Evaluation of an equilibrium phase free-breathing dynamic contrast-enhanced MRI prototype sequence compared to traditional breath-held MRI acquisition in liver oncology patients

Journal article


Hopkinson, G., Lockwood, P. and Dolbear, G. 2018. Evaluation of an equilibrium phase free-breathing dynamic contrast-enhanced MRI prototype sequence compared to traditional breath-held MRI acquisition in liver oncology patients. Radiography. https://doi.org/10.1016/j.radi.2018.01.001
AuthorsHopkinson, G., Lockwood, P. and Dolbear, G.
Abstract

Introduction: Magnetic Resonance Imaging (MRI) is a commonly used for diagnosing metastatic liver disease. When patients are unable to achieve the necessary arrested respiration required during image acquisition, image artefacts occur that affect image quality and diagnostic value. The main contribution of this study is the evaluation of a novel prototype technique that allows a specific sub-group of patients to breathe freely throughout the acquisition of dynamic contrast enhanced equilibrium phase MRI of the liver.

Methods: The study compared a traditional single phase of arrested respiration T1-weighted (T1W) fat saturated (FatSat) volumetric interpolated breath-hold sequence (VIBE) with a novel free-breathing T1W 3D Radial VIBE prototype sequence. A cohort of patients (n=30) with known hepatic metastases who demonstrated difficulty in complying with the instructions for arrested inspiration were scanned. Both sets of data were compared for diagnostic quality using a Likert scale questionnaire by specialist Oncology Radiologists (n=2).

Results: Higher scores for all image quality criteria, including the presence of artefact (2.6 + 0.57; p <0.001), lesion conspicuity (2.9 + 0.35; p <0.001) and visibility of intra-hepatic vessels (2.8 + 0.37; p <0.001) were found using the free-breathing sequence (13.5 + 1.94; p <0.001 t=13.31; df 29; p <0.001) than the breath hold phase (8.1 + 2.06), confirmed with kappa (k-0.023; p-0.050).

Conclusions: The results demonstrated a 39.5% improvement in overall image quality using the T1W 3D Radial VIBE prototype sequence, and has the potential to improve patient experience and reduce image artefacts during MRI imaging of this sub-group of patients.

KeywordsMagnetic resonance imaging; free-breathing; liver oncology; radial sequence
Year2018
JournalRadiography
PublisherElsevier
ISSN1078-8174
Digital Object Identifier (DOI)https://doi.org/10.1016/j.radi.2018.01.001
Related URLhttp://www.radiographyonline.com/
Fundernone
Publication dates
Online14 Feb 2018
Publication process dates
Deposited13 Feb 2018
Accepted03 Jan 2018
Accepted author manuscript
License
Output statusPublished
Permalink -

https://repository.canterbury.ac.uk/item/88897/evaluation-of-an-equilibrium-phase-free-breathing-dynamic-contrast-enhanced-mri-prototype-sequence-compared-to-traditional-breath-held-mri-acquisition-in-liver-oncology-patients

Download files


Accepted author manuscript
16951_Manuscript CReaTe.pdf
License: CC BY-NC-ND

  • 111
    total views
  • 203
    total downloads
  • 1
    views this month
  • 1
    downloads this month

Export as

Related outputs

Student radiographers’ knowledge and experience of lateral hip X-ray positioning: A survey
Clarke, L. and Lockwood, P. 2024. Student radiographers’ knowledge and experience of lateral hip X-ray positioning: A survey. Radiography. 30 (6). https://doi.org/10.1016/j.radi.2024.08.011
The role of imaging in the diagnosis of potential air pollution related illness: a narrative review
Abigail Taylor and Paul Lockwood 2024. The role of imaging in the diagnosis of potential air pollution related illness: a narrative review. Radiography. 30 (5), pp. 1326-1331. https://doi.org/10.1016/j.radi.2024.07.014
A survey of the NHS reporting radiographer workforce in England
Lockwood, P., Burton, C., Shaw, T. and Woznitza, N. 2024. A survey of the NHS reporting radiographer workforce in England. Radiography Open. 10 (1), pp. 1-18. https://doi.org/10.7577/radopen.5635
Comparing the standard knee X-ray exposure factor, 10 kV rule, and modified 10 kV rule techniques in digital radiography to reduce patient radiation dose without loss of image quality
Lockwood, P. and Wenman, A. 2024. Comparing the standard knee X-ray exposure factor, 10 kV rule, and modified 10 kV rule techniques in digital radiography to reduce patient radiation dose without loss of image quality. Radiography. 30 (2), pp. 574-581. https://doi.org/10.1016/j.radi.2024.01.013
Obesity bias in diagnostic radiography students: A survey of attitudes, perceptions and technical confidence
Tamburrini, N. and Lockwood, P. 2023. Obesity bias in diagnostic radiography students: A survey of attitudes, perceptions and technical confidence. Radiography. 30 (1), pp. 202-208. https://doi.org/10.1016/j.radi.2023.11.006
Care of transgender patients by diagnostic radiographers: What can be learnt from the literature
Hammond, C and Lockwood, P. 2023. Care of transgender patients by diagnostic radiographers: What can be learnt from the literature. Radiography. 30 (1), pp. 145-150. https://doi.org/10.1016/j.radi.2023.10.020
Assessing the barriers and enablers to the implementation of the diagnostic radiographer musculoskeletal X‑ray reporting service within the NHS in England: a systematic literature review
Lockwood, P., Burton, C., Woznitza, N. and Shaw, T. 2023. Assessing the barriers and enablers to the implementation of the diagnostic radiographer musculoskeletal X‑ray reporting service within the NHS in England: a systematic literature review. BMC Health Services Research. 23 (1270), pp. 1-41. https://doi.org/10.1186/s12913-023-10161-y
Impostor phenomenon traits in radiography students: findings from a UK pilot survey
Gibson, C. and Lockwood, P. 2023. Impostor phenomenon traits in radiography students: findings from a UK pilot survey . Radiography. 30 (1), pp. 61-65. https://doi.org/10.1016/j.radi.2023.10.005
Investigating the adjacent patient radiation dose received during a simulated ward chest X-ray examination
Langfield, H and Lockwood, P. 2023. Investigating the adjacent patient radiation dose received during a simulated ward chest X-ray examination. Radiography Open. 9 (1), pp. 1-14. https://doi.org/10.7577/radopen.5354
Research ethics applications: Back to basics: What you ought to know about research ethics applications
Lockwood, P. 2023. Research ethics applications: Back to basics: What you ought to know about research ethics applications. Insights into Imaging. Spring (7), pp. 39-45.
An investigation into the clinical scope of practice of MRI reporting radiographers within the United Kingdom
Mitchell, M. and Lockwood, P. 2023. An investigation into the clinical scope of practice of MRI reporting radiographers within the United Kingdom. Radiography. 29 (3), pp. 489-495. https://doi.org/10.1016/j.radi.2023.02.015
Assessing the barriers and enablers to the diagnostic radiographer X-ray reporting service within the NHS in England: A systematic literature review
Lockwood, P. 2022. Assessing the barriers and enablers to the diagnostic radiographer X-ray reporting service within the NHS in England: A systematic literature review. York University.
Lead-rubber shielding effect on radiation dose to the gonads from a bilateral hand X-ray examination
Welborn, D. and Lockwood, P. 2022. Lead-rubber shielding effect on radiation dose to the gonads from a bilateral hand X-ray examination. Radiography. 28 (2), pp. 360-365. https://doi.org/10.1016/j.radi.2021.12.013
Could posterior-anterior projection cervical spine radiographs improve image quality and dose reduction
Faulkner, R. and Lockwood, P. 2022. Could posterior-anterior projection cervical spine radiographs improve image quality and dose reduction . Radiography Open. 8 (1). https://doi.org/10.7577/radopen.5004
Diagnostic radiography students' perceptions towards communication with service users who are deaf or hearing impaired.
Nolan-Bryant, A. and Lockwood, P. 2022. Diagnostic radiography students' perceptions towards communication with service users who are deaf or hearing impaired. Radiography. 29 (1), pp. 207-214. https://doi.org/10.1016/j.radi.2022.11.008
A cross-sectional student survey of the impact of the Covid-19 lockdowns on clinical placement in England
Hinds, Z. and Lockwood, P. 2022. A cross-sectional student survey of the impact of the Covid-19 lockdowns on clinical placement in England. Radiography. 29 (1), pp. 190-199. https://doi.org/10.1016/j.radi.2022.11.006
Pre-registration UK diagnostic radiography student ability and confidence in interpretation of chest X-rays
Lockwood, P. and Khan, A. 2021. Pre-registration UK diagnostic radiography student ability and confidence in interpretation of chest X-rays. Radiography Open. 7 (1), pp. 1-13. https://doi.org/10.7577/radopen.4529
Efficacy, utility, and validity in Computed Tomography head reporting by radiographers
Lockwood, P. 2021. Efficacy, utility, and validity in Computed Tomography head reporting by radiographers. PhD Thesis Canterbury Christ Church University School of Allied and Public Health Professions
COVID-19: A literature review of the impact on diagnostic radiography students
Astirbadi, D. and Lockwood, P. 2021. COVID-19: A literature review of the impact on diagnostic radiography students. Radiography. https://doi.org/10.1016/j.radi.2021.09.009
Multi-professional image interpretation: performance in preliminary clinical evaluation of appendicular radiographs
Lockwood, P. and Pittock, L. 2019. Multi-professional image interpretation: performance in preliminary clinical evaluation of appendicular radiographs. Radiography. https://doi.org/10.1016/j.radi.2019.04.013
Computed tomography head and facial bones review of a 2,700 year old Egyptian mummy
Lockwood, P., Elliott, J., Nelson, A. and Harris, S. 2019. Computed tomography head and facial bones review of a 2,700 year old Egyptian mummy . BJR Case Reports. https://doi.org/10.1259/bjrcr.20190076
Visual function assessment of diagnostic radiography students
Lockwood, P. and Blackman, A. 2019. Visual function assessment of diagnostic radiography students. Radiography. https://doi.org/10.1016/j.radi.2019.10.012
An evaluation of CT head reporting radiographers' scope of practice within the United Kingdom
Lockwood, P. 2019. An evaluation of CT head reporting radiographers' scope of practice within the United Kingdom. Radiography. 26 (2), pp. 102-109. https://doi.org/10.1016/j.radi.2019.09.001
Image Interpretation by radiographers in brain, spine and knee MRI examinations: Findings from an accredited postgraduate module
Lockwood, P. and Dolbear, G. 2018. Image Interpretation by radiographers in brain, spine and knee MRI examinations: Findings from an accredited postgraduate module. Radiography. https://doi.org/10.1016/j.radi.2018.05.009
Nuclear medicine image interpretation by radiographers: findings of an accredited postgraduate module
Lockwood, P. and Dolbear, G. 2018. Nuclear medicine image interpretation by radiographers: findings of an accredited postgraduate module. Radiography. https://doi.org/10.1016/j.radi.2018.11.007
CT Sinus and facial bones reporting by radiographers: findings of an accredited postgraduate programme
Lockwood, P. 2017. CT Sinus and facial bones reporting by radiographers: findings of an accredited postgraduate programme. Dentomaxillofacial Radiology. 46 (4). https://doi.org/10.1259/dmfr.20160440
Exploring variation and trends in adherence to national occupational standards for reporting radiographers
Lockwood, P. 2017. Exploring variation and trends in adherence to national occupational standards for reporting radiographers. Journal of Social Science & Allied Health Professions. 1 (1), pp. 20-27.
Observer performance in Computed Tomography head reporting
Lockwood, P. 2017. Observer performance in Computed Tomography head reporting. Journal of Medical Imaging and Radiation Sciences. 48 (1), pp. 22-29. https://doi.org/10.1016/j.jmir.2016.08.001
Exploring the benefits of magnetic resonance imaging reporting by radiographers: A UK perspective
Lockwood, P. 2016. Exploring the benefits of magnetic resonance imaging reporting by radiographers: A UK perspective. Journal of Medical Imaging and Radiation Sciences. 47 (2). https://doi.org/10.1016/j.jmir.2015.12.083
An economic evaluation of introducing a skills mix approach to CT head reporting in clinical practice.
Lockwood, P. 2016. An economic evaluation of introducing a skills mix approach to CT head reporting in clinical practice. Radiography. https://doi.org/10.1016/j.radi.2015.09.004
Intraorbital foreign body detection and localisation by radiographers: a preliminary JAFROC observer performance study
Lockwood, P., Pittock, L., Lockwood, C., Jeffery, C. and Piper, K. 2015. Intraorbital foreign body detection and localisation by radiographers: a preliminary JAFROC observer performance study. Radiography. 2015, pp. 1-5. https://doi.org/10.1016/j.radi.2015.06.005
Out of the comfort zone (Part 2)
Lockwood, P. 2013. Out of the comfort zone (Part 2).
AFROC analysis of reporting radiographer’s performance in CT head interpretation
Lockwood, P. and Piper, K. 2015. AFROC analysis of reporting radiographer’s performance in CT head interpretation. Radiography. 21 (3), pp. e90-e95. https://doi.org/10.1016/j.radi.2015.04.001
Out of the comfort zone (Part 1)
Lockwood, P. 2013. Out of the comfort zone (Part 1).
Origins of the Reporting Radiographer
Lockwood, P. 2013. Origins of the Reporting Radiographer.
Patient safety and quality improvement: Iatrogenic venous air embolism in diagnostic imaging
Lockwood, P. and Breen, W. 2013. Patient safety and quality improvement: Iatrogenic venous air embolism in diagnostic imaging.
CT head reporting by radiographers: Findings of an accredited postgraduate programme
Lockwood, P. and Piper, K. 2013. CT head reporting by radiographers: Findings of an accredited postgraduate programme.
CT skull base & calvarium normal variant pitfalls
Lockwood, P. 2013. CT skull base & calvarium normal variant pitfalls.
CT head reporting by radiographers: results of an accredited postgraduate programme
Lockwood, P., Piper, K. and Pittock, L. 2015. CT head reporting by radiographers: results of an accredited postgraduate programme. Radiography. 21 (3), pp. e85-e89. https://doi.org/10.1016/j.radi.2014.12.001