Kent and Medway Medical School (KMMS)


Latest research outputs

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Reverse atrial remodeling in heart failure with recovered ejection fraction
Yuxi Sun, Xuefu Chen, Yanli Zhang, Yao Yu, Xinxin Zhang, Jinping Si, Zijie Ding, Yunlong Xia, Gary Tse and Ying Liu 2023. Reverse atrial remodeling in heart failure with recovered ejection fraction. Journal of the American Heart Association. 12, p. e026891. https://doi.org/10.1161/JAHA.122.026891

Journal article

The association between neutrophil-lymphocyte ratio and variability with new-onset dementia: A population-based cohort study
Chou, Oscar Hou In, Zhou, Jiandong, Li, Lifang, Chan, Jeffrey Shi Kai, Satti, Danish Iltaf, Chou, Vanessa Hou Cheng, Wong, Wing Tak, Lee, Sharen, Cheung, Bernard Man Yung, Tse, Gary, Chang, Carlin and Liu, Tong 2023. The association between neutrophil-lymphocyte ratio and variability with new-onset dementia: A population-based cohort study. Journal of Alzheimer's Disease. 94 (2), pp. 547-557. https://doi.org/10.3233/jad-220111

Journal article

Long-term prognostic impact of cardiovascular comorbidities in patients with prostate cancer receiving androgen deprivation therapy: A population-based competing risk analysis.
Chan, J., Lee, Yan Hiu Athena, Hui, Jeremy Man Ho, Liu, Kang, Dee, Edward Christopher, Ng, Kenrick, Liu, T., Tse, Gary and Ng, Chi Fai 2023. Long-term prognostic impact of cardiovascular comorbidities in patients with prostate cancer receiving androgen deprivation therapy: A population-based competing risk analysis. International Journal of Cancer. https://doi.org/10.1002/ijc.34557

Journal article

Combination of SVI/S′ and diagnostic scores for heart failure with preserved ejection fraction
Mu, Guanyu, Wang, Weiding, Liu, Changle, Xie, Juan, Zhang, Hao, Zhang, Xiaowei, Che, Jingjin, Tse, Gary, Liu, T., Li, Guangping, Fu, Huaying and Chen, K. 2023. Combination of SVI/S′ and diagnostic scores for heart failure with preserved ejection fraction. Clinical and Experimental Pharmacology and Physiology. https://doi.org/10.1111/1440-1681.13782

Journal article

'We do not rush to the hospital for ordinary wounds (suḷu tuvāla)': A qualitative study on the early clinical manifestations of cutaneous leishmaniasis and associated health behaviours in rural Sri Lanka.
Gunasekara, Sonali Dinushika, Wickramasinghe, Nuwan Darshana, Agampodi, S., Fernando, Manoj Sanjeewa, Weerakoon, Kosala Gayan, Liyanage, Chandani, Dikomitis, Lisa and Agampodi, Thilini Chanchala 2023. 'We do not rush to the hospital for ordinary wounds (suḷu tuvāla)': A qualitative study on the early clinical manifestations of cutaneous leishmaniasis and associated health behaviours in rural Sri Lanka. PLoS Neglected Tropical Diseases. 17 (5), p. e0010939. https://doi.org/10.1371/journal.pntd.0010939

Journal article

Lower risks of new-onset acute pancreatitis and pancreatic cancer in sodium glucose cotransporter 2 (SGLT2) inhibitors compared to dipeptidyl peptidase-4 (DPP4) inhibitors: A propensity score-matched study with competing risk analysis
Tse, G. 2023. Lower risks of new-onset acute pancreatitis and pancreatic cancer in sodium glucose cotransporter 2 (SGLT2) inhibitors compared to dipeptidyl peptidase-4 (DPP4) inhibitors: A propensity score-matched study with competing risk analysis. Diabetes Epidemiology and Management. 9, p. 100115. https://doi.org/10.1016/j.deman.2022.100115

Journal article

Sodium‐glucose cotransporter 2 inhibitors versus dipeptidyl peptidase 4 inhibitors on new‐onset overall cancer in Type 2 diabetes mellitus: A population‐based study
Chung, Cheuk To, Lakhani, Ishan, Chou, Oscar Hou In, Lee, Teddy Tai Loy, Dee, Christopher, Ng, Kendrick, Wong, Wing Tak, Liu, T., Lee, Sharen, Zhang, Qingpeng, Cheung, Bernard Man Yung, Tse, Gary and Zhou, Jiandong 2023. Sodium‐glucose cotransporter 2 inhibitors versus dipeptidyl peptidase 4 inhibitors on new‐onset overall cancer in Type 2 diabetes mellitus: A population‐based study. Cancer Medicine. https://doi.org/10.1002/cam4.5927

Journal article

The role of electrophysiological study in the risk stratification of Brugada Syndrome
Bazoukis, George, Chung, Cheuk To, Vassiliou, Vassilios S, Sfairopoulos, Dimitrios, Lee, Sharen, Papadatos, Stamatis S, Korantzopoulos, Panagiotis, Saplaouras, Athanasios, Letsas, Konstantinos P, Liu, Tong and Tse, Gary 2023. The role of electrophysiological study in the risk stratification of Brugada Syndrome. Cardiology in Review. https://doi.org/10.1097/CRD.0000000000000561

Journal article

Metformin use and mortality in Asian, diabetic patients with prostate cancer on androgen deprivation therapy: A population-based study
Yan Hiu Athena Lee, Jeremy Man Ho Hui, Jeffrey Shi Kai Chan, Kang Liu, Edward C. Dee, Kenrick Ng, Pias Tang and Tse, G. 2023. Metformin use and mortality in Asian, diabetic patients with prostate cancer on androgen deprivation therapy: A population-based study. The Prostate. 83 (1), pp. 119-127. https://doi.org/10.1002/pros.24443

Journal article

Predictive value of neutrophil-to-lymphocyte ratio for atrial fibrillation and stroke in type 2 diabetes mellitus: The Hong Kong Diabetes Study
Carlin Chang, Jiandong Zhou, Oscar Hou In Chou, Justin Chan, Keith Sai Kit Leung, Teddy Tai Loy Lee, Wing Tak Wong, Abraham Ka Chung Wai, Tong Liu, Qingpeng Zhang, Sharen Lee and Tse, G. 2023. Predictive value of neutrophil-to-lymphocyte ratio for atrial fibrillation and stroke in type 2 diabetes mellitus: The Hong Kong Diabetes Study. Endocrinology, Diabetes & Metabolism. https://doi.org/10.1002/edm2.397

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Socioeconomic deprivation and prognostic outcomes in acute coronary syndrome: A meta-analysis using multidimensional socioeconomic status indices.
Anand, Vickram Vijay, Zhe, Ethan Lee Cheng, Chin, Yip Han, Goh, Rachel Sze Jen, Lin, Chaoxing, Kueh, Martin Tze Wah, Chong, Bryan, Kong, Gwyneth, Tay, Phoebe Wen Lin, Dalakoti, Mayank, Muthiah, Mark, Dimitriadis, Georgios K, Wang, Jiong-Wei, Mehta, Anurag, Foo, Roger, Tse, Gary, Figtree, Gemma A, Loh, Poay Huan, Chan, Mark Y, Mamas, Mamas A and Chew, Nicholas W S 2023. Socioeconomic deprivation and prognostic outcomes in acute coronary syndrome: A meta-analysis using multidimensional socioeconomic status indices. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2023.04.042

Journal article

Long-term cardiovascular risks of Gonadotropin-releasing hormone agonists and antagonists: A population-based cohort study
Chan, J S K, Lee, Y H A, Hui, J M H, Liu, K, Dee, E C, Ng, K, Tang, P, Tse, G and Ng, C F 2023. Long-term cardiovascular risks of Gonadotropin-releasing hormone agonists and antagonists: A population-based cohort study. Clinical Oncology (Royal College of Radiologists (Great Britain)). 35 (6), pp. e376-e383. https://doi.org/10.1016/j.clon.2023.03.014

Journal article

Association between sick sinus syndrome and atrial fibrillation: A systematic review and meta-analysis.
Liu, Ying, Zheng, Yi, Tse, Gary, Bazoukis, George, Letsas, Konstantinos, Goudis, Christos, Korantzopoulos, Panagiotis, Li, Guangping and Liu, Tong 2023. Association between sick sinus syndrome and atrial fibrillation: A systematic review and meta-analysis. International Journal of Cardiology. 381, pp. 20-36. https://doi.org/10.1016/j.ijcard.2023.03.066

Journal article

Do loneliness and social exclusion breed paranoia? An experience sampling investigation across the psychosis continuum.
Bell, Victoria, Velthorst, Eva, Almansa, Jorge, Myin-Germeys, Inez, Shergill, Sukhi and Fett, Anne-Kathrin 2023. Do loneliness and social exclusion breed paranoia? An experience sampling investigation across the psychosis continuum. Schizophrenia Research: Cognition. 33, p. 100282. https://doi.org/10.1016/j.scog.2023.100282

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Comparing sodium-glucose cotransporter 2 inhibitors and dipeptidyl peptidase-4 inhibitors on new-onset depression: a propensity score-matched study in Hong Kong.
Mui, Jonathan V, Li, Lifang, Chou, O., Azfar, Nida, Lee, Athena, Hui, Jeremy, Lee, Sharen, Tse, Gary and Zhou, Jiandong 2023. Comparing sodium-glucose cotransporter 2 inhibitors and dipeptidyl peptidase-4 inhibitors on new-onset depression: a propensity score-matched study in Hong Kong. Acta Diabetologica. https://doi.org/10.1007/s00592-023-02063-6

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Resveratrol activation of SIRT1/MFN2 can improve mitochondria function, alleviating doxorubicin‐induced myocardial injury
Zhang, Q., Zhang, Y., Xie, Bingxin, Liu, Daiqi, Wang, Yueying, Zhou, Zandong, Zhang, Yue, King, Emma, Tse, Gary and Liu, T. 2023. Resveratrol activation of SIRT1/MFN2 can improve mitochondria function, alleviating doxorubicin‐induced myocardial injury. Cancer Innovation. 2 (4), pp. 253-264. https://doi.org/10.1002/cai2.64

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Long-term atherosclerotic cardiovascular disease risk in patients with cancer: a population-based study.
Yang, Ling, Zhang, Nan, Yue, Qing, Song, Wenhua, Zheng, Yi, Huang, Shan, Qiu, Jiuchun, Tse, Gary, Li, Guangping, Wu, Shouling and Liu, Tong 2023. Long-term atherosclerotic cardiovascular disease risk in patients with cancer: a population-based study. Current Problems in Cardiology. https://doi.org/10.1016/j.cpcardiol.2023.101693

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Arrhythmias beyond atrial fibrillation detection using smartwatches: A systematic review
Pay, Levent, Yumurtaş, Ahmet Çağdaş, Satti, Danish Iltaf, Hui, Jeremy Man Ho, Chan, Jeffrey Shi Kai, Mahalwar, Gauranga, Lee, Yan Hiu Athena, Tezen, Ozan, Birdal, Oğuzhan, Inan, Duygu, Özkan, Eyup, Tse, Gary and Çinier, Göksel 2023. Arrhythmias beyond atrial fibrillation detection using smartwatches: A systematic review. Anatolian Journal of Cardiology. 27 (3), pp. 126-131. https://doi.org/10.14744/AnatolJCardiol.2023.2799

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Application of artificial intelligence in the diagnosis of sleep apnea
Bazoukis, George, Bollepalli, Sandeep Chandra, Chung, Cheuk To, Li, Xinmu, Tse, Gary, Bartley, Bethany L, Batool-Anwar, Salma, Quan, Stuart F and Armoundas, Antonis A 2023. Application of artificial intelligence in the diagnosis of sleep apnea. Journal of Clinical Sleep Medicine. 19 (7), pp. 1337-1363. https://doi.org/10.5664/jcsm.10532

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Association between immune checkpoint inhibitors and myocardial infarction in Asians: A population‐based self‐controlled case series
Chan, J., Tang, Pias, Lee, Teddy Tai Loy, Chou, Oscar Hou In, Lee, Y., Li, Guoliang, Leung, Fung Ping, Wong, Wing Tak, Liu, T. and Tse, Gary 2023. Association between immune checkpoint inhibitors and myocardial infarction in Asians: A population‐based self‐controlled case series. Cancer Medicine. 12 (8), pp. 9541-9546. https://doi.org/10.1002/cam4.5729

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The functions of self‐harm in young people and their perspectives about future general practitioner‐led care: A qualitative study
Mughal, F., Chew‐Graham, Carolyn A., Babatunde, Opeyemi O., Saunders, Benjamin, Meki, Aula and Dikomitis, Lisa 2023. The functions of self‐harm in young people and their perspectives about future general practitioner‐led care: A qualitative study. Health Expectations. 26 (3), pp. 1180-1188. https://doi.org/10.1111/hex.13733

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Automatic detection of cognitive impairment with virtual reality
Mannan, Farzana A, Porffy, Lilla A, Joyce, Dan W, Shergill, Sukhwinder S and Celiktutan, O. 2023. Automatic detection of cognitive impairment with virtual reality. Sensors. 23 (2), p. 1026. https://doi.org/10.3390/s23021026

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Influenza and pneumococcal vaccine prescription for adults during COVID-19 first wave in three regions of Argentina.
Matta, María Gabriela, Pulido, Laura, Herrera-Paz, Juan José, Picco, José M, Wolff, Sebastian, Tse, Gary and Garcia-Zamora, Sebastian 2023. Influenza and pneumococcal vaccine prescription for adults during COVID-19 first wave in three regions of Argentina. Vaccine. 41 (9), pp. 1541-1544. https://doi.org/10.1016/j.vaccine.2023.01.056

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Radiotherapy-induced malfunctions of cardiac implantable electronic devices: a meta-analysis
Xu, Beizheng, Wang, Yueying, Tse, Gary, Chen, Jiayi, Li, Guangping, Korantzopoulos, Panagiotis and Liu, Tong 2023. Radiotherapy-induced malfunctions of cardiac implantable electronic devices: a meta-analysis. Heart Rhythm. 20 (5), pp. 689-698. https://doi.org/10.1016/j.hrthm.2023.01.024

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Lower risks of incident colorectal cancer in SGLT2i users compared to DPP4i users: A propensity score-matched study with competing risk analysis.
Chan, Raymond Ngai Chiu, Chan, Robert Ngai Fung, Chou, Oscar Hou In, Tse, Gary and Lee, Sharen 2023. Lower risks of incident colorectal cancer in SGLT2i users compared to DPP4i users: A propensity score-matched study with competing risk analysis. European journal of internal medicine. https://doi.org/S0953-6205(23)00026-2

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Effectiveness and safety of transcatheter aortic valve replacement in elderly people with severe aortic stenosis with different types of heart failure.
Dong, Mei, Wang, Lizhen, Tse, Gary, Dai, Tao, Wang, Lihong, Xiao, Zhicheng, Liu, Tong and Ren, Faxin 2023. Effectiveness and safety of transcatheter aortic valve replacement in elderly people with severe aortic stenosis with different types of heart failure. BMC Cardiovascular Disorders. 23 (1), p. 34. https://doi.org/10.1186/s12872-023-03048-7

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Risk of diabetes mellitus among users of immune checkpoint inhibitors: A population‐based cohort study
Chan, J., Lee, Sharen, Kong, Dicken, Lakhani, I., Ng, Kenrick, Dee, E., Tang, Pias, Lee, Y., Satti, Danish Iltaf, Wong, Wing Tak, Liu, T. and Tse, Gary 2023. Risk of diabetes mellitus among users of immune checkpoint inhibitors: A population‐based cohort study. Cancer Medicine. 12 (7), pp. 8144-8153. https://doi.org/10.1002/cam4.5616

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Association of proteinuria and risk of incident atrial fibrillation in the general population: A prospective study of Kailuan study participants
Li, Jie, Wang, Yueying, Qi, Wenwei, Zhang, Nan, Tse, Gary, Li, G., Wu, Shouling and Liu, Tong 2023. Association of proteinuria and risk of incident atrial fibrillation in the general population: A prospective study of Kailuan study participants. Pacing and Clinical Electrophysiology. 46 (6), pp. 526-534. https://doi.org/10.1111/pace.14658

Journal article

Neuroimaging glutamatergic mechanisms differentiating antipsychotic treatment-response
Mouchlianitis, Elias D, Vanes, Lucy D, Tracy, Derek K, Fett, Anne-Katherin, Joyce, Daniel and Shergill, Sukhi S 2023. Neuroimaging glutamatergic mechanisms differentiating antipsychotic treatment-response. Scientific Reports. 13 (1), p. 8938. https://doi.org/10.1038/s41598-022-26702-0

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Cognitive bias modification for paranoia (CBM-pa): a randomised controlled feasibility study in patients with distressing paranoid beliefs.
Yiend, Jenny, Lam, C., Schmidt, Nora, Crane, Bryony, Heslin, Margaret, Kabir, Thomas, McGuire, Philip, Meek, Christopher, Mouchlianitis, Elias, Peters, Emmanuelle, Stahl, Daniel, Trotta, Antonella and Shergill, Sukhwinder 2022. Cognitive bias modification for paranoia (CBM-pa): a randomised controlled feasibility study in patients with distressing paranoid beliefs. Psychological Medicine. https://doi.org/10.1017/S0033291722001520

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Why care about integrated care? Part 3. Weighing sunlight: delivering integration in practice and measuring success
Tracy, D. K., Hanson, K., Underwood, B. R. and Shergill, S. 2022. Why care about integrated care? Part 3. Weighing sunlight: delivering integration in practice and measuring success. BJPsych Advances. 29 (1), pp. 31-40. https://doi.org/10.1192/bja.2022.26

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Constrictive pericarditis–a cloak camouflaging lymphoma
Delanthabettu Venugopala, Nikhil Victor Dsouza, Vishak Acharya, Maneesh Rai, Chaithra Gowthuvalli Venkataramana and Stergios Boussios 2022. Constrictive pericarditis–a cloak camouflaging lymphoma. Hematology Reports. 15 (1), pp. 166-171. https://doi.org/10.3390/hematolrep15010017

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Recommendations on patient-facing websites regarding diagnostic imaging for low back, knee, and shoulder pain: A scoping review
Andrew Cuff, Thomas Jesson, Gillian Yeowell, Lisa Dikomitis, Nadine E. Foster and Chris Littlewood 2022. Recommendations on patient-facing websites regarding diagnostic imaging for low back, knee, and shoulder pain: A scoping review. PEC Innovation. 1. https://doi.org/10.1016/j.pecinn.2022.100040

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The experiences and needs of supporting individuals of young people who self-harm: A systematic review and thematic synthesis
Faraz Mughal, M. Isabela Troya, Lisa Dikomitis, Stephanie Tierney, Nadia Corp, Nicola Evans, Ellen Townsend and Carolyn A. Chew-Graham 2022. The experiences and needs of supporting individuals of young people who self-harm: A systematic review and thematic synthesis. eClinicalMedicine. 48, p. 101437. https://doi.org/10.1016/j.eclinm.2022.101437

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Sickle cell disease in Bahia, Brazil: the social production of health policies and institutional neglect
Mota, C., Dikomitis, L. and Trad, L. A. B. 2022. Sickle cell disease in Bahia, Brazil: the social production of health policies and institutional neglect. Societies. 12 (4), p. 108. https://doi.org/10.3390/soc12040108

Journal article

Update on the pathophysiology of cluster headache: Imaging and neuropeptide studies
Buture, A., Boland, J. W., Dikomitis, L. and Ahmed, F. 2022. Update on the pathophysiology of cluster headache: Imaging and neuropeptide studies. Journal of Pain Research. 12, pp. 269-281. https://doi.org/10.2147/JPR.S175312

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The importance of pro-social processing, and ameliorating dysfunction in schizophrenia. An FMRI study of oxytocin
Shergill, S., Rebekah Wigton, Derek K. Tracy, Tess M. Verneuil, Michaela Johns, Thomas White, Panayiota G. Michalopoulou, Bruno Averbeck and Sukhwinder Shergill 2022. The importance of pro-social processing, and ameliorating dysfunction in schizophrenia. An FMRI study of oxytocin. Schizophrenia Research: Cognition. 27. https://doi.org/10.1016/j.scog.2021.100221

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Adverse Cardiovascular Complications following prescription of programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors: a propensity-score matched Cohort Study with competing risk analysis
Jiandong Zhou, Sharen Lee, Ishan Lakhani, Lei Yang, Tong Liu, Yuhui Zhang, Yunlong Xia, Wing Tak Wong, Kelvin King Hei Bao, Ian Chi Kei Wong, Gary Tse and Qingpeng Zhang 2022. Adverse Cardiovascular Complications following prescription of programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors: a propensity-score matched Cohort Study with competing risk analysis. Cardio-oncology (London, England). https://doi.org/10.1186/s40959-021-00128-5

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Clinical characteristics, risk factors and outcomes of cancer patients with COVID-19: A population-based study
Jiandong Zhou, Ishan Lakhani, Oscar Chou, Keith Sai Kit Leung, Teddy Tai Loy Lee, Michelle Vangi Wong, Zhen Li, Abraham Ka Chung Wai, Carlin Chang, Ian Chi Kei Wong, Qingpeng Zhang, Gary Tse and Bernard Man Yung Cheung 2022. Clinical characteristics, risk factors and outcomes of cancer patients with COVID-19: A population-based study. Cancer Medicine. 12 (1), pp. 287-296. https://doi.org/10.1002/cam4.4888

Journal article

NADPH oxidase mediates oxidative stress and ventricular remodeling through SIRT3/FOXO3a pathway in diabetic mice
Jiuchun Qiu, Daiqi Liu, Pengsha Li, Lingling Zhou, Lu Zhou, Xing Liu, Yue Zhang, Meng Yuan, Gary Tse, Guangping Li and Tong Liu 2022. NADPH oxidase mediates oxidative stress and ventricular remodeling through SIRT3/FOXO3a pathway in diabetic mice. Antioxidants. 11 (9), p. 1745. https://doi.org/10.3390/antiox11091745

Journal article

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