Kent and Medway Medical School (KMMS)


Latest research outputs

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The effect of training intensity on implicit learning rates in schizophrenia
Natasza D. Orlov, Jessica Sanderson, Syed Ali Muqtadir, Anastasia K. Kalpakidou, Panayiota G. Michalopoulou, Jie Lu and Sukhi S. Shergill 2021. The effect of training intensity on implicit learning rates in schizophrenia. Scientific Reports. 11 (6511). https://doi.org/10.1038/s41598-021-85686-5

Journal article

Development of a multivariable prediction model for severe COVID-19 disease: a population-based study from Hong Kong
Jiandong Zhou, Sharen Lee, Xiansong Wang, Yi Li, William Ka Kei Wu, Tong Liu, Zhidong Cao, Daniel Dajun Zeng, Keith Sai Kit Leung, Abraham Ka Chung Wai, Ian Chi Kei Wong, Bernard Man Yung Cheung, Qingpeng Zhang and Gary Tse 2021. Development of a multivariable prediction model for severe COVID-19 disease: a population-based study from Hong Kong. NPJ Digital Medicine. https://doi.org/10.1038/s41746-021-00433-4

Journal article

Prevalence of osteoarthritis in lower middle- and low-income countries: a systematic review and meta-analysis
Ismail Yahaya, Tanya Wright, Opeyemi O. Babatunde, Nadia Corp, Toby Helliwell, Lisa Dikomitis and Christian D. Mallen 2021. Prevalence of osteoarthritis in lower middle- and low-income countries: a systematic review and meta-analysis. Rheumatology International. 41, pp. 1221-1231. https://doi.org/10.1007/s00296-021-04838-y

Journal article

Preliminary evidence for the phosphodiesterase type-4 inhibitor, roflumilast, in ameliorating cognitive flexibility deficits in patients with schizophrenia
Nicholas R Livingston, Peter CT Hawkins, James Gilleen, Rong Ye, Lorena Valdearenas, Sukhi Shergill and Mitul A Mehta 2021. Preliminary evidence for the phosphodiesterase type-4 inhibitor, roflumilast, in ameliorating cognitive flexibility deficits in patients with schizophrenia. Journal of Psychopharmacology. 35 (9). https://doi.org/10.1177/02698811211000778

Journal article

Glycemic and lipid variability for predicting complications and mortality in diabetes mellitus using machine learning
Sharen Lee, Jiandong Zhou, Wing Tak Wong, Tong Liu, William K. K. Wu, Ian Chi Kei Wong, Qingpeng Zhang and Gary Tse 2021. Glycemic and lipid variability for predicting complications and mortality in diabetes mellitus using machine learning. BMC Endocrine Disorders. 21 (94). https://doi.org/10.1186/s12902-021-00751-4

Journal article

Renal protective effects and mechanisms of the angiotensin receptor-neprilysin inhibitor LCZ696 in mice with cardiorenal syndrome
Ying Li, Li Kang, Kai Rong, Yue Zhang, Ya Suo, Meng Yua, Qiankun Bao, Shuai Shao, Gary Tse, Rong Li, Tong Liu and Guangping Li 2021. Renal protective effects and mechanisms of the angiotensin receptor-neprilysin inhibitor LCZ696 in mice with cardiorenal syndrome. Life Sciences. 280, p. 119692. https://doi.org//10.1016/j.lfs.2021.119692

Journal article

Development of a predictive risk model for all-cause mortality in patients with diabetes in Hong Kong
Sharen Lee, Jiandong Zhou, Keith Sai Kit Leung, William Ka Kei Wu, Wing Tak Wong, Tong Liu, Ian Chi Kei Wong, Kamalan Jeevaratnam, Qingpeng Zhang and Gary Tse 2021. Development of a predictive risk model for all-cause mortality in patients with diabetes in Hong Kong. BMJ Open Diabetes Research and Care. 2021 (9), p. e001950. https://doi.org/10.1136/bmjdrc-2020-001950

Journal article

Relationship between angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and COVID-19 incidence or severe disease
Tse, Gary, Zhou, Jiandong, Lee, Sharen, Wong, Wing Tak, Li, Xintao, Liu, Tonga, Cao, Zhidong, Zeng, Daniel Dajun, Wai, Abraham K.C., Wong, Ian Chi Keih, Cheung, Bernard Man Yungi and Zhang, Qingpengb 2021. Relationship between angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and COVID-19 incidence or severe disease. Journal of Hypertension. 39 (8), pp. 1717-1724. https://doi.org/10.1097/HJH.0000000000002866

Journal article

Contextual perception under active inference
Berk Mirza, M., Cullen, M., Parr, T., Shergill, S. and Moran, R. 2021. Contextual perception under active inference. Scientific Reports. 11 (16223). https://doi.org/s41598-021-95510-9

Journal article

Pandemic pandemonium and primary care networks: Experiences of establishing primary care placements in a new medical school
Neden, C., Popoola, A. and West, J. 2021. Pandemic pandemonium and primary care networks: Experiences of establishing primary care placements in a new medical school.

Conference keynote

Dilemmas and solutions- experiences of a national Family Medicine applied knowledge licensing test during a pandemic
Elfes,C., Denney, M. L., Blow, C., Cartwright-Terry, R. and Neden, C. 2021. Dilemmas and solutions- experiences of a national Family Medicine applied knowledge licensing test during a pandemic.

Conference keynote

Paediatric/young versus adult patients with long QT syndrome
Sharen Lee, Jiandong Zhou, Kamalan Jeevaratnam, Wing Tak Wong, Ian Chi Kei Wong, Chloe Mak, Ngai Shing Mok, Tong Liu, Qingpeng Zhang and Gary Tse 2021. Paediatric/young versus adult patients with long QT syndrome. Open Heart. 2021 (8), p. e001671. https://doi.org/10.1136/openhrt-2021-001671

Journal article

Experiences of general practice care for self-harm: A qualitative study of young people's perspectives
Mughal, F., Dikomitis, L., Babtunde, O.O. and Chew-Graham, C. A. 2021. Experiences of general practice care for self-harm: A qualitative study of young people's perspectives. British Journal of General Practice (BJGP). 71 (711), pp. 3744-e752. https://doi.org/10.3399/BJGP.2021.0091

Journal article

A novel cardiovascular magnetic resonance risk score for predicting mortality following surgical aortic valve replacement
Vassilios S. Vassiliou, Menelaos Pavlou, Tamir Malley, Brian P. Halliday, Vasiliki Tsampasian, Claire E. Raphael, Gary Tse, Miguel Silva Vieira, Dominique Auger, Russell Everett, Calvin Chin, Francisco Alpendurada, John Pepper, Dudley J. Pennell, David E. Newby, Andrew Jabbour, Marc R. Dweck and Sanjay K. Prasad 2021. A novel cardiovascular magnetic resonance risk score for predicting mortality following surgical aortic valve replacement. Scientific Reports. https://doi.org/10.1038/s41598-021-99788-7

Journal article

Outcomes in treatment-resistant schizophrenia: symptoms, function and clozapine plasma concentrations
Shergill, S., Amir Krivoy, Eromona Whiskey, Henrietta Webb-Wilson, Dan Joyce, Derek K. Tracy, Fiona Gaughran, James H. MacCabe and Sukhwinder S. Shergill 2021. Outcomes in treatment-resistant schizophrenia: symptoms, function and clozapine plasma concentrations. Therapeutic Advances in Psychopharmacology. 11. https://doi.org/10.1177/20451253211037179

Journal article

Effect of sodium-glucose cotransporter-2 inhibitors on cardiac remodelling: a systematic review and meta-analysis
Nan Zhang, Yueying Wang, Gary Tse, Panagiotis Korantzopoulos, Konstantinos P Letsas, Qingpeng Zhang, Guangping Li, Gregory Y H Lip and Tong Liu 2021. Effect of sodium-glucose cotransporter-2 inhibitors on cardiac remodelling: a systematic review and meta-analysis. European Journal of Preventive Cardiology. 28 (17), pp. 1961-1973. https://doi.org/10.1093/eurjpc/zwab173

Journal article

Insights into the role of matrix metalloproteinases in precancerous conditions and in colorectal cancer
Zahra Pezeshkian, Stefania Nobili, Noshad Peyravian, Bahador Shojaee, Haniye Nazari, Hiva Soleimani, Hamid Asadzadeh-Aghdaei, Maziar Ashrafian Bonab, Ehsan Nazemalhosseini-Mojarad and Enrico Mini 2021. Insights into the role of matrix metalloproteinases in precancerous conditions and in colorectal cancer. Cancers. 13 (24), p. 6226. https://doi.org/2072-6694/13/24/6226

Journal article

Effect of vitamin D supplementation on outcomes in people with early psychosis
Fiona Gaughran, Dominic Stringer, Gabriella Wojewodka, Sabine Landau, Shubulade Smith, Poonam Gardner-Sood, David Taylor, Harriet Jordan, Eromona Whiskey, Amir Krivoy, Simone Ciufolini, Brendon Stubbs, Cecilia Casetta, Julie Williams, Susan Moore, Lauren Allen, Shanaya Rathod, Andrew Boardman, Rehab Khalifa, Mudasir Firdosi, Philip McGuire, Michael Berk and John McGrath 2021. Effect of vitamin D supplementation on outcomes in people with early psychosis. JAMA Network Open. 4 (12), p. e2140858. https://doi.org/10.1001/jamanetworkopen.2021.40858

Journal article

Systematic review of renal denervation for the management of cardiac arrhythmias
Nakulan Nantha Kumar, Kuda Nyatsuro, Shiraz Ahmad, Ibrahim T. Fazmin, Khalil Saadeh, Tse, G. and Kamalan Jeevaratnam 2021. Systematic review of renal denervation for the management of cardiac arrhythmias. Clincial Research in Cardiology. (111), pp. 971-993.

Journal article

How medical students in the United Kingdom think: About anthropology, for example
Dikomitis, L. 2021. How medical students in the United Kingdom think: About anthropology, for example. in: Martinez, I. and Wiedman, D. W. (ed.) Anthropology in Medical Education: Sustaining Engagement and Impact Cham Springer. pp. 91-113

Book chapter

New approaches to antipsychotic medication adherence – safety, tolerability and acceptability
Taub, Sharon, Krivoy, Amir, Whiskey, Eromona and Shergill, Sukhi S. 2021. New approaches to antipsychotic medication adherence – safety, tolerability and acceptability. Expert Opinion on Drug Safety. 21 (4), pp. 517-524. https://doi.org/10.1080/14740338.2021.1983540

Journal article

Metformin accelerates zebrafish heart regeneration by inducing autophagy.
Xie, F., Xu, Shisan, Lu, Yingying, Wong, Kin Fung, Sun, Lei, Hasan, K., Ma, A., Tse, G., Manno, S., Tian, L., Yue, J. and Cheng, S. 2021. Metformin accelerates zebrafish heart regeneration by inducing autophagy. NPJ Regenerative Medicine. 6 (1), p. 62. https://doi.org/10.1038/s41536-021-00172-w

Journal article

Hip fractures risks in edoxaban versus warfarin users: A propensity score-matched population-based cohort study with competing risk analyses
Zhou, Jiandong, Lee, Sharen, Liu, Xuejin, Iltaf Satti, Danish, Tai Loy Lee, Teddy, Hou In Chou, Oscar, Chang, Carlin, Roever, Leonardo, Tak Wong, Wing, Ka Chung Wai, Abraham, Liu, Tong, Zhang, Qingpeng and Tse, Gary 2021. Hip fractures risks in edoxaban versus warfarin users: A propensity score-matched population-based cohort study with competing risk analyses. Bone. 156, p. 116303. https://doi.org/S8756-3282(21)00469-5

Journal article

A systematic review of TMS and neurophysiological biometrics in patients with schizophrenia
di Hou, Meng, Santoro, Viviana, Biondi, Andrea, Shergill, Sukhi S and Premoli, Isabella 2021. A systematic review of TMS and neurophysiological biometrics in patients with schizophrenia. Journal of psychiatry & neuroscience : JPN. 46 (6), pp. E675-E701. https://doi.org/10.1503/jpn.210006

Journal article

Fragmented QRS is independently predictive of long-term adverse clinical outcomes in Asian patients hospitalized for heart failure: A retrospective cohort study
Chan, Jeffrey Shi Kai, Zhou, Jiandong, Lee, Sharen, Li, Andrew, Tan, Martin, Leung, Keith Sai Kit, Jeevaratnam, Kamalan, Liu, Tong, Roever, Leonardo, Liu, Ying, Tse, Gary and Zhang, Qingpeng 2021. Fragmented QRS is independently predictive of long-term adverse clinical outcomes in Asian patients hospitalized for heart failure: A retrospective cohort study. Frontiers in Cardiovascular Medicine. 8, p. 738417. https://doi.org/10.3389/fcvm.2021.738417

Journal article

Effect of angiotensin receptor neprilysin inhibitors on left atrial remodeling and prognosis in heart failure
Sun, Yuxi, Song, Shuang, Zhang, Yanli, Mo, Wenqiong, Zhang, Xinxin, Wang, Ning, Xia, Yunlong, Tse, Gary and Liu, Ying 2021. Effect of angiotensin receptor neprilysin inhibitors on left atrial remodeling and prognosis in heart failure. ESC Heart Failure. 9 (1), pp. 667-675. https://doi.org/10.1002/ehf2.13691

Journal article

Predictive value of HFA-PEFF score in patients with heart failure with preserved ejection fraction
Sun, Yuxi, Si, Jinping, Li, Jiaxin, Dai, Mengyuan, King, Emma, Zhang, Xinxin, Zhang, Yanli, Xia, Yunlong, Tse, Gary and Liu, Ying 2021. Predictive value of HFA-PEFF score in patients with heart failure with preserved ejection fraction. Frontiers in Cardiovascular Medicine. 8, p. 656536. https://doi.org/10.3389/fcvm.2021.656536

Journal article

Soluble suppression of tumorigenicity 2 (sST2) for predicting disease severity or mortality outcomes in cardiovascular diseases: A systematic review and meta-analysis
Ip, Christina, Luk, King Sum, Yuen, Vincent Lok Cheung, Chiang, Lorraine, Chan, Ching Ki, Ho, Kevin, Gong, Mengqi, Lee, Teddy Tai Loy, Leung, Keith Sai Kit, Roever, Leonardo, Bazoukis, George, Lampropoulos, Konstantinos, Li, Ka Hou Christien, Tse, Gary, Liu, Tong and International Health Informatics Study (IHIS) Network 2021. Soluble suppression of tumorigenicity 2 (sST2) for predicting disease severity or mortality outcomes in cardiovascular diseases: A systematic review and meta-analysis . International journal of cardiology. Heart & vasculature. 37, p. 100887. https://doi.org/10.1016/j.ijcha.2021.100887

Journal article

Gender-specific clinical risk scores incorporating blood pressure variability for predicting incident dementia
Zhou, Jiandong, Lee, Sharen, Wong, Wing Tak, Waleed, Khalid Bin, Leung, K., Lee, Teddy Tai Loy, Wai, Abraham Ka Chung, Liu, Tong, Chang, Carlin, Cheung, Bernard Man Yung, Zhang, Q. and Tse, G. 2021. Gender-specific clinical risk scores incorporating blood pressure variability for predicting incident dementia. Journal of the American Medical Informatics Association : JAMIA. 29 (2), pp. 335-347. https://doi.org/10.1093/jamia/ocab173

Journal article

Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors vs. Dipeptidyl Peptidase-4 (DPP4) inhibitors for new-onset dementia: A propensity score-matched population-based study with competing risk analysis
Mui, Jonathan V, Zhou, Jiandong, Lee, Sharen, Leung, Keith Sai Kit, Lee, Teddy Tai Loy, Chou, Oscar Hou In, Tsang, Shek Long, Wai, Abraham Ka Chung, Liu, Tong, Wong, Wing Tak, Chang, Carlin, Tse, Gary and Zhang, Qingpeng 2021. Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors vs. Dipeptidyl Peptidase-4 (DPP4) inhibitors for new-onset dementia: A propensity score-matched population-based study with competing risk analysis. Frontiers in Cardiovascular Medicine. 8, p. 747620. https://doi.org/10.3389/fcvm.2021.747620

Journal article

Distinct features of probands with early repolarization and Brugada Syndromes carrying SCN5A pathogenic variants
Zhang, Zhong-He, Barajas-Martínez, Hector, Xia, Hao, Li, Bian, Capra, John A, Clatot, Jerome, Chen, Gan-Xiao, Chen, Xiu, Yang, Bo, Jiang, Hong, Tse, Gary, Aizawa, Yoshiyasu, Gollob, Michael H, Scheinman, Melvin, Antzelevitch, Charles and Hu, Dan 2021. Distinct features of probands with early repolarization and Brugada Syndromes carrying SCN5A pathogenic variants. Journal of the American College of Cardiology. 78 (16), pp. 1603-1617. https://doi.org/S0735-1097(21)06008-3

Journal article

Characteristics and outcomes of heart failure with recovered left ventricular ejection fraction
Zhang, Xinxin, Sun, Yuxi, Zhang, Yanli, Chen, Feifei, Dai, Mengyuan, Si, Jinping, Yang, Jing, Li, Xiao, Li, Jiaxin, Xia, Yunlong, Tse, G. and Liu, Ying 2021. Characteristics and outcomes of heart failure with recovered left ventricular ejection fraction. ESC Heart Failure. 8 (6), pp. 5383-5391. https://doi.org/10.1002/ehf2.13630

Journal article

A national survey of UK healthcare professionals regarding their knowledge, experiences and training needs of assistive technology (AT)​
Morris, R., Hatzidimitriadou, E., Manship, S., Stein, M., Parkin, C., Achille-Fauveau, S. and Laval, D. 2021. A national survey of UK healthcare professionals regarding their knowledge, experiences and training needs of assistive technology (AT)​.

Conference or workshop item

Atrial cardiomyopathy: An emerging cause of the embolic stroke of undetermined source
Ning, Yuye, Tse, G., Luo, Guogang and Li, Guoliang 2021. Atrial cardiomyopathy: An emerging cause of the embolic stroke of undetermined source. Frontiers in Cardiovascular Medicine. 8, p. 674612. https://doi.org/10.3389/fcvm.2021.674612

Journal article

Heart failure with midrange ejection fraction: Prior left ventricular ejection fraction and prognosis
Zhang, Xinxin, Sun, Yuxi, Zhang, Yanli, Chen, Feifei, Zhang, Shuyuan, He, Hongyan, Song, Shuang, Tse, Gary and Liu, Ying 2021. Heart failure with midrange ejection fraction: Prior left ventricular ejection fraction and prognosis. Frontiers in Cardiovascular Medicine. 8, p. 697221. https://doi.org/10.3389/fcvm.2021.697221

Journal article

Ventricular tachyarrhythmia risk in paediatric/young vs. adult Brugada Syndrome patients: A territory-wide study
Lee, Sharen, Wong, Wing Tak, Wong, Ian Chi Kei, Mak, Chloe, Mok, Ngai Shing, Liu, Tong and Tse, Gary 2021. Ventricular tachyarrhythmia risk in paediatric/young vs. adult Brugada Syndrome patients: A territory-wide study. Frontiers in Cardiovascular Medicine. 8, p. 671666. https://doi.org/10.3389/fcvm.2021.671666

Journal article

Cardiac abnormalities after induction of endoplasmic reticulum stress are associated with mitochondrial dysfunction and connexin43 expression
He, Jinli, Gong, Mengqi, Wang, Zaojia, Liu, Daiqi, Xie, Bingxin, Luo, C., Li, Guangping, Tse, Gary and Liu, T. 2021. Cardiac abnormalities after induction of endoplasmic reticulum stress are associated with mitochondrial dysfunction and connexin43 expression. Clinical and Experimental Pharmacology and Physiology. 48 (10), pp. 1371-1381. https://doi.org/10.1111/1440-1681.13541

Journal article

Aducanumab for Alzheimer’s disease: the never‐ending story that nurses should know
Petch, J. and Bressington, D. 2021. Aducanumab for Alzheimer’s disease: the never‐ending story that nurses should know. Nursing Open. 8 (4), pp. 1524-1526. https://doi.org/10.1002/nop2.878

Journal article

The association between blood pressure variability and hip or vertebral fracture risk: A population-based study
Zhou, Jiandong, Li, Helen, Chang, Carlin, Wu, William K.K., Wang, Xiansong, Liu, Tong, Cheung, Bernard Man Yung, Zhang, Qingpeng, Lee, Sharen and Tse, Gary 2021. The association between blood pressure variability and hip or vertebral fracture risk: A population-based study. Bone. 150, p. 1160115. https://doi.org/10.1016/j.bone.2021.116015

Journal article

Social polarization and ghettoization: social and policy-driven causes
Keys, C. 2021. Social polarization and ghettoization: social and policy-driven causes. in: United Nations Encyclopedia of Sustainable Development Goals Springer.

Book chapter

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