Kent and Medway Medical School (KMMS)


Latest research outputs

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Mexiletine: Antiarrhythmic mechanisms, emerging clinical applications and mortality
Olleik, Farah, Kamareddine, Mohammed Hussein, Spears, Jenna, Tse, Gary, Liu, Tong and Yan, G. 2023. Mexiletine: Antiarrhythmic mechanisms, emerging clinical applications and mortality. Pacing and Clinical Electrophysiology. https://doi.org/10.1111/pace.14846

Journal article

The safety of digital mental health interventions: Systematic review and recommendations
Taher, R., Hsu, C., Hampshire, C., Fialho, C., Heaysman, C., Stahl, D., Shergill, S. and Yiend, J. 2023. The safety of digital mental health interventions: Systematic review and recommendations. JMIR Mental Health. 10, p. e47433. https://doi.org/10.2196/47433

Journal article

Association of late potentials with fatal arrhythmic events in patients with Brugada syndrome—A meta-analysis
Bazoukis, George, Letsas, Konstantinos P., Liu, Tong, Tse, Gary and Alsheikh-Ali, Alawi 2023. Association of late potentials with fatal arrhythmic events in patients with Brugada syndrome—A meta-analysis. Cardiology in Review. 32 (4), pp. 334-337. https://doi.org/10.1097/crd.0000000000000511

Journal article

A-294 duplicate testing of samples suspected of SARS-CoV-2 infection could prevent misdiagnosis of Covid-19
Sánchez-Sánchez, J, Thapa, G, Mylona, A and Vuono, R 2023. A-294 duplicate testing of samples suspected of SARS-CoV-2 infection could prevent misdiagnosis of Covid-19. Clinical Chemistry. 69 (Supplement_1). https://doi.org/10.1093/clinchem/hvad097.259

Journal article

Secular trends of health care resource utilization and costs between Brugada syndrome and congenital long QT syndrome: A territory-wide study
Lee, Sharen, Chung, Cheuk To Skylar, Radford, Danny, Chou, Oscar Hou In, Lee, Teddy Tai Loy, Ng, Zita Man Wai, Roever, Leonardo, Rajan, Rajesh, Bazoukis, George, Letsas, Konstantinos P., Zeng, Shaoying, Liu, Fang Zhou, Wong, Wing Tak, Liu, Tong and Tse, Gary 2023. Secular trends of health care resource utilization and costs between Brugada syndrome and congenital long QT syndrome: A territory-wide study. Clinical Cardiology. https://doi.org/10.1002/clc.24102

Journal article

Clinical and non-clinical cardiovascular disease associated pathologies in Parkinson's disease
Bonn Lee, Charlotte Edling, Shiraz Ahmad, Fiona E. N. LeBeau, Gary Tse and Kamalan Jeevaratnam 2023. Clinical and non-clinical cardiovascular disease associated pathologies in Parkinson's disease. International Journal of Molecular Sciences. 24 (16), p. 12601.

Journal article

Associations between modifiable risk factors and frailty: a Mendelian randomisation study
Nan Zhang, Ziheng Jia, Tianshu Gu, Yi Zheng, Yunpeng Zhang, Wenhua Song, Ziliang Chen, Guangping Li, Gary Tse and Tong Liu 2023. Associations between modifiable risk factors and frailty: a Mendelian randomisation study. Journal of Epidemiology & Community Health. https://doi.org/10.1136/jech-2023-220882

Journal article

Immunotherapy for advanced urothelial carcinoma (UC): rational and current evidence
Mario Uccello, Sola Adeleke, Michele Moschetta, Aruni Ghose and Stergios Boussios 2023. Immunotherapy for advanced urothelial carcinoma (UC): rational and current evidence. Annals of Palliative Medicine. https://doi.org/10.21037/apm-22-1350

Journal article

Clinical challenges in the management of malignant ovarian germ cell tumours
Iqra Saani, Nitish Raj, Raja Sood, Shahbaz Ansari, Haider Abbas Mandviwala, Elisabet Sanchez and Stergios Boussios 2023. Clinical challenges in the management of malignant ovarian germ cell tumours. International Journal of Environmental Research and Public Health. 20 (12), p. 6089.

Journal article

Impact of COVID-19 on cancer services and patients' outcomes: a retrospective single-center study
Baijaeek Sain, Arnab Gupta, Aruni Ghose, Sudip Halder, Samir Bhattacharya, Radha Raman Mondal, Subhamoy Paul, Chandrakanth Are and Stergios Boussios 2023. Impact of COVID-19 on cancer services and patients' outcomes: a retrospective single-center study. Annals of Translational Medicine. 11 (9). https://doi.org/10.21037/atm-22-5876

Journal article

Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial
Farooq, Saeed, Sheikh, Saima, Dikomitis, Lisa, Haq Mian Mukhtar, Ul, Khan, Abdul Jalil, Sanauddin, Noor, Ali, Malik Wajid, Ali, Johar, Khan, Muhammad Firaz, Chaudhry, Imran, Husain, Nusrat, Gul, Muhammad, Irfan, Muhammad, Andrews, Gabrielle, Kaistha, Prachi, Shah, Syed Muhammad Uzair, Azeemi, Ishfaq, Hamid, Shumaila, Minhaz, Aaliya, Mallen, Christian and Lewis, Martyn 2023. Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial. BMJ Open. 13 (7), p. e072471. https://doi.org/10.1136/bmjopen-2023-072471

Journal article

Dysglycemia and arrhythmias
Sun, Dong-Kun, Zhang, Nan, Liu, Ying, Qiu, Jiu-Chun, Tse, Gary, Li, Guang-Ping, Roever, Leonardo and Liu, Tong 2023. Dysglycemia and arrhythmias. World Journal of Diabetes. 14 (8), pp. 1163-1177. https://doi.org/10.4239/wjd.v14.i8.1163

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Safeguarding community-centred global health research during crises
Agampodi, T., Nuwangi, H., Gunasekara, Sonali, Mallawaarachchi, Asitha, Price, Helen P, Dikomitis, Lisa and Agampodi, S. 2023. Safeguarding community-centred global health research during crises. BMJ Global Health. 8 (8), p. e013304. https://doi.org/10.1136/bmjgh-2023-013304

Journal article

Association of Life’s Essential 8 with incident atherosclerotic cardiovascular disease in cancer patients: the Kailuan prospective cohort study
Zhang, Nan, Wei, Zhihao, Zhang, Yunpeng, Zhang, Qingling, Chen, Ziliang, Tse, Gary, Li, Guangping, Liu, T. and Wu, Shouling 2023. Association of Life’s Essential 8 with incident atherosclerotic cardiovascular disease in cancer patients: the Kailuan prospective cohort study. European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwad256

Journal article

Association between serum uric acid and prostate cancer mortality in androgen deprivation therapy: A population‐based cohort study
Lee, Y., Chan, J., Leung, Chi Ho, Hui, J., Dee, E., Ng, Kenrick, Liu, Kang, Liu, T., Tse, Gary and Ng, Chi Fai 2023. Association between serum uric acid and prostate cancer mortality in androgen deprivation therapy: A population‐based cohort study. Cancer Medicine. https://doi.org/10.1002/cam4.6344

Journal article

Advances in adoptive T-cell therapy for metastatic melanoma
Das, Aparimita, Ghose, Aruni, Naicker, Kevin, Sanchez, Elisabet, Chargari, Cyrus, Rassy, Elie and Boussios, S. 2023. Advances in adoptive T-cell therapy for metastatic melanoma. Current Research in Translational Medicine. 71 (3), p. 103404. https://doi.org/10.1016/j.retram.2023.103404

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Association between psychological distress and cardiovascular health amongst cancer survivors in the United States: findings from nationally representative data
Jeffrey Shi Kai Chan, Danish Iltaf Satti, Edward Christopher Dee, Garima Sharma, Salim S Virani, Tong Liu and Gary Tse 2023. Association between psychological distress and cardiovascular health amongst cancer survivors in the United States: findings from nationally representative data . European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwad162

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Temporal trends in cardiovascular burden among patients with prostate cancer receiving androgen deprivation therapy: a population-based cohort study
Jeffrey Shi Kai Chan, Danish Iltaf Satti, Yan Hiu Athena Lee, Jeremy Man Ho Hui, Edward Christopher Dee, Kenrick Ng, Kang Liu, Gary Tse and Chi Fai Ng 2023. Temporal trends in cardiovascular burden among patients with prostate cancer receiving androgen deprivation therapy: a population-based cohort study. British Journal of Cancer. 128, pp. 2253-2260. https://doi.org/10.1038/s41416-023-02271-5

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Virtual medical research mentoring
Chan, J., Lau, Dawnie Ho Hei, King, Emma, Roever, Leonardo, Liu, Tong, Shum, Yuki Ka Ling, Ng, Kenrick, Dee, Edward Christopher, Ciobanu, Ana, Bazoukis, George, Mahmoudi, Elham, Satti, Danish Iltaf, Jeevaratnam, Kamalan, Baranchuk, Adrian and Tse, Gary 2023. Virtual medical research mentoring. The Clinical Teacher. 20 (4). https://doi.org/10.1111/tct.13598

Journal article

Predictors of ventricular arrhythmias in patients with mitral valve prolapse: A meta-analysis
Bazoukis, George, Saplaouras, Athanasios, Vlachos, Konstantinos, Mililis, Panagiotis, Letsas, Konstantinos P, Efremidis, Michael, Liu, Tong and Tse, Gary 2023. Predictors of ventricular arrhythmias in patients with mitral valve prolapse: A meta-analysis. Cardiology in Review. https://doi.org/10.1097/CRD.0000000000000577

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Barriers and shortcomings in access to cardiovascular management and prevention for familial hypercholesterolemia during the COVID-19 pandemic
Helen Huang, Keith S. K. Leung, Tulika Garg, Adele Mazzoleni, Goshen D. Miteu, Farida Zakariya, Wireko A. Awuah, Elaine T. S. Yin, Faaraea Haroon, Zarish Hussain, Narjiss Aji, Vikash Jaiswal and Gary Tse 2023. Barriers and shortcomings in access to cardiovascular management and prevention for familial hypercholesterolemia during the COVID-19 pandemic. Clinical Cardiology. https://doi.org/10.1002/clc.24059

Journal article

Prostate cancer - what about oligometastatic disease and stereotactic ablative radiotherapy? - a narrative review
Boussios, S., Saxby, H. and Mikropoulos, C. 2023. Prostate cancer - what about oligometastatic disease and stereotactic ablative radiotherapy? - a narrative review. Annals of Palliative Medicine. 12 (3). https://doi.org/10.21037/apm-22-828

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Risk stratification of sudden cardiac death in asymptomatic female Brugada syndrome patients: A literature review
Keith Sai Kit Leung, Danny Radford, Helen Huang, Ishan Lakhani, Christien Ka Hou Li, Sandeep Singh Hothi, Abraham Ka Chung Wai, Tong Liu, Gary Tse and Sharen Lee 2023. Risk stratification of sudden cardiac death in asymptomatic female Brugada syndrome patients: A literature review. Annals of Noninvasive Electrocardiology. 28 (2), p. e13030. https://doi.org/10.1111/anec.13030

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Emerging sodium-glucose cotransporter-2 inhibitor therapies for managing heart failure in patients with chronic kidney disease
Jeffrey Shi Kai Chan, Francesco Perone, Yasmin Bayatpoor, Gary Tse and Amer Harky 2023. Emerging sodium-glucose cotransporter-2 inhibitor therapies for managing heart failure in patients with chronic kidney disease. Expert Opinion on Pharmacotherapy. 24 (8). https://doi.org/10.1080/14656566.2023.2204188

Journal article

Metformin use and hospital attendance-related resources utilization among diabetic patients with prostate cancer on androgen deprivation therapy: A population-based cohort study
Yan Hiu Athena Lee, Jeremy Man Ho Hui, Cheuk To Chung, Kang Liu, Edward Christopher Dee, Kenrick Ng, Gary Tse, Jeffrey Shi Kai Chan and Chi Fai Ng 2023. Metformin use and hospital attendance-related resources utilization among diabetic patients with prostate cancer on androgen deprivation therapy: A population-based cohort study. Cancer Medicine. 12 (8), pp. 9128-9132. https://doi.org/10.1002/cam4.5651

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HPV and cervical cancer: A review of epidemiology and screening uptake in the UK
Sunyoung Choi, Ayden Ismail, George Pappas-Gogos and Stergios Boussios 2023. HPV and cervical cancer: A review of epidemiology and screening uptake in the UK. Pathogens (Basel, Switzerland). 12 (2). https://doi.org/10.3390/pathogens12020298

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Reverse atrial remodeling in heart failure with recovered ejection fraction
Yuxi Sun, Xuefu Chen, Yanli Zhang, Yao Yu, Xinxin Zhang, Jinping Si, Zijie Ding, Yunlong Xia, Gary Tse and Ying Liu 2023. Reverse atrial remodeling in heart failure with recovered ejection fraction. Journal of the American Heart Association. 12, p. e026891. https://doi.org/10.1161/JAHA.122.026891

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The association between neutrophil-lymphocyte ratio and variability with new-onset dementia: A population-based cohort study
Chou, Oscar Hou In, Zhou, Jiandong, Li, Lifang, Chan, Jeffrey Shi Kai, Satti, Danish Iltaf, Chou, Vanessa Hou Cheng, Wong, Wing Tak, Lee, Sharen, Cheung, Bernard Man Yung, Tse, Gary, Chang, Carlin and Liu, Tong 2023. The association between neutrophil-lymphocyte ratio and variability with new-onset dementia: A population-based cohort study. Journal of Alzheimer's Disease. 94 (2), pp. 547-557. https://doi.org/10.3233/jad-220111

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Long-term prognostic impact of cardiovascular comorbidities in patients with prostate cancer receiving androgen deprivation therapy: A population-based competing risk analysis.
Chan, J., Lee, Yan Hiu Athena, Hui, Jeremy Man Ho, Liu, Kang, Dee, Edward Christopher, Ng, Kenrick, Liu, T., Tse, Gary and Ng, Chi Fai 2023. Long-term prognostic impact of cardiovascular comorbidities in patients with prostate cancer receiving androgen deprivation therapy: A population-based competing risk analysis. International Journal of Cancer. https://doi.org/10.1002/ijc.34557

Journal article

Combination of SVI/S′ and diagnostic scores for heart failure with preserved ejection fraction
Mu, Guanyu, Wang, Weiding, Liu, Changle, Xie, Juan, Zhang, Hao, Zhang, Xiaowei, Che, Jingjin, Tse, Gary, Liu, T., Li, Guangping, Fu, Huaying and Chen, K. 2023. Combination of SVI/S′ and diagnostic scores for heart failure with preserved ejection fraction. Clinical and Experimental Pharmacology and Physiology. https://doi.org/10.1111/1440-1681.13782

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'We do not rush to the hospital for ordinary wounds (suḷu tuvāla)': A qualitative study on the early clinical manifestations of cutaneous leishmaniasis and associated health behaviours in rural Sri Lanka.
Gunasekara, Sonali Dinushika, Wickramasinghe, Nuwan Darshana, Agampodi, S., Fernando, Manoj Sanjeewa, Weerakoon, Kosala Gayan, Liyanage, Chandani, Dikomitis, Lisa and Agampodi, Thilini Chanchala 2023. 'We do not rush to the hospital for ordinary wounds (suḷu tuvāla)': A qualitative study on the early clinical manifestations of cutaneous leishmaniasis and associated health behaviours in rural Sri Lanka. PLoS Neglected Tropical Diseases. 17 (5), p. e0010939. https://doi.org/10.1371/journal.pntd.0010939

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Lower risks of new-onset acute pancreatitis and pancreatic cancer in sodium glucose cotransporter 2 (SGLT2) inhibitors compared to dipeptidyl peptidase-4 (DPP4) inhibitors: A propensity score-matched study with competing risk analysis
Tse, G. 2023. Lower risks of new-onset acute pancreatitis and pancreatic cancer in sodium glucose cotransporter 2 (SGLT2) inhibitors compared to dipeptidyl peptidase-4 (DPP4) inhibitors: A propensity score-matched study with competing risk analysis. Diabetes Epidemiology and Management. 9, p. 100115. https://doi.org/10.1016/j.deman.2022.100115

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Sodium‐glucose cotransporter 2 inhibitors versus dipeptidyl peptidase 4 inhibitors on new‐onset overall cancer in Type 2 diabetes mellitus: A population‐based study
Chung, Cheuk To, Lakhani, Ishan, Chou, Oscar Hou In, Lee, Teddy Tai Loy, Dee, Christopher, Ng, Kendrick, Wong, Wing Tak, Liu, T., Lee, Sharen, Zhang, Qingpeng, Cheung, Bernard Man Yung, Tse, Gary and Zhou, Jiandong 2023. Sodium‐glucose cotransporter 2 inhibitors versus dipeptidyl peptidase 4 inhibitors on new‐onset overall cancer in Type 2 diabetes mellitus: A population‐based study. Cancer Medicine. https://doi.org/10.1002/cam4.5927

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The role of electrophysiological study in the risk stratification of Brugada Syndrome
Bazoukis, George, Chung, Cheuk To, Vassiliou, Vassilios S, Sfairopoulos, Dimitrios, Lee, Sharen, Papadatos, Stamatis S, Korantzopoulos, Panagiotis, Saplaouras, Athanasios, Letsas, Konstantinos P, Liu, Tong and Tse, Gary 2023. The role of electrophysiological study in the risk stratification of Brugada Syndrome. Cardiology in Review. https://doi.org/10.1097/CRD.0000000000000561

Journal article

Metformin use and mortality in Asian, diabetic patients with prostate cancer on androgen deprivation therapy: A population-based study
Yan Hiu Athena Lee, Jeremy Man Ho Hui, Jeffrey Shi Kai Chan, Kang Liu, Edward C. Dee, Kenrick Ng, Pias Tang and Tse, G. 2023. Metformin use and mortality in Asian, diabetic patients with prostate cancer on androgen deprivation therapy: A population-based study. The Prostate. 83 (1), pp. 119-127. https://doi.org/10.1002/pros.24443

Journal article

Predictive value of neutrophil-to-lymphocyte ratio for atrial fibrillation and stroke in type 2 diabetes mellitus: The Hong Kong Diabetes Study
Carlin Chang, Jiandong Zhou, Oscar Hou In Chou, Justin Chan, Keith Sai Kit Leung, Teddy Tai Loy Lee, Wing Tak Wong, Abraham Ka Chung Wai, Tong Liu, Qingpeng Zhang, Sharen Lee and Tse, G. 2023. Predictive value of neutrophil-to-lymphocyte ratio for atrial fibrillation and stroke in type 2 diabetes mellitus: The Hong Kong Diabetes Study. Endocrinology, Diabetes & Metabolism. https://doi.org/10.1002/edm2.397

Journal article

Socioeconomic deprivation and prognostic outcomes in acute coronary syndrome: A meta-analysis using multidimensional socioeconomic status indices.
Anand, Vickram Vijay, Zhe, Ethan Lee Cheng, Chin, Yip Han, Goh, Rachel Sze Jen, Lin, Chaoxing, Kueh, Martin Tze Wah, Chong, Bryan, Kong, Gwyneth, Tay, Phoebe Wen Lin, Dalakoti, Mayank, Muthiah, Mark, Dimitriadis, Georgios K, Wang, Jiong-Wei, Mehta, Anurag, Foo, Roger, Tse, Gary, Figtree, Gemma A, Loh, Poay Huan, Chan, Mark Y, Mamas, Mamas A and Chew, Nicholas W S 2023. Socioeconomic deprivation and prognostic outcomes in acute coronary syndrome: A meta-analysis using multidimensional socioeconomic status indices. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2023.04.042

Journal article

Long-term cardiovascular risks of Gonadotropin-releasing hormone agonists and antagonists: A population-based cohort study
Chan, J S K, Lee, Y H A, Hui, J M H, Liu, K, Dee, E C, Ng, K, Tang, P, Tse, G and Ng, C F 2023. Long-term cardiovascular risks of Gonadotropin-releasing hormone agonists and antagonists: A population-based cohort study. Clinical Oncology (Royal College of Radiologists (Great Britain)). 35 (6), pp. e376-e383. https://doi.org/10.1016/j.clon.2023.03.014

Journal article

Association between sick sinus syndrome and atrial fibrillation: A systematic review and meta-analysis.
Liu, Ying, Zheng, Yi, Tse, Gary, Bazoukis, George, Letsas, Konstantinos, Goudis, Christos, Korantzopoulos, Panagiotis, Li, Guangping and Liu, Tong 2023. Association between sick sinus syndrome and atrial fibrillation: A systematic review and meta-analysis. International Journal of Cardiology. 381, pp. 20-36. https://doi.org/10.1016/j.ijcard.2023.03.066

Journal article

Do loneliness and social exclusion breed paranoia? An experience sampling investigation across the psychosis continuum.
Bell, Victoria, Velthorst, Eva, Almansa, Jorge, Myin-Germeys, Inez, Shergill, Sukhi and Fett, Anne-Kathrin 2023. Do loneliness and social exclusion breed paranoia? An experience sampling investigation across the psychosis continuum. Schizophrenia Research: Cognition. 33, p. 100282. https://doi.org/10.1016/j.scog.2023.100282

Journal article

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