Kent and Medway Medical School (KMMS)


Latest research outputs

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Stage 3 N2 lung cancer: A multidisciplinary therapeutic conundrum
Lily Carter, Vedika Apte, Arushi Shukla, Aruni Ghose, Raj Mamidi, Alexandra Petohazi, Shania Makker, Soirindhri Banerjee, Stergios Boussios and Giuseppe L. Banna 2024. Stage 3 N2 lung cancer: A multidisciplinary therapeutic conundrum. Current Oncology Reports. 26, pp. 65-79.

Journal article

Exploring Health Care Disparities in Genetic Testing and Research for Hereditary Cardiomyopathy: Current State and Future Perspectives.
Huang, Helen, Verma, Jay, Mok, Valerie, Bharadwaj, Hareesha R, Alrawashdeh, Maen M, Aratikatla, Adarsh, Sudan, Sourav, Talukder, Suprateeka, Habaka, Minatoullah, Tse, Gary and Bardhan, M. 2024. Exploring Health Care Disparities in Genetic Testing and Research for Hereditary Cardiomyopathy: Current State and Future Perspectives. Global Medical Genetics. 11 (1), pp. 36-47. https://doi.org/10.1055/s-0044-1779469

Journal article

Electrocardiographic characteristics of bladder cancer patients receiving preoperative chemotherapy combined with immunotherapy.
Chen, Zi-Liang, Jia, Kai-Peng, Zheng, Yi, Zhang, Nan, Wang, Xin, Tse, Gary, Zhang, Zhi-Wei, Hu, Hai-Long and Liu, T. 2024. Electrocardiographic characteristics of bladder cancer patients receiving preoperative chemotherapy combined with immunotherapy. Annals of Noninvasive Electrocardiology. 29 (1), p. e13107. https://doi.org/10.1111/anec.13107

Journal article

Connectome dysfunction in patients at clinical high risk for psychosis and modulation by oxytocin
Davies, C., Martins, D., Dipasquale, O., McCutcheon, Robert A, De Micheli, Andrea, Ramella-Cravaro, Valentina, Provenzani, Umberto, Rutigliano, Grazia, Cappucciati, Marco, Oliver, D., Williams, S., Zelaya, Fernando, Allen, Paul, Murguia, Silvia, Taylor, David, Shergill, Sukhi, Morrison, Paul, McGuire, P., Paloyelis, Y. and Fusar-Poli, P. 2024. Connectome dysfunction in patients at clinical high risk for psychosis and modulation by oxytocin. Molecular Psychiatry. https://doi.org/10.1038/s41380-024-02406-x

Journal article

The psychosocial burden of cutaneous leishmaniasis in rural Sri Lanka: A multi-method qualitative study.
Nuwangi, Hasara, Dikomitis, Lisa, Weerakoon, Kosala Gayan, Agampodi, S. and Agampodi, Thilini Chanchala 2024. The psychosocial burden of cutaneous leishmaniasis in rural Sri Lanka: A multi-method qualitative study. PLoS Neglected Tropical Diseases. 18 (1), p. e0011909. https://doi.org/10.1371/journal.pntd.0011909

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Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring.
Li, L., Wu, Bin, Dong, Jiaoxuan, He, Songbin, Xu, Jie, Tse, Gary, Dai, Fangyu and Liu, H. 2024. Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring. Journal of Clinical Hypertension. 26 (2), pp. 122-133. https://doi.org/10.1111/jch.14759

Journal article

Frontiers of ovarian carcinosarcoma
Ismail, A., Choi, S. and Boussios, S. 2023. Frontiers of ovarian carcinosarcoma. Current Treatment Options in Oncology. https://doi.org/10.1007/s11864-023-01138-4

Journal article

Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness
Ping Huang, Huachao Li, Liping Ren, Haimei Xie, Liushan Chen, Yuqi Liang, Yuyu Hu, Heloisa Sobreiro Selistre-de-Araujo, Stergios Boussios, Sachin R. Jhawar, Rutao Cui, Qian Zuo and Qianjun Chen 2023. Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness. Translational Cancer Research. 12 (12).

Journal article

Statin use and mortality risk in Asian patients with prostate cancer receiving androgen deprivation therapy: A population-based cohort study
Yan Hiu Athena Lee, Jeffrey Shi Kai Chan, Jeremy Man Ho Hui, Pias Tang, Kang Liu, Edward Christopher Dee, Kenrick Ng, Tse, G. and Chi Fai Ng 2023. Statin use and mortality risk in Asian patients with prostate cancer receiving androgen deprivation therapy: A population-based cohort study. Cancer Medicine. p. e6826. https://doi.org/10.1002/cam4.6826

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Linking research to end users through community engagement: an umbrella review
Getachew Taffere, Haftom Temesgen, Binega Haileselassie, Zenawi Zerihun, Brianne Wenning, Lisa Dikomitis and Afework Mulugeta 2023. Linking research to end users through community engagement: an umbrella review. Journal of Public Health. https://doi.org/10.1007/s10389-023-02167-x

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Teaching medical anthropology in UK medical schools: cultivating autoethnographic practice among medical students
Harvey, T., Dikomitis, L. and Wenning, B. 2023. Teaching medical anthropology in UK medical schools: cultivating autoethnographic practice among medical students. Teaching Anthropology. 12 (2), pp. 53-65. https://doi.org/10.22582/ta.v12i2.695

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Equity with equality? Contextualising everyone can widen participation in medical school admissions
Chan, P., Anthony, Anna, Quinlan, Kathleen, Smith, Sharon and Holland, Chris 2023. Equity with equality? Contextualising everyone can widen participation in medical school admissions. Medical Teacher. https://doi.org/10.1080/0142159x.2023.2287982

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Cancer disparities in Southeast Asia: intersectionality and a call to action.
Feliciano, Erin Jay G, Ho, Frances Dominique V, Yee, Kaisin, Paguio, Joseph A, Eala, Michelle Ann B, Robredo, Janine Patricia G, Ng, Kenrick, Lim, Jasmine, Pyone, Khin Thuzar, Peralta, Catherine A, Flores, Jerickson Abbie, Yao, J Seth, Santos, Patricia Mae G, Ang, Christian Daniel U, Lasco, Gideon, Chan, Jeffrey Shi Kai, Tse, Gary, Tangco, Enrico D, Kingham, T Peter, Chitapanarux, Imjai, Bhoo-Pathy, Nirmala, Legaspi, Gerardo D and Dee, Edward Christopher 2023. Cancer disparities in Southeast Asia: intersectionality and a call to action. The Lancet Regional Health. Western Pacific. 41, p. 100971. https://doi.org/10.1016/j.lanwpc.2023.100971

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Hallmarks of the tumour microenvironment of gliomas and its interaction with emerging immunotherapy modalities
Christian A. Linares, Anjana Varghese, Aruni Ghose, Sayali D. Shinde, Sola Adeleke, Elisabet Sanchez, Matin Sheriff, Cyrus Chargari, Elie Rassy and Stergios Boussios 2023. Hallmarks of the tumour microenvironment of gliomas and its interaction with emerging immunotherapy modalities. International Journal of Molecular Sciences. 24 (17), p. 13215. https://doi.org/10.3390/ijms241713215

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Prognostic factors in patients with metastatic spinal cord compression secondary to lung cancer—A retrospective UK single-centre study
Anna Vassiliou, Temidayo Osunronbi, Synthia Enyioma, Gerardo Rago, Afroditi Karathanasi, Aruni Ghose, Matin Sheriff, Christos Mikropoulos, Elisabet Sanchez, Michele Moschetta, Cyrus Chargari, Elie Rassy and Stergios Boussios 2023. Prognostic factors in patients with metastatic spinal cord compression secondary to lung cancer—A retrospective UK single-centre study. Cancers. 15 (18), p. 4432. https://doi.org/10.3390/cancers15184432

Journal article

Exosomes in the diagnosis and treatment of renal cell cancer
Boussios, S., Devo, P., Goodall, Iain C A, Sirlantzis, Konstantinos, Ghose, A., Shinde, Sayali D, Papadopoulos, Vasileios, Sanchez, Elisabet, Rassy, E. and Ovsepian, Saak V 2023. Exosomes in the diagnosis and treatment of renal cell cancer. International Journal of Molecular Sciences. 24 (18), p. 14356. https://doi.org/10.3390/ijms241814356

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Developing a risk prediction tool for lung cancer in Kent and Medway, England: cohort study using linked data
David Howell, Ross Buttery, Padmanabhan Badrinath, Abraham George, Rithvik Hariprasad, Ian Vousden, Tina George and Cathy Finnis 2023. Developing a risk prediction tool for lung cancer in Kent and Medway, England: cohort study using linked data. BJC Reports. 1 (16). https://doi.org/10.1038/s44276-023-00019-5

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Initiation of warfarin is associated with decreased mortality in patients with infective endocarditis: A population-based cohort study.
Lee, Teddy Tai Loy, Chan, Sunny Ching Long, Chou, Oscar Hou In, Lee, Sharen, Chan, Jeffrey Shi Kai, Liu, Tong, Chang, Carlin, Wong, Wing Tak, Lip, Gregory Y H, Cheung, Bernard Man Yung, Wai, Abraham Ka-Chung and Tse, Gary 2023. Initiation of warfarin is associated with decreased mortality in patients with infective endocarditis: A population-based cohort study. Thrombosis Research. 233, pp. 1-9. https://doi.org/10.1016/j.thromres.2023.11.009

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Prognostic value of left atrial reverse remodelling in heart failure with preserved ejection fraction
Sun, Yuxi, Fu, Qiang, Tse, Gary, Bai, Lin, Liu, Jiani, He, Hongyan, Zhao, Shuang, Tse, Mimi and Liu, Ying 2023. Prognostic value of left atrial reverse remodelling in heart failure with preserved ejection fraction. Journal of Cardiovascular Medicine. 25 (2), pp. 132-140. https://doi.org/10.2459/jcm.0000000000001578

Journal article

Proteinuria, body mass index, and the risk of new-onset heart failure: a prospective cohort study in Northern China
Tse, G. 2023. Proteinuria, body mass index, and the risk of new-onset heart failure: a prospective cohort study in Northern China. Current Problems in Cardiology.

Journal article

Mexiletine: Antiarrhythmic mechanisms, emerging clinical applications and mortality.
Olleik, Farah, Kamareddine, Mohammed Hussein, Spears, Jenna, Tse, Gary, Liu, Tong and Yan, G. 2023. Mexiletine: Antiarrhythmic mechanisms, emerging clinical applications and mortality. Pacing and Clinical Electrophysiology. https://doi.org/10.1111/pace.14846

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The safety of digital mental health interventions: Systematic review and recommendations
Taher, R., Hsu, C., Hampshire, C., Fialho, C., Heaysman, C., Stahl, D., Shergill, S. and Yiend, J. 2023. The safety of digital mental health interventions: Systematic review and recommendations. JMIR Mental Health. 10, p. e47433. https://doi.org/10.2196/47433

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Association of late potentials with fatal arrhythmic events in patients with brugada syndrome-A meta-analysis
Bazoukis, George, Letsas, Konstantinos P, Liu, Tong, Tse, Gary and Alsheikh-Ali, Alawi 2023. Association of late potentials with fatal arrhythmic events in patients with brugada syndrome-A meta-analysis. Cardiology in Review. https://doi.org/10.1097/CRD.0000000000000511

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A-294 duplicate testing of samples suspected of SARS-CoV-2 infection could prevent misdiagnosis of Covid-19
Sánchez-Sánchez, J, Thapa, G, Mylona, A and Vuono, R 2023. A-294 duplicate testing of samples suspected of SARS-CoV-2 infection could prevent misdiagnosis of Covid-19. Clinical Chemistry. 69 (Supplement_1). https://doi.org/10.1093/clinchem/hvad097.259

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Secular trends of health care resource utilization and costs between Brugada syndrome and congenital long QT syndrome: A territory-wide study
Lee, Sharen, Chung, Cheuk To Skylar, Radford, Danny, Chou, Oscar Hou In, Lee, Teddy Tai Loy, Ng, Zita Man Wai, Roever, Leonardo, Rajan, Rajesh, Bazoukis, George, Letsas, Konstantinos P., Zeng, Shaoying, Liu, Fang Zhou, Wong, Wing Tak, Liu, Tong and Tse, Gary 2023. Secular trends of health care resource utilization and costs between Brugada syndrome and congenital long QT syndrome: A territory-wide study. Clinical Cardiology. https://doi.org/10.1002/clc.24102

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Clinical and non-clinical cardiovascular disease associated pathologies in Parkinson's disease
Bonn Lee, Charlotte Edling, Shiraz Ahmad, Fiona E. N. LeBeau, Gary Tse and Kamalan Jeevaratnam 2023. Clinical and non-clinical cardiovascular disease associated pathologies in Parkinson's disease. International Journal of Molecular Sciences. 24 (16), p. 12601.

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Associations between modifiable risk factors and frailty: a Mendelian randomisation study
Nan Zhang, Ziheng Jia, Tianshu Gu, Yi Zheng, Yunpeng Zhang, Wenhua Song, Ziliang Chen, Guangping Li, Gary Tse and Tong Liu 2023. Associations between modifiable risk factors and frailty: a Mendelian randomisation study. Journal of Epidemiology & Community Health. https://doi.org/10.1136/jech-2023-220882

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Immunotherapy for advanced urothelial carcinoma (UC): rational and current evidence
Mario Uccello, Sola Adeleke, Michele Moschetta, Aruni Ghose and Stergios Boussios 2023. Immunotherapy for advanced urothelial carcinoma (UC): rational and current evidence. Annals of Palliative Medicine. https://doi.org/10.21037/apm-22-1350

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Clinical challenges in the management of malignant ovarian germ cell tumours
Iqra Saani, Nitish Raj, Raja Sood, Shahbaz Ansari, Haider Abbas Mandviwala, Elisabet Sanchez and Stergios Boussios 2023. Clinical challenges in the management of malignant ovarian germ cell tumours. International Journal of Environmental Research and Public Health. 20 (12), p. 6089.

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Impact of COVID-19 on cancer services and patients' outcomes: a retrospective single-center study
Baijaeek Sain, Arnab Gupta, Aruni Ghose, Sudip Halder, Samir Bhattacharya, Radha Raman Mondal, Subhamoy Paul, Chandrakanth Are and Stergios Boussios 2023. Impact of COVID-19 on cancer services and patients' outcomes: a retrospective single-center study. Annals of Translational Medicine. 11 (9). https://doi.org/10.21037/atm-22-5876

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Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial
Farooq, Saeed, Sheikh, Saima, Dikomitis, Lisa, Haq Mian Mukhtar, Ul, Khan, Abdul Jalil, Sanauddin, Noor, Ali, Malik Wajid, Ali, Johar, Khan, Muhammad Firaz, Chaudhry, Imran, Husain, Nusrat, Gul, Muhammad, Irfan, Muhammad, Andrews, Gabrielle, Kaistha, Prachi, Shah, Syed Muhammad Uzair, Azeemi, Ishfaq, Hamid, Shumaila, Minhaz, Aaliya, Mallen, Christian and Lewis, Martyn 2023. Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial. BMJ Open. 13 (7), p. e072471. https://doi.org/10.1136/bmjopen-2023-072471

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Dysglycemia and arrhythmias
Sun, Dong-Kun, Zhang, Nan, Liu, Ying, Qiu, Jiu-Chun, Tse, Gary, Li, Guang-Ping, Roever, Leonardo and Liu, Tong 2023. Dysglycemia and arrhythmias. World Journal of Diabetes. 14 (8), pp. 1163-1177. https://doi.org/10.4239/wjd.v14.i8.1163

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Safeguarding community-centred global health research during crises
Agampodi, T., Nuwangi, H., Gunasekara, Sonali, Mallawaarachchi, Asitha, Price, Helen P, Dikomitis, Lisa and Agampodi, S. 2023. Safeguarding community-centred global health research during crises. BMJ global health. 8 (8), p. e013304. https://doi.org/10.1136/bmjgh-2023-013304

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Association of Life’s Essential 8 with incident atherosclerotic cardiovascular disease in cancer patients: the Kailuan prospective cohort study
Zhang, Nan, Wei, Zhihao, Zhang, Yunpeng, Zhang, Qingling, Chen, Ziliang, Tse, Gary, Li, Guangping, Liu, T. and Wu, Shouling 2023. Association of Life’s Essential 8 with incident atherosclerotic cardiovascular disease in cancer patients: the Kailuan prospective cohort study. European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwad256

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Association between serum uric acid and prostate cancer mortality in androgen deprivation therapy: A population‐based cohort study
Lee, Y., Chan, J., Leung, Chi Ho, Hui, J., Dee, E., Ng, Kenrick, Liu, Kang, Liu, T., Tse, Gary and Ng, Chi Fai 2023. Association between serum uric acid and prostate cancer mortality in androgen deprivation therapy: A population‐based cohort study. Cancer Medicine. https://doi.org/10.1002/cam4.6344

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Advances in adoptive T-cell therapy for metastatic melanoma
Das, Aparimita, Ghose, Aruni, Naicker, Kevin, Sanchez, Elisabet, Chargari, Cyrus, Rassy, Elie and Boussios, S. 2023. Advances in adoptive T-cell therapy for metastatic melanoma. Current Research in Translational Medicine. 71 (3), p. 103404. https://doi.org/10.1016/j.retram.2023.103404

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Association between psychological distress and cardiovascular health amongst cancer survivors in the United States: findings from nationally representative data
Jeffrey Shi Kai Chan, Danish Iltaf Satti, Edward Christopher Dee, Garima Sharma, Salim S Virani, Tong Liu and Gary Tse 2023. Association between psychological distress and cardiovascular health amongst cancer survivors in the United States: findings from nationally representative data . European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwad162

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Temporal trends in cardiovascular burden among patients with prostate cancer receiving androgen deprivation therapy: a population-based cohort study
Jeffrey Shi Kai Chan, Danish Iltaf Satti, Yan Hiu Athena Lee, Jeremy Man Ho Hui, Edward Christopher Dee, Kenrick Ng, Kang Liu, Gary Tse and Chi Fai Ng 2023. Temporal trends in cardiovascular burden among patients with prostate cancer receiving androgen deprivation therapy: a population-based cohort study. British Journal of Cancer. 128, pp. 2253-2260. https://doi.org/10.1038/s41416-023-02271-5

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Virtual medical research mentoring
Chan, J., Lau, Dawnie Ho Hei, King, Emma, Roever, Leonardo, Liu, Tong, Shum, Yuki Ka Ling, Ng, Kenrick, Dee, Edward Christopher, Ciobanu, Ana, Bazoukis, George, Mahmoudi, Elham, Satti, Danish Iltaf, Jeevaratnam, Kamalan, Baranchuk, Adrian and Tse, Gary 2023. Virtual medical research mentoring. The Clinical Teacher. 20 (4). https://doi.org/10.1111/tct.13598

Journal article

Predictors of ventricular arrhythmias in patients with mitral valve prolapse: A meta-analysis
Bazoukis, George, Saplaouras, Athanasios, Vlachos, Konstantinos, Mililis, Panagiotis, Letsas, Konstantinos P, Efremidis, Michael, Liu, Tong and Tse, Gary 2023. Predictors of ventricular arrhythmias in patients with mitral valve prolapse: A meta-analysis. Cardiology in Review. https://doi.org/10.1097/CRD.0000000000000577

Journal article

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