incontinence after stroke: results from a prospective population-based
stroke register. Neurourol Urodyn 2003, 22:322–327.
3. Williams MP, Srikanth V, Bird M, Thrift AG: Urinary symptoms and natural
history of urinary continence after first-ever stroke–a longitudinal
population-based study. Age Ageing 2012, 41:371–376.
4. Jorgensen L, Engstad T, Jacobsen BK: Self-reported urinary incontinence in
noninstitutionalized long-term stroke survivors: A population-based
study. Arch Phys Med Rehabil 2005, 86:416–420.
5. Party ISW: National Clinical Guideline for Stroke. 4th edition. London: Royal
College of Physicians; 2012.
6. Intercollegiate Stroke Working Party: National Sentinel Stroke Audit 2010.
London: Royal College of Physicians; 2011.
7. Booth J, Kumlien S, Zang Y, Gustafsson B, Tolson D: Rehabilitation nurses
practices in relation to urinary incontinence following stroke: a cross-cultural
comparison. J Clin Nurs 2009, 18:1049–1058.
8. Jordan LA, Mackey E, Coughlan K, Wyer M, Allnutt N, Middleton S: Continence
management in acute stroke: a survey of current practices in
Australia. J Adv Nurs 2011, 67:94–104.
9. Thomas LH, Cross S, Barrett J, French B, Leathley M, Sutton CJ, Watkins C:
Treatment of urinary incontinence after stroke in adults. Cochrane
Database Syst Rev 2008, (Issue 1):Art. No.: CD004462. doi:10.1002/14651858.
CD004462.pub3.
10. Eustice S, Roe B, Paterson J: Prompted voiding for the management of
urinary incontinence in adults. Cochrane Database Syst Rev 2000, (Issue 2):
Art. No.: CD002113. doi:10.1002/14651858.CD002113.
11. Dumoulin C, Hay-Smith EJC, Mac Habée-Séguin G: Pelvic floor muscle
training versus no treatment, or inactive control treatments, for urinary
incontinence in women. Cochrane Database Syst Rev 2014, (Issue 5):Art. No.:
CD005654. doi:10.1002/14651858.CD005654.pub3.
12. Wallace SA, Roe B, Williams K, Palmer M: Bladder training for urinary
incontinence in adults. Cochrane Database Syst Rev 2004, (Issue 1):Art. No.:
CD001308. doi:10.1002/14651858.CD001308.pub2.
13. Thomas LH, Watkins CL, French B, Sutton C, Forshaw D, Cheater F, Roe B,
Leathley MJ, Burton C, McColl E, Booth J: The ICONS Project Team and the
ICONS Patient, Public and Carer Involvement Groups: Study protocol:
ICONS: Identifying continence options after stroke: a randomised trial.
Trials 2011, 12:131.
14. Intercollegiate Stroke Working Party: National Sentinel Stroke Audit.
Organisational Audit 2009. London: Royal College of Physicians; 2010.
15. Goldstein M, Barnett HJM, Orgogozo JM, Sartorius N, Symon L, Vereshchagin
NV: Recommendations on stroke prevention, diagnosis, and therapy.
Report of the WHO Task Force on Stroke and Other Cerebrovascular
Disorders. Stroke 1989, 20:1407–1431.
16. Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, van
Kerrebroeck P, Victor A, Wein A: The standardisation of terminology
of lower urinary tract function: report from the Standardisation
Sub-committee of the International Continence Society. Neurourol Urodyn
2002, 21:167–178.
17. Shaw C, Matthews RJ, Perry SI, Assassa RP, Williams K, McGrother C, Dallosso H,
Jagger C, Mayne C, Clarke M, Leicestershire MRC Incontinence Study Team:
Validity and reliability of an interviewer-administered questionnaire
to measure the severity of lower urinary tract symptoms of storage
abnormality: the Leicester Urinary Symptom Questionnaire. BJU Int
2002, 90:205–215.
18. Department of Health: Attributing the Cost of Health and Social Care
Research & Development (AcoRD). London: Department of Health; 2012.
19. Martin JL, Williams KS, Abrams KR, Turner DA, Sutton AJ, Chapple C, Assassa RP,
Shaw C, Cheater F: Systematic review and evaluation of methods of
assessing urinary incontinence. Health Technol Assess 2006, 10:1–132.
20. Wyman JF, Fantl JA, McClish DK, Bump RC: Comparative efficacy of
behavioral interventions in the management of female urinary
incontinence. Continence Program for Women Research Group. Am J
Obstet Gynecol 1998, 179:999–1007.
21. Milani R, Scalambrino S, Carrera S, Quadri G, Riva D, Casolati E: A randomised
trial of bladder retraining versus oxybutynin in the treatment of idiophatic
urge syndrome: early results. In Proceedings of the International Continence
Society, 16th Annual Meeting; Sept 17–19; Boston, Massachusetts. Boston:
1986:488–490.
22. Subak LL, Quesenberry CP, Posner SF, Cattolica E, Soghikian K: The effect of
behavioral therapy on urinary incontinence: a randomized controlled
trial. Obstet Gynecol 2002, 100:72–78.
23. Lentz G, Plevnik S, Stanton SL: Vaginal cones versus bladder drill for
sensory urgency treatment. In Proceedings of the International Continence
Society (ICS), 24th Annual Meeting; Prague. ; 1994:35–36.
24. Ostaszkiewicz J, Eustice S, Roe B, Thomas LH, French B, Islam T, O’Connell B,
Cody JD: Toileting assistance programmes for the management of urinary incontinence in adults (Protocol). Cochrane Database Syst Rev
2013, CD010589.
25. O’Donnell PD: Behavioral modification for institutionalized individuals
with urinary incontinence. Urology 1998, 51(Suppl 2A):40–42.
26. Cheater FM, Baker R, Reddish S, Spiers N, Wailoo A, Gillies C, Robertson N,
Cawood C: Cluster randomized controlled trial of the effectiveness of
audit and feedback and educational outreach on improving nursing
practice and patient outcomes. [see comment]. Medical Care 2006,
44:542–551.
27. Harvey G, Loftus-Hills A, Rycroft-Malone J, Titchen A, Kitson A, McCormack B,
Seers K: Getting evidence into practice: the role and function of facilitation.
J Adv Nurs 2002, 37:577–588.
28. Seers K, Cox K, Crichton NJ, Edwards RT, Eldh AC, Estabrooks CA, Harvey G,
Hawkes C, Kitson A, Linck P, McCarthy G, McCormack B, Mockford C,
Rycroft-Malone J, Titchen A, Wallin L: FIRE (Facilitating Implementation of
Research Evidence): a study protocol. Implement Sci 2012, 7:25.
29. Stetler CB, Legro MW, Rycroft-Malone J, Bowman C, Curran G, Guihan M,
Hagedorn H, Pineros S, Wallace CM: Role of “external facilitation” in
implementation of research findings: a qualitative evaluation of
facilitation experiences in the Veterans Health Administration.
Implement Sci 2006, 1:23.
30. Loftus-Hills A, Harvey G: A Review of the Role of Facilitators in Changing
Professional Health Care Practice. Oxford: RCN Institute; 2000.
31. Bamford J, Sandercock P, Dennis M, Burn J, Warlow C: Classification and
natural history of clinically identifiable subtypes of cerebral infarction.
Lancet 1991, 337:1521–1526.
32. Collin C, Wade DT, Davies S, Horne V: The Barthel ADL Index: a reliability
study. Int Disabil Stud 1988, 10:61–63.
33. van Swieten JC, Koudstaal PJ, Visser MC, Schouten HJ, van Gijn J:
Interobserver agreement for the assessment of handicap in stroke
patients. Stroke 1988, 19:604–607.
34. Katzman R, Brown T, Fuld P, Peck A, Schechter R, Schimmel H: Validation of
a short Orientation-Memory-Concentration Test of cognitive impairment.
Am J Psychiatry 1983, 140:734–739.
35. Teasdale G, Jennett B: Assessment and prognosis of coma after head
injury. Acta Neurochir (Wien) 1976, 34:45–55.
36. Avery K, Donovan J, Peters TJ, Shaw C, Gotoh M, Abrams P: ICIQ: a brief
and robust measure for evaluating the symptoms and impact of urinary
incontinence. Neurourol Urodyn 2004, 23:322–330.
37. Sandvik H, Espuna M, Hunskaar S: Validity of the incontinence severity
index: comparison with pad-weighing tests. Int Urogynecol J Pelvic Floor
Dysfunct 2006, 17:520–524.
38. The EuroQol Group: EuroQol–a new facility for the measurement of
health-related quality of life. The EuroQol Group. Health Policy 1990,
16:199–208.
39. Counsell C, Dennis M, McDowall M, Warlow C: Predicting outcome after
acute and subacute stroke: development and validation of new
prognostic models. Stroke 2002, 33:1041–1047.
40. Patrick DL, Martin ML, Bushnell DM, Yalcin I, Wagner TH, Buesching DP:
Quality of life of women with urinary incontinence: further development
of the incontinence quality of life instrument (I-QOL). Urology 1999,
53:71–76.
41. Wagner TH, Patrick DL, Bavendam TG, Martin ML, Buesching DP: Quality of
life of persons with urinary incontinence: development of a new
measure. Urology 1996, 47:67–71.
42. Taljaard M, Donner A, Klar N: Imputation strategies for missing continuous
outcomes in cluster randomized trials. Biom J 2008, 50:329–345.
43. Barrett JA: Bladder and bowel problems after stroke. Rev Clin Gerontol
2002, 12:253–267.
44. Centre for Evidence-Based Medicine. [http://www.cebm.net/]
45. Dumoulin C, Korner-Bitensky N, Tannenbaum C: Urinary incontinence
after stroke: does rehabilitation make a difference? A systematic
review of the effectiveness of behavioral therapy. Topic Stroke Rehabil
2005, 12:66–76.
46. Wikander B, Ekelund P, Milsom I: An evaluation of multidisciplinary
intervention governed by functional independence measure (FIMSM) in
incontinent stroke patients. Scand J Rehabil Med 1998, 30:15–21.
47. Tibaek S, Gard G, Jensen R: Pelvic floor muscle training is effective in
women with urinary incontinence after stroke: a randomised, controlled
and blinded study. Neurourol Urodynamics 2005, 24:348–357.
48. Abrams P, Cardozo L, Khoury S, Wein A: Incontinence: 4th International
Consultation on Incontinence. London: Health Publications Ltd; 2009.

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Masterson-Algar, P., Williams, S., Burton, C., Arthur, C., Hoare, Z., Morrison, V., Radford, K., Seddon, D. and Elghenzai, S. 2018. Getting back to life after stroke: co-designing a peer-led coaching intervention to enable stroke survivors to rebuild a meaningful life after stroke. Disability and Rehabilitation. 42 (10), pp. 1359-1372.
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Turton, B.M., Williams, S., Burton, C.R. and Williams, L. 2018. Arts-based palliative care training, education and staff development: A scoping review. Palliative Medicine. 32 (2). https://doi.org/10.1177/0269216317712189
The PD COMM trial: a protocol for the process evaluation of a randomised trial assessing the effectiveness of two types of SLT for people with Parkinson's disease.
Masterson-Algar, P, Burton, C., Brady, M.C., Nicoll, A., Clarke, C.E., Rick, C., Hughes, M., Au, P., Smith, C.H. and Sackley, C.M. 2017. The PD COMM trial: a protocol for the process evaluation of a randomised trial assessing the effectiveness of two types of SLT for people with Parkinson's disease. Trials. 18 (397), p. 2017. https://doi.org/10.1186/s13063-017-2130-1
Managing diabetes in people with dementia: a realist review
Bunn, F., Goodman, C., Jones, P.R., Russell, B., Trivedi, D., Sinclair, A., Bayer, A., Rait, G., Rycroft-Malone, J. and Burton, C. 2017. Managing diabetes in people with dementia: a realist review. Perth, Scotland NIHR Journals Library. https://doi.org/10.3310/hta21750
Implementation and trial evidence: a plea for fore-thought
Brocklehurst, P.R., Williams, L., Burton, C., Goodwin, T. and Rycroft-Malone, J. 2017. Implementation and trial evidence: a plea for fore-thought. British Dental Journal. 222 (5), pp. 331-335. https://doi.org/10.1038/sj.bdj.2017.213
What works for whom in the management of diabetes in people living with dementia: a realist review
Bunn, F., Goodman, C., Jones, P. R., Russell, B., Trivedi, D., Sinclair, A., Bayer, A., Rait, G., Rycroft-Malone, J. and Burton, C. 2017. What works for whom in the management of diabetes in people living with dementia: a realist review. BMC Medicine. 15 (141). https://doi.org/10.1186/s12916-017-0909-2
Improving skills and care standards in the support workforce for older people: a realist synthesis of workforce development interventions
Rycroft-Malone, J., Burton, C., Williams, L., Edwards, S., Fisher, D., Hall, B., McCormack, B., Nutley, S., Seddon, D. and Williams, R. 2016. Improving skills and care standards in the support workforce for older people: a realist synthesis of workforce development interventions. National Institute of Health Research. https://doi.org/10.3310/hsdr04120
Implementing a Systematic Voiding Program for Patients With Urinary Incontinence After Stroke
French, B., Thomas, L.H., Harrison, J., Burton, C., Forshaw, D., Booth, J., Britt, D., Cheater, F.M., Roe, B. and Watkins, C.L. 2016. Implementing a Systematic Voiding Program for Patients With Urinary Incontinence After Stroke. Qualitative Health Research. 26 (10). https://doi.org/10.1177/1049732316630975
Implementing best practice in infection prevention and control. A realist evaluation of the role of intermediaries
Williams, L., Rycroft-Malone, J. and Burton, C. 2016. Implementing best practice in infection prevention and control. A realist evaluation of the role of intermediaries. International Journal of Nursing Studies. 60, pp. 156-167. https://doi.org/10.1016/j.ijnurstu.2016.04.012
Bringing critical realism to nursing practice: Roy Bhaskar's contribution
Williams, L., Rycroft-Malone, J. and Burton, C. 2016. Bringing critical realism to nursing practice: Roy Bhaskar's contribution. nursing philosophy: an international journal for healthcare professionals. 18 (2). https://doi.org/10.1111/nup.12130
Managers' use of nursing workforce planning and deployment technologies: protocol for a realist synthesis of implementation and impact
Burton, C., Rycroft-Malone, J., Williams, L., Davies, S., McBride, A., Hall, B., Rowlands, A.M. and Jones, A. 2016. Managers' use of nursing workforce planning and deployment technologies: protocol for a realist synthesis of implementation and impact. BMJ Open. 6 (8). https://doi.org/10.1136/bmjopen-2016-013645
Improving skills and care standards in the support workforce for older people: a realist synthesis of workforce development interventions
Williams, L., Rycroft-Malone, J., Burton, C., Edwards,S., Fisher, D., Hall, B., McCormack, B., Nutley, S.M., Seddon, D. and Williams, R. 2016. Improving skills and care standards in the support workforce for older people: a realist synthesis of workforce development interventions. BMJ Open. 6 (8). https://doi.org/10.1136/bmjopen-2016-011964
Strategies to prevent oral disease in dependent older people
Brocklehurst, P., Williams, L., Hoare, Z., Goodwin, T., McKenna, G., Tsakos, G., Chestnutt, I.G., Pretty, I., Wassall, R., Jerkovic-Cosic, K., Hayes, M., Watt, R.G. and Burton, C. 2016. Strategies to prevent oral disease in dependent older people. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD012402
Process evaluations in neurological rehabilitation: a mixed-evidence systematic review and recommendations for future research
Masterson-Algar, P., Burton, C. and Rycroft-Malone, J. 2016. Process evaluations in neurological rehabilitation: a mixed-evidence systematic review and recommendations for future research. BMJ Open. 6 (11). https://doi.org/10.1136/bmjopen-2016-013002
Managing diabetes in people with dementia: protocol for a realist review
Bunn, F., Goodman, C., Rycroft Malone, J., Reece Jones, P., Burton, C., Rait, G., Trivedi, D., Bayer, A. and Sinclair, A. 2016. Managing diabetes in people with dementia: protocol for a realist review. Systematic Reviews. 5 (5). https://doi.org/10.1186/s13643-015-0182-4
Collaboration and co-production knowledge in healthcare: opportunities and challenges
Rycroft-Malone, J., Burton, C.R., Bucknall , T., Graham, I.D., Hutchinson, A. and Stacey, D. 2016. Collaboration and co-production knowledge in healthcare: opportunities and challenges. International Journal of Health Policy and Management. 5 (4), pp. 221-223. https://doi.org/10.15171/IJHPM.2016.08
Collective action for implementation: a realist evaluation of organisational collaboration in healthcare
Rycroft-Malone, J., Burton, C.R., Wilkinson, J., Harvey, G., McCormack, B., Baker, R., Dopson, S., Graham, I.D., Staniszewska, S., Thompson, C., Ariss, S., Melville-Richards, L. and Williams , L. 2016. Collective action for implementation: a realist evaluation of organisational collaboration in healthcare. Implementation Science : IS. 11 (17). https://doi.org/10.1186/s13012-016-0380-z
An occupational therapy intervention for residents with stroke-related disabilities in UK care homes (OTCH): cluster randomised controlled trial with economic evaluation
Sackley, C.M., Walker, M.F., Burton, C.R., Watkins,C.L, Mant, J., Roalfe, A.K., Wheatley, K., Sheehan, B., Sharp, L., Stant, K.E., Fletcher-Smith, J., Steel, K., Barton, G.R., Irvine, L. and Peryer, G. 2016. An occupational therapy intervention for residents with stroke-related disabilities in UK care homes (OTCH): cluster randomised controlled trial with economic evaluation. Health Technology Assessment. 20 (15). https://doi.org/10.3310/hta20150
Identifying Continence OptioNs after Stroke (ICONS): an evidence synthesis, case study and exploratory cluster randomised controlled trial of the introduction of a systematic voiding programme for patients with urinary incontinence after stroke in secondary care
Thomas, L. H., French, B., Sutton, C. J., Forshaw, D., Leathley, M. J., Burton, C., Roe, B., Cheater, F. M., Booth, J., McColl, E., Carter, B., Walker, A., Brittain, K., Whiteley, G., Rodgers, H., Barrett, J. and Watkins, C. L. 2015. Identifying Continence OptioNs after Stroke (ICONS): an evidence synthesis, case study and exploratory cluster randomised controlled trial of the introduction of a systematic voiding programme for patients with urinary incontinence after stroke in secondary care. NIHR Journals Library.
Collective action for knowledge mobilisation: a realist evaluation of the collaborations for leadership in applied health research and care
Rycroft-Malone, J., Burton, C., Wilkinson, J., Harvey, G., McCormack, B., Baker, R., Dopson, S., Graham, I., Staniszewska, S., Thompson, C., Ariss, S., Melville-Richards, L. and Williams, L. 2015. Collective action for knowledge mobilisation: a realist evaluation of the collaborations for leadership in applied health research and care. UK NIHR Journals Library. https://doi.org/10.3310/hsdr03440
An untapped resource: patient and public involvement in implementation comment on "Knowledge mobilization in healthcare organizations": a view from the resource-based view of the firm
Burton, C. and Rycroft-Malone, J. 2015. An untapped resource: patient and public involvement in implementation comment on "Knowledge mobilization in healthcare organizations": a view from the resource-based view of the firm. International Journal of Health Policy and Management. 4 (12), pp. 845-847. https://doi.org/10.15171/ijhpm.2015.150
Investigating preferences for support with life after stroke: a discrete choice experiment
Burton, C., Fargher, E., Plumpton, C., Roberts, G.W, Owen, H. and Roberts, E. 2014. Investigating preferences for support with life after stroke: a discrete choice experiment. BMC Health Services Research. 14 (63). https://doi.org/10.1186/1472-6963-14-63
Evaluating a systematic voiding programme for patients with urinary incontinence after stroke in secondary care using soft systems analysis and Normalisation Process Theory: findings from the ICONS case study phase.International journal of nursing studies
Thomas, L.H, French, B., Burton, C., Sutton, C., Forshaw, D., Dickinson, H., Leathley, M.J., Britt, D., Roe, B., Cheater, F.M, Booth, J., Watkins, C.L, ICONS Project Team, ICONS Patient and Public and Carer Involvement Groups 2014. Evaluating a systematic voiding programme for patients with urinary incontinence after stroke in secondary care using soft systems analysis and Normalisation Process Theory: findings from the ICONS case study phase.International journal of nursing studies. International Journal of Nursing Studies. 51 (10), pp. 1308-1320. https://doi.org/10.1016/j.ijnurstu.2014.02.009
Improving skills and care standards in the support workforce for older people: a realist review
Rycroft-Malone, J., Burton, C., Hall, B., McCormack, B., Nutley, S., Seddon, D. and Williams, L. 2014. Improving skills and care standards in the support workforce for older people: a realist review. BMJ Open. 4 (5). https://doi.org/10.1136/bmjopen-2014-005356
Does self-efficacy influence recovery and well-being in osteoarthritis patients undergoing joint replacement? A systematic review
Magklara, E., Burton, C. and Morrison, V. 2014. Does self-efficacy influence recovery and well-being in osteoarthritis patients undergoing joint replacement? A systematic review. Clinical Rehabilitation. 28 (9). https://doi.org/10.1177/0269215514527843
Towards a programme theory for fidelity in the evaluation of complex interventions.
Masterson-Algar, P., Burton, C., Rycroft-Malone, J., Sackley, C.M. and Walker, M.F. 2014. Towards a programme theory for fidelity in the evaluation of complex interventions. Journal of Evaluation in Clinical Practice . 20 (4), pp. 445 - 452. https://doi.org/10.1111/jep.12174
Investigating the organisational impacts of quality improvement: a protocol for a realist evaluation of improvement approaches drawing on the Resource Based View of the Firm.
Burton, C., Rycroft Malone, J., Robert, G., Willson, A. and Hopkins, A. 2014. Investigating the organisational impacts of quality improvement: a protocol for a realist evaluation of improvement approaches drawing on the Resource Based View of the Firm. BMJ Open. 4:e005650. https://doi.org/10.1136/bmjopen-2014-005650
Resource based view of the firm as a theoretical lens on the organisational consequences of quality improvement.
Burton, C. and Rycroft-Malone, J. 2014. Resource based view of the firm as a theoretical lens on the organisational consequences of quality improvement. International Journal of Health Policy and Management. 3 (3), pp. 113 - 115. https://doi.org/10.15171/ijhpm.2014.74
The study protocol of: 'Initiating end of life care in stroke: clinical decision-making around prognosis'.
Burton, C., Payne, S., Turner, M., Bucknall, T., Rycroft-Malone, J., Tyrell, P., Horne, M., Ntambwe, L.I., Tyson, S., Mitchell, H., Williams, S. and Elghenzai, S. 2014. The study protocol of: 'Initiating end of life care in stroke: clinical decision-making around prognosis'. BMC Palliative Care. 13 (55). https://doi.org/10.1186/1472-684X-13-55
What is rehabilitation potential? Development of a theoretical model through the accounts of healthcare professionals working in stroke rehabilitation services
Burton, C.R., Horne, M., Woodward-Nutt, K., Bowen, A. and Tyrrell, P. 2014. What is rehabilitation potential? Development of a theoretical model through the accounts of healthcare professionals working in stroke rehabilitation services. Disability and Rehabilitation. 37 (21), pp. 1955-1960. https://doi.org/10.3109/09638288.2014.991454