Telomere length analysis and preterm infant health: the importance of assay design in the search for novel biomarkers

Journal article

Turner, K., Vasu, V., Greenall, J. and Griffin, D. 2014. Telomere length analysis and preterm infant health: the importance of assay design in the search for novel biomarkers. Biomarkers in Medicine. 8 (4), pp. 485-498. https://doi.org/10.2217/bmm.14.13
AuthorsTurner, K., Vasu, V., Greenall, J. and Griffin, D.
Abstract

Preterm infants develop an ‘aged’ phenotype in comparison with term-born infants, one component of which is adverse metabolic health and, therefore, long-term health follow-up is warranted to identify morbidity. In light of this, the identification and use of biomarkers to aid with prognosis would be a welcome Development. Telomeres are repeat sequences at the ends of each chromosome arm known to shorten as a consequence of cellular aging, and in relation to several disease conditions. The
hypothesis that expreterm infants manifest alterations in telomere attrition rate is, therefore, one of interest. Analysis of telomere length maybe a plausible technique to predict prognosis in relation to preterm birth, and early life environmental and nutritional exposures. In this article, we review the literature on telomere length analysis in the preterm infant population and examine the tools available to measure telomere length.

Year2014
JournalBiomarkers in Medicine
Journal citation8 (4), pp. 485-498
PublisherFuture Medicine
ISSN1752-0363
Digital Object Identifier (DOI)https://doi.org/10.2217/bmm.14.13
Official URLhttp://dx,doi.org/10.2217/bmm.14.13
Publication dates
PrintApr 2014
Publication process dates
Deposited23 Jun 2017
Output statusPublished
Permalink -

https://repository.canterbury.ac.uk/item/88365/telomere-length-analysis-and-preterm-infant-health-the-importance-of-assay-design-in-the-search-for-novel-biomarkers

  • 50
    total views
  • 0
    total downloads
  • 1
    views this month
  • 0
    downloads this month

Export as

Related outputs

Morphokinetic profiling suggests that rapid first cleavage division accurately predicts the chances of blastulation in pig In vitro produced embryos
Hillyear, Lucy M., Zak, L., Beckitt, T., Griffin, D., Harvey, Simon C. and Harvey, K. 2024. Morphokinetic profiling suggests that rapid first cleavage division accurately predicts the chances of blastulation in pig In vitro produced embryos. Animals. 14 (5), p. 783. https://doi.org/10.3390/ani14050783
The role of chromosome segregation and nuclear organisation in human subfertility
Fowler, K., Mandawala, A. and Griffin, D. 2019. The role of chromosome segregation and nuclear organisation in human subfertility. Biochemical Society Transactions. 47 (1), pp. 425-432. https://doi.org/10.1042/BST20180231
The production of pig preimplantation embryos in vitro: current progress and future prospects
Fowler, K., Mandawala, A., Griffin, D., Walling, G. and Harvey, S. 2018. The production of pig preimplantation embryos in vitro: current progress and future prospects. Reproductive Biology. 18 (3), pp. 203-211. https://doi.org/10.1016/j.repbio.2018.07.001
Preterm infants have significantly longer telomeres than their term born counterparts
Vasu, V., Turner, K., George, S., Greenall, J., Slijepcevic, P. and Griffin, D. 2017. Preterm infants have significantly longer telomeres than their term born counterparts. PLoS ONE. 12 (6). https://doi.org/10.1371/journal.pone.0180082
Use of suboptimal sperm increases the risk of aneuploidy of the sex chromosomes in preimplantation blastocyst embryos
Coates, A., Hesla, J., Hurliman, A., Coate, B., Holmes, E., Matthews, R., Mounts, E., Turner, K., Thornhill, A. and Griffin, D. 2015. Use of suboptimal sperm increases the risk of aneuploidy of the sex chromosomes in preimplantation blastocyst embryos. Fertility and Sterility. 104 (4), pp. 866-872. https://doi.org/10.1016/j.fertnstert.2015.06.033
The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans
Hall, R., Turner, K., Chaloupka, J., Cottier, F., De Sordi, L., Sanglard, D., Levin, L., Buck, J. and Mühlschlegel, F. 2011. The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans. Eukaryotic Cell. 10 (8), pp. 1034-1042. https://doi.org/10.1128/EC.05060-11
Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set
Damas, J., O'Connor, R., Farré, M., Lenis, V., Martell, H., Mandawala, A., Fowler, K., Joseph, S., Swain, M., Griffin, D. and Larkin, D. 2016. Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set. Genome Research.
Multicolour detection of every chromosome as a means of detecting mosaicism and nuclear organisation in human embryonic nuclei
Turner, K., Fowler, K., Fonseka, G., Griffin, D. and Ioannou, D. 2016. Multicolour detection of every chromosome as a means of detecting mosaicism and nuclear organisation in human embryonic nuclei. Panminerva Medica.
20th International Chromosome Conference (ICCXX)
Griffin, D., Fowler, K., Ellis, P. and Jackson, D. 2015. 20th International Chromosome Conference (ICCXX). Chromosome Research. https://doi.org/10.1007/s10577-014-9447-3
Reconstruction of gross avian genome structure, organization and evolution suggests that the chicken lineage most closely resembles the dinosaur avian ancestor
Romanov, M., Farré, M., Lithgow, P., Fowler, K., Skinner, B., O'Connor, R., Fonseka, G., Backström, N., Matsuda, Y., Nishida, C., Houde, P., Jarvis, E., Hanson, E., Burt, D., Larkin, D. and Griffin, D. 2014. Reconstruction of gross avian genome structure, organization and evolution suggests that the chicken lineage most closely resembles the dinosaur avian ancestor. BMC Genomics. 15 (1060). https://doi.org/10.1186/1471-2164-15-1060
Novel approach for deriving genome wide SNP analysis data from archived blood spots
Fowler, K., Reitter, C., Walling, G. and Griffin, D. 2012. Novel approach for deriving genome wide SNP analysis data from archived blood spots. BMC Research Notes. 5 (1), p. 503. https://doi.org/10.1186/1756-0500-5-503
Analyses of pig genomes provide insight into porcine demography and evolution
Groenen, M., Archibald, A., Uenishi, H., Tuggle, C., Takeuchi, Y., Rothschild, M., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H., Li, S., Larkin, D., Kim, H., Frantz, L., Caccamo, M., Ahn, H., Aken, B., Anselmo, A., Anthon, C., Auvil, L., Badaoui, B., Beattie, C., Bendixen, C., Berman, D., Blecha, F., Blomberg, J., Bolund, L., Bosse, M., Botti, S., Bujie, Z., Bystrom, M., Capitanu, B., Carvalho-Silva, D., Chardon, P., Chen, C., Cheng, R., Choi, S., Chow, W., Clark, R., Clee, C., Crooijmans, R., Dawson, H., Dehais, P., De Sapio, F., Dibbits, B., Drou, N., Du, Z., Eversole, K., Fadista, J., Fairley, S., Faraut, T., Faulkner, G., Fowler, K., Fredholm, M., Fritz, E., Gilbert, J., Giuffra, E., Gorodkin, J., Griffin, D., Harrow, J., Hayward, A., Howe, K., Hu, Z., Humphray, S., Hunt, T., Hornshøj, H., Jeon, J., Jern, P., Jones, M., Jurka, J., Kanamori, H., Kapetanovic, R., Kim, J., Kim, J., Kim, K., Kim, T., Larson, G., Lee, K., Lee, K., Leggett, R., Lewin, H., Li, Y., Liu, W., Loveland, J., Lu, Y., Lunney, J., Ma, J., Madsen, O., Mann, K., Matthews, L., McLaren, S., Morozumi, T., Murtaugh, M., Narayan, J., Truong Nguyen, D., Ni, P., Oh, S., Onteru, S., Panitz, F., Park, E., Park, H., Pascal, G., Paudel, Y., Perez-Enciso, M., Ramirez-Gonzalez, R., Reecy, J., Rodriguez-Zas, S., Rohrer, G., Rund, L., Sang, Y., Schachtschneider, K., Schraiber, J., Schwartz, J., Scobie, L., Scott, C., Searle, S., Servin, B., Southey, B., Sperber, G., Stadler, P., Sweedler, J., Tafer, H., Thomsen, B., Wali, R., Wang, J., Wang, J., White, S., Xu, X., Yerle, M., Zhang, G., Zhang, J., Zhang, J., Zhao, S., Rogers, J., Churcher, C. and Schook, L. 2012. Analyses of pig genomes provide insight into porcine demography and evolution. Nature. 491 (7424), pp. 393-398. https://doi.org/10.1038/nature11622
Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis
Skinner, B., Robertson, L., Tempest, H., Langley, E., Ioannou, D., Fowler, K., Crooijmans, R., Hall, A., Griffin, D. and Völker, M. 2009. Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis. BMC Genomics. 10 (1), p. 357. https://doi.org/10.1186/1471-2164-10-357
Genome wide analysis reveals single nucleotide polymorphisms associated with fatness and putative novel copy number variants in three pig breeds
Fowler, K., Pong-Wong, R., Bauer, J., Clemente, E., Reitter, C., Affara, N., Waite, S., Walling, G. and Griffin, D. 2013. Genome wide analysis reveals single nucleotide polymorphisms associated with fatness and putative novel copy number variants in three pig breeds. BMC Genomics. 14 (1), p. 784. https://doi.org/10.1186/1471-2164-14-784
Identification of putative sex chromosomes in the blue tilapia, Oreochromis aureus, through synaptonemal complex and FISH analysis
Campos-Ramos, R., Harvey, S., Masabanda, J., Carrasco, L., Griffin, D., McAndrew, B., Bromage, N. and Penman, D. 2001. Identification of putative sex chromosomes in the blue tilapia, Oreochromis aureus, through synaptonemal complex and FISH analysis. Genetica. 111 (1/3), pp. 143-153. https://doi.org/10.1023/A:1013707818534
Molecular-cytogenetic analysis reveals sequence differences between the sex chromosomes of Oreochromis niloticus: evidence for an early stage of sex-chromosome differentiation
Harvey, S., Masabanda, J., Carrasco, L., Bromage, N., Penman, D. and Griffin, D. 2002. Molecular-cytogenetic analysis reveals sequence differences between the sex chromosomes of Oreochromis niloticus: evidence for an early stage of sex-chromosome differentiation. Cytogenetic and Genome Research. 97 (1-2), pp. 76-80. https://doi.org/10.1159/000064036
Karyotype evolution in tilapia: mitotic and meiotic chromosome analysis of Oreochromis Karongae and O. Niloticus × O. Karongae hybrids
Harvey, S., Campos-Ramos, R., Kennedy, D., Ezaz, M., Bromage, N., Griffin, D. and Penman, D. 2002. Karyotype evolution in tilapia: mitotic and meiotic chromosome analysis of Oreochromis Karongae and O. Niloticus × O. Karongae hybrids. Genetica. 115 (2), pp. 169-177. https://doi.org/10.1023/A:1020190918431
Early origins of the X and Y chromosomes: lessons from tilapia
Griffin, D., Harvey, S., Campos-Ramos, R., Ayling, L., Bromage, N., Masabanda, J. and Penman, D. 2002. Early origins of the X and Y chromosomes: lessons from tilapia. Cytogenetic and Genome Research. 99 (1-4), pp. 157-163. https://doi.org/10.1159/000071588
Analysis of repetitive DNA sequences in the sex chromosomes of Oreochromis niloticus
Harvey, S., Boonphakdee, C., Campos-Ramos, R., Ezaz, M., Griffin, D., Bromage, N. and Penman, D. 2003. Analysis of repetitive DNA sequences in the sex chromosomes of Oreochromis niloticus. Cytogenetic and Genome Research. 101 (3-4), pp. 314-319. https://doi.org/10.1159/000074355
Practicable approaches to facilitate rapid and accurate molecular cytogenetic mapping in birds and mammals
Morris, W., Stephenson, J., Robertson, L., Turner, K., Brown, H., Ioannou, D., Tempest, H., Skinner, B. and Griffin, D. 2007. Practicable approaches to facilitate rapid and accurate molecular cytogenetic mapping in birds and mammals. Cytogenetic and Genome Research. 117 (1-4), pp. 36-42. https://doi.org/10.1159/issn.1424-8581