Professor Sukhwinder Singh Shergill


NameProfessor Sukhwinder Singh Shergill
Job titleProfessor of Psychiatry
Research instituteKent and Medway Medical School (KMMS)
ORCIDhttps://orcid.org/0000-0003-4928-9100 (unauthenticated)

Research outputs

Monitoring daily sleep, mood, and affect using digital technologies and wearables: A systematic review

D'Oliveira, T., Shergill, S., Hickman, R. and Davies, A. 2024. Monitoring daily sleep, mood, and affect using digital technologies and wearables: A systematic review. Sensors. 24 (14), p. 4701. https://doi.org/10.3390/s24144701

Deterioration in cognitive control related mPFC function underlying development of treatment resistance in early psychosis.

Crisp, C., Sahni, Angad, Pang, Sze W, Vanes, Lucy D, Szentgyorgyi, Timea, Averbeck, B., Moran, Rosalyn J and Shergill, Sukhwinder S 2024. Deterioration in cognitive control related mPFC function underlying development of treatment resistance in early psychosis. Scientific Reports. 14 (1), p. 12985. https://doi.org/10.1038/s41598-024-63474-1

Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context.

Taher, R., Bhanushali, Palak, Allan, S., Alvarez-Jimenez, Mario, Bolton, Heather, Dennison, Laura, Wallace, Brian E., Hadjistavropoulos, Heather D, Hall, Charlotte L, Hardy, Amy, Henry, A., Lane, Sam, Maguire, Tess, Moreton, Adam, Moukhtarian, Talar R., Vallejos, Elvira Perez, Shergill, Sukhi, Stahl, Daniel, Thew, Graham R., Timulak, Ladislav, van den Berg, David, Viganò, Noemi, Stock, Ben Wensley, Young, Katherine S. and Yiend, Jenny 2024. Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context. BJPsych Open. 10 (4), p. e126. https://doi.org/10.1192/bjo.2024.713

Understanding the mechanisms underlying cognitive control in psychosis

Maitra, R., Lemmers-Jansen, I L J, Vooren, M, Vanes, Lucy, Szentgyorgyi, Timea, Crisp, Charlotte, Mouchlianitis, Elias and Shergill, S S 2024. Understanding the mechanisms underlying cognitive control in psychosis. Psychological Medicine. https://doi.org/10.1017/S0033291724001119

Investigating cortical excitability and inhibition in patients with schizophrenia: A TMS-EEG study.

Santoro, V, Hou, M D, Premoli, I, Belardinelli, P, Biondi, A, Carobin, A, Puledda, F, Michalopoulou, P G, Richardson, M P, Rocchi, L and Shergill, S S 2024. Investigating cortical excitability and inhibition in patients with schizophrenia: A TMS-EEG study. Brain research bulletin. 212, p. 110972. https://doi.org/10.1016/j.brainresbull.2024.110972

Sikh silences across generations

Dikomitis, L., Shergill, S. and Dikomitis, E. 2024. Sikh silences across generations. Anthropology News.

Connectome dysfunction in patients at clinical high risk for psychosis and modulation by oxytocin

Davies, C., Martins, D., Dipasquale, O., McCutcheon, Robert A, De Micheli, Andrea, Ramella-Cravaro, Valentina, Provenzani, Umberto, Rutigliano, Grazia, Cappucciati, Marco, Oliver, D., Williams, S., Zelaya, Fernando, Allen, Paul, Murguia, Silvia, Taylor, David, Shergill, Sukhi, Morrison, Paul, McGuire, P., Paloyelis, Y. and Fusar-Poli, P. 2024. Connectome dysfunction in patients at clinical high risk for psychosis and modulation by oxytocin. Molecular Psychiatry. https://doi.org/10.1038/s41380-024-02406-x

A retrospective study of intramuscular clozapine prescription for treatment initiation and maintenance in treatment-resistant psychosis

Whiskey, E., Shergill, S. and Dzahini, O. 2020. A retrospective study of intramuscular clozapine prescription for treatment initiation and maintenance in treatment-resistant psychosis. British Journal of Psychiatry.

The safety of digital mental health interventions: Systematic review and recommendations

Taher, R., Hsu, C., Hampshire, C., Fialho, C., Heaysman, C., Stahl, D., Shergill, S. and Yiend, J. 2023. The safety of digital mental health interventions: Systematic review and recommendations. JMIR Mental Health. 10, p. e47433. https://doi.org/10.2196/47433

Neuroimaging glutamatergic mechanisms differentiating antipsychotic treatment-response

Mouchlianitis, Elias D, Vanes, Lucy D, Tracy, Derek K, Fett, Anne-Katherin, Joyce, Daniel and Shergill, Sukhi S 2023. Neuroimaging glutamatergic mechanisms differentiating antipsychotic treatment-response. Scientific Reports. 13 (1), p. 8938. https://doi.org/10.1038/s41598-022-26702-0

Do loneliness and social exclusion breed paranoia? An experience sampling investigation across the psychosis continuum.

Bell, Victoria, Velthorst, Eva, Almansa, Jorge, Myin-Germeys, Inez, Shergill, Sukhi and Fett, Anne-Kathrin 2023. Do loneliness and social exclusion breed paranoia? An experience sampling investigation across the psychosis continuum. Schizophrenia Research: Cognition. 33, p. 100282. https://doi.org/10.1016/j.scog.2023.100282

Automatic detection of cognitive impairment with virtual reality

Mannan, Farzana A, Porffy, Lilla A, Joyce, Dan W, Shergill, Sukhwinder S and Celiktutan, O. 2023. Automatic detection of cognitive impairment with virtual reality. Sensors. 23 (2), p. 1026. https://doi.org/10.3390/s23021026

VStore: Feasibility and acceptability of a novel virtual reality functional cognition task

Lilla A. Porffy, Mitul A. Mehta, Elias Mouchlianitis and Sukhi S. Shergill 2022. VStore: Feasibility and acceptability of a novel virtual reality functional cognition task. Frontiers in Virtual Reality.

Stimulating learning: A functional MRI and behavioral investigation of the effects of transcranial direct current stimulation on stochastic learning in schizophrenia

Natasza D. Orlov, Syed Ali Muqtadir, Hooman Oroojeni, Bruno Averbeck, John Rothwell and Sukhi S. Shergill 2022. Stimulating learning: A functional MRI and behavioral investigation of the effects of transcranial direct current stimulation on stochastic learning in schizophrenia. Psychiatry Research. 317, p. 114908. https://doi.org/10.1016/j.psychres.2022.114908

Alpha3/alpha2 power ratios relate to performance on a virtual reality shopping task in ageing adults

Patchitt, Joel, Porffy, Lilla A., Whomersley, Gabriella, Szentgyorgyi, Timea, Brett, Jack, Mouchlianitis, Elias, Mehta, Mitul A., Nottage, Judith F. and Shergill, Sukhi S. 2022. Alpha3/alpha2 power ratios relate to performance on a virtual reality shopping task in ageing adults. Frontiers in Aging Neuroscience. 14, p. 876832. https://doi.org/10.3389/fnagi.2022.876832

The influence of trial-by-trial feedback on trust in health, first-episode and chronic psychosis

Lemmers-Jansen, I., Wichmann, Rune J., Perizonius, Sophie and Shergill, Sukhi S. 2022. The influence of trial-by-trial feedback on trust in health, first-episode and chronic psychosis. Games. 13 (5), p. e59. https://doi.org/10.3390/g13050059

Relaxation of the criteria for entry to the UK Clozapine Central Non-Rechallenge Database: a modelling study

Ebenezer Oloyede, Eromona Whiskey, Cecilia Casetta, Olubanke Dzahini, Danielle Dunnett, Shreyans Gandhi, Prof Fiona Gaughran, Prof Sukhi Shergill, Prof Philip McGuire, Prof James H MacCabe and Prof David Taylor 2022. Relaxation of the criteria for entry to the UK Clozapine Central Non-Rechallenge Database: a modelling study. The Lancet: Psychiatry. 9 (8), pp. 636-644. https://doi.org/10.1016/S2215-0366(22)00188-2

Vortioxetine as adjunctive therapy in the treatment of schizophrenia

Redaelli, Sofia, Porffy, Lilla, Oloyede, Ebenezer, Dzahini, O., Lewis, Gabriella, Lobo, Maria, Whiskey, E. and Shergill, Sukhi S. 2022. Vortioxetine as adjunctive therapy in the treatment of schizophrenia. Therapeutic Advances in Psychopharmacology. 12, p. 204512532211100. https://doi.org/10.1177/20451253221110014

Cognitive bias modification for paranoia (CBM-pa): a randomised controlled feasibility study in patients with distressing paranoid beliefs.

Yiend, Jenny, Lam, C., Schmidt, Nora, Crane, Bryony, Heslin, Margaret, Kabir, Thomas, McGuire, Philip, Meek, Christopher, Mouchlianitis, Elias, Peters, Emmanuelle, Stahl, Daniel, Trotta, Antonella and Shergill, Sukhwinder 2022. Cognitive bias modification for paranoia (CBM-pa): a randomised controlled feasibility study in patients with distressing paranoid beliefs. Psychological Medicine. https://doi.org/10.1017/S0033291722001520

Why care about integrated care? Part 3. Weighing sunlight: delivering integration in practice and measuring success

Tracy, D. K., Hanson, K., Underwood, B. R. and Shergill, S. 2022. Why care about integrated care? Part 3. Weighing sunlight: delivering integration in practice and measuring success. BJPsych Advances. 29 (1), pp. 31-40. https://doi.org/10.1192/bja.2022.26

The role of cognitive control in the positive symptoms of psychosis

Horne, Charlotte M., Sahni, Angad, Pang, Sze W., Vanes, Lucy D., Szentgyorgyi, Timea, Averbeck, Bruno, Moran, Rosalyn J. and Shergill, Sukhwinder S. 2022. The role of cognitive control in the positive symptoms of psychosis. NeuroImage. Clinical. 34, p. 103004. https://doi.org/S2213-1582(22)00069-9

Direct eye gaze enhances the ventriloquism effect

Lavan, N., Chan, Wing Yue, Zhuang, Yongping, Mareschal, Isabelle and Shergill, Sukhwinder S. 2022. Direct eye gaze enhances the ventriloquism effect. Attention, Perception & Psychophysics. https://doi.org/10.3758/s13414-022-02468-5

A novel virtual reality assessment of functional cognition: Validation study

Lilla Alexandra Porffy, Mitul A Mehta, Joel Patchit, Celia Boussebaa, Jack Brett, Teresa D’Oliveira, Elias Mouchlianitis and Sukhi Shergill. 2022. A novel virtual reality assessment of functional cognition: Validation study. Journal of Medical Internet Research. 24 (1), p. e27641. https://doi.org/10.2196/27641

A systematic review of TMS and neurophysiological biometrics in patients with schizophrenia

di Hou, Meng, Santoro, Viviana, Biondi, Andrea, Shergill, Sukhi S and Premoli, Isabella 2021. A systematic review of TMS and neurophysiological biometrics in patients with schizophrenia. Journal of psychiatry & neuroscience : JPN. 46 (6), pp. E675-E701. https://doi.org/10.1503/jpn.210006

Outcomes in treatment-resistant schizophrenia: symptoms, function and clozapine plasma concentrations

Shergill, S., Amir Krivoy, Eromona Whiskey, Henrietta Webb-Wilson, Dan Joyce, Derek K. Tracy, Fiona Gaughran, James H. MacCabe and Sukhwinder S. Shergill 2021. Outcomes in treatment-resistant schizophrenia: symptoms, function and clozapine plasma concentrations. Therapeutic Advances in Psychopharmacology. 11. https://doi.org/10.1177/20451253211037179

The importance of pro-social processing, and ameliorating dysfunction in schizophrenia. An FMRI study of oxytocin

Shergill, S., Rebekah Wigton, Derek K. Tracy, Tess M. Verneuil, Michaela Johns, Thomas White, Panayiota G. Michalopoulou, Bruno Averbeck and Sukhwinder Shergill 2022. The importance of pro-social processing, and ameliorating dysfunction in schizophrenia. An FMRI study of oxytocin. Schizophrenia Research: Cognition. 27. https://doi.org/10.1016/j.scog.2021.100221

New approaches to antipsychotic medication adherence – safety, tolerability and acceptability

Taub, Sharon, Krivoy, Amir, Whiskey, Eromona and Shergill, Sukhi S. 2021. New approaches to antipsychotic medication adherence – safety, tolerability and acceptability. Expert Opinion on Drug Safety. 21 (4), pp. 517-524. https://doi.org/10.1080/14740338.2021.1983540

Contextual perception under active inference

Berk Mirza, M., Cullen, M., Parr, T., Shergill, S. and Moran, R. 2021. Contextual perception under active inference. Scientific Reports. 11 (16223). https://doi.org/s41598-021-95510-9

Preliminary evidence for the phosphodiesterase type-4 inhibitor, roflumilast, in ameliorating cognitive flexibility deficits in patients with schizophrenia

Nicholas R Livingston, Peter CT Hawkins, James Gilleen, Rong Ye, Lorena Valdearenas, Sukhi Shergill and Mitul A Mehta 2021. Preliminary evidence for the phosphodiesterase type-4 inhibitor, roflumilast, in ameliorating cognitive flexibility deficits in patients with schizophrenia. Journal of Psychopharmacology. 35 (9). https://doi.org/10.1177/02698811211000778

The effect of training intensity on implicit learning rates in schizophrenia

Natasza D. Orlov, Jessica Sanderson, Syed Ali Muqtadir, Anastasia K. Kalpakidou, Panayiota G. Michalopoulou, Jie Lu and Sukhi S. Shergill 2021. The effect of training intensity on implicit learning rates in schizophrenia. Scientific Reports. 11 (6511). https://doi.org/10.1038/s41598-021-85686-5

An evaluation of the variation and underuse of clozapine in the United Kingdom

Eromona Whiskey, Alex Barnard, Ebenezer Oloyede, Olubanke Dzahini, David M. Taylor and Sukhwinder S. Shergill 2021. An evaluation of the variation and underuse of clozapine in the United Kingdom. Acta Psychiatrica Scandinavica. 143 (4), pp. 339-347. https://doi.org/10.1111/acps.13280

There is life after the UK Clozapine Central Non-Rechallenge Database

Ebenezer Oloyede, Cecilia Casetta, Olubanke Dzahini, Aviv Segev, Fiona Gaughran, Sukhi Shergill, Alek Mijovic, Marinka Helthuis, Eromona Whiskey, James Hunter MacCabe and David Taylor 2021. There is life after the UK Clozapine Central Non-Rechallenge Database . Schizophrenia Bulletin. 47 (4), pp. 1088-1098. https://doi.org/10.1093/schbul/sbab006

If not now, when? Enhancing cardiologists’ psychological well-being as a COVID-19 gain

Rishi K Patel, Mark D Sweeney, Christopher S R Baker, Neil Greenberg, Susan E Piper, Sukhi S. Shergill, Derek K Tracy and Carla M Plymen 2021. If not now, when? Enhancing cardiologists’ psychological well-being as a COVID-19 gain. Heart. 2021 (107), pp. 593-595. https://doi.org/10.1136/heartjnl-2020-318852

Cognitive performance in early, treatment-resistant psychosis patients: Could cognitive control play a role in persistent symptoms?

Shergill, S., Megan Thomas, Timea Szentgyorgy, Lucy D. Vanes, Elias Mouchlianitis, Erica F. Barry, Krisna Patel, Katie Wong and Dan Joyce 2021. Cognitive performance in early, treatment-resistant psychosis patients: Could cognitive control play a role in persistent symptoms? Psychiatry Research. 295, p. 113607.

The effects of roflumilast, a phosphodiesterase type-4 inhibitor, on EEG biomarkers in schizophrenia: A randomised controlled trial

James Gilleen, Judith Nottage, Farah Yakub, Sarah Kerins, Lorena Valdearenas, Tolga Uz, Gez Lahu, Max Tsai, Frank Ogrinc, Steve C Williams, Dominic Ffytche, Mitul A Mehta and Sukhi Shergill 2021. The effects of roflumilast, a phosphodiesterase type-4 inhibitor, on EEG biomarkers in schizophrenia: A randomised controlled trial. Journal of Psychopharmacology. 35 (1), pp. 15-22. https://doi.org/10.1177/0269881120946300

Real-world effectiveness of admissions to a tertiary treatment-resistant psychosis service: 2-year mirror-image study

Cecilia Casetta, Fiona Gaughran, Ebenezer Oloyede, Juliana Onwumere, Megan Pritchard, Sukhi S. Shergill, Eromona Whiskey and James Hunter MacCabe 2020. Real-world effectiveness of admissions to a tertiary treatment-resistant psychosis service: 2-year mirror-image study. BJPsych Open. 6 (5), p. E82. https://doi.org/10.1192/bjo.2020.51

Acute oxytocin effects in inferring others' beliefs and social emotions in people at clinical high risk for psychosis

André Schmidt, Cathy Davies, Yannis Paloyelis, Nicholas Meyer, Andrea De Micheli, Valentina Ramella-Cravaro, Umberto Provenzani, Yuta Aoki, Grazia Rutigliano, Marco Cappucciati, Dominic Oliver, Silvia Murguia, Fernando Zelaya, Paul Allen, Sukhi Shergill, Paul Morrison, Steve Williams, David Taylor, Stefan Borgwardt, Hidenori Yamasue, Philip McGuire and Paolo Fusar-Poli 2020. Acute oxytocin effects in inferring others' beliefs and social emotions in people at clinical high risk for psychosis. Translational Psychiatry. 10 (203). https://doi.org/10.1038/s41398-020-00885-4

Biased interpretation in paranoia and its modification

George Savulich, Annabel Edwards, Sara Assadi, Husniye Guven, Emily Leathers-Smith, Sukhi Shergill and Jenny Yiend 2020. Biased interpretation in paranoia and its modification. Journal of Behavior Therapy and Experimental Psychiatry. 69, p. 101575. https://doi.org/10.1016/j.jbtep.2020.101575

Cognitive remediation for inpatients with psychosis: a systematic review and meta-analysis

Matteo Cella, Tom Price, Holly Corboy, Juliana Onwumere, Sukhi Shergill and Antonio Preti 2020. Cognitive remediation for inpatients with psychosis: a systematic review and meta-analysis. Psychological Medicine. 50 (7), pp. 1062-1076. https://doi.org/10.1017/S0033291720000872

Examination of the neural basis of psychotic-like experiences in adolescence during processing of emotional faces

Sukhi Shergill, Evangelos Papanastasiou, Elias Mouchlianitis, Dan W. Joyce, Philip McGuire, Celia Boussebaa, Tobias Banaschewski, Arun L. W. Bokde, Christian Büchel, Erin Quinlan, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Philip Spechler, Penny Gowland, Andreas Heinz, Bernd Ittermann, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Sabina Millenet, Juliane H. Fröhner, Michael N. Smolka, Henrik Walter, Robert Whelan, Gunter Schumann and Sukhwinder S. Shergill 2020. Examination of the neural basis of psychotic-like experiences in adolescence during processing of emotional faces. Scientific Reports. 10, p. 5164. https://doi.org/10.1038/s41598-020-62026-7

Why care about integrated care? Part I. Demographics, finances and workforce: immovable objects facing mental health services

Tracy, D. K., Holloway, F., Hanson, K., James, A., Strathdee, G., Holmes, D., Kalidini, S. and Shergill, S. 2020. Why care about integrated care? Part I. Demographics, finances and workforce: immovable objects facing mental health services. BJPsych Advances. 29 (1), pp. 8-18. https://doi.org/10.1192/bja.2019.78

Why care about integrated care? Part 2. Integrated care systems: an irresistible force changing mental health services

Tracy, D. K., Holloway, F., Hanson, K., Kanani, N., Trainer, M., Dimond, I., James, A., Kalidini, S. and Shergill, S. 2020. Why care about integrated care? Part 2. Integrated care systems: an irresistible force changing mental health services. BJPsych Advances. 29 (1), pp. 19-30. https://doi.org/10.1192/bja.2020.3

In the eye of the beholder? Oxytocin effects on eye movements in schizophrenia

Lilla A. Porffy, Victoria Bell, Antoine Coutrot, Rebekah Wigton, Teresa D'Oliveira, Isabelle Mareschal and Sukhwinder S. Shergill 2020. In the eye of the beholder? Oxytocin effects on eye movements in schizophrenia. Schizophrenia Research. 216, pp. 279-287.

Schizophrenia polygenic risk score influence on white matter microstructure

Beatriz Simões, Evangelos Vassos, Sukhi Shergill, Colm McDonald, Timothea Toulopoulou, Sridevi Kalidindi, Fergus Kane, Robin Murray, Elvira Bramon, Hugo Ferreira and Diana Prata 2020. Schizophrenia polygenic risk score influence on white matter microstructure. Journal of Psychiatric Research. 121, pp. 62-67. https://doi.org/10.1016/j.jpsychires.2019.11.011

Neural correlates of positive and negative symptoms through the illness course: an fMRI study in early psychosis and chronic schizophrenia

Lucy D. Vanes, Elias Mouchlianitis, Krisna Patel, Erica Barry, Katie Wong, Megan Thomas, Timea Szentgyorgyi, Dan Joyce and Sukhwinder Shergill 2019. Neural correlates of positive and negative symptoms through the illness course: an fMRI study in early psychosis and chronic schizophrenia. Scientific Reports. 9, p. 14444. https://doi.org/10.1038/s41598-019-51023-0

Real-world outcomes in the management of refractory psychosis

Amir Krivoy, Dan Joyce, Derek Tracy, Fiona Gaughran, James MacCabe, John Lally, Eromona Whiskey, S. Neil Sarkar and Sukhwinder S. Shergill 2019. Real-world outcomes in the management of refractory psychosis. Journal of Clinical Psychiatry. 80 (5), p. 18m12716. https://doi.org/10.4088/JCP.18m12716

Understanding and managing cardiac side-effects of second-generation antipsychotics in the treatment of schizophrenia

Mark Sweeney, Eromona Whiskey, Rishi K. Patel, Derek K. Tracy, Sukhi S. Shergill and Carla M. Plymen 2019. Understanding and managing cardiac side-effects of second-generation antipsychotics in the treatment of schizophrenia. BJPsych Advances. 26 (1), pp. 26-40. https://doi.org/10.1192/bja.2019.49

Clozapine and cardiotoxicity – A guide for psychiatrists written by cardiologists

Rishi K. Patel, Alice M. Moore, Susan Piper, Mark Sweeney, Eromona Whiskey, Graham Cole, Suhki Shergill and Carla M. Plymen 2019. Clozapine and cardiotoxicity – A guide for psychiatrists written by cardiologists. Psychiatry Research. 282, p. 112491. https://doi.org/10.1016/j.psychres.2019.112491

Girls-boys: an investigation of gender differences in the behavioral and neural mechanisms of trust and reciprocity in adolescence

Imke L. J. Lemmers-Jansen, Anne-Kathrin J. Fett, Sukhi Shergill, Marlieke T. R. van Kesteren and Lydia Krabbendam 2017. Girls-boys: an investigation of gender differences in the behavioral and neural mechanisms of trust and reciprocity in adolescence. Frontiers in Human Neuroscience. 13 (257).

Integrated care in mental health: Next steps after the NHS Long Term Plan

Derek K. Tracy, Kara Hanson, Tom Brown, Adrian J. B. James, Holly Paulsen, Zoé Mulliez and Sukhwinder Shergill 2019. Integrated care in mental health: Next steps after the NHS Long Term Plan. British Journal of Psychiatry. 214 (6), pp. 315-317. https://doi.org/10.1192/bjp.2019.46

Cognitive correlates of abnormal myelination in psychosis

Lucy D. Vanes, Elias Mouchlianitis, Erica Barry, Krisna Patel, Katie Wong and Sukhwinder S. Shergill. 2019. Cognitive correlates of abnormal myelination in psychosis. Scientific Reports. 9 (5162). https://doi.org/10.1038/s41598-019-41679-z

Dopamine manipulations drive changes in information sampling in healthy volunteers

Shergill, S. 2019. Dopamine manipulations drive changes in information sampling in healthy volunteers. Journal of Psychopharmacology. 33 (6), pp. 670-677. https://doi.org/10.1177/0269881118822080
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