Trends of frequency, mortality and risk factors among patients admitted with stroke from 2017 to 2019 to the medical ward at Kilimanjaro Christian Medical Centre hospital: a retrospective observational study

Journal article


Baraka Moshi, Nateiya Yongolo, Sanjura Mandela Biswaro, Hans Maro, Sakanda Linus, Stefan Siebert, William Nkenguye, Emma McIntosh, Febronia Shirima, Rosalia E. Njau, Alice A. Andongolile, Manasseh Joel Mwanswila, Jo E. B. Halliday, Stefanie Krauth, Kajiru Kilonzo, Richard William Walker, Gloria August Temu and Blandina T. Mmbaga 2023. Trends of frequency, mortality and risk factors among patients admitted with stroke from 2017 to 2019 to the medical ward at Kilimanjaro Christian Medical Centre hospital: a retrospective observational study. BMJ Open. 13 (7), p. e071918. https://doi.org/10.1136/bmjopen-2023-071918
AuthorsBaraka Moshi, Nateiya Yongolo, Sanjura Mandela Biswaro, Hans Maro, Sakanda Linus, Stefan Siebert, William Nkenguye, Emma McIntosh, Febronia Shirima, Rosalia E. Njau, Alice A. Andongolile, Manasseh Joel Mwanswila, Jo E. B. Halliday, Stefanie Krauth, Kajiru Kilonzo, Richard William Walker, Gloria August Temu and Blandina T. Mmbaga
Abstract

Objective

The burden of stroke has increased in recent years worldwide, particularly in low-income and middle-income countries. In this study we aim to determine the number of stroke admissions, and associated comorbidities, at a referral hospital in Northern Tanzania.

Design

This was a retrospective observational study.

Setting The study was conducted at a tertiary referral hospital, Kilimanjaro Christian Medical Centre (KCMC), in the orthern zone of Tanzania.

Participants The study included adults aged 18 years and above, who were admitted to the medical wards from 2017 to 2019.

Outcome

The primary outcome was the proportion of patients who had a stroke admitted in the medical ward at KCMC and the secondary outcome was clinical outcome such as mortality.

Methods

We conducted a retrospective audit of medical records from 2017 to 2019 for adult patients admitted to the medical ward at KCMC. Data extracted included demographic characteristics, previous history of stroke and outcome of the admission. Factors associated with stroke were investigated using logistic regression.

Results

Among 7976 patients admitted between 2017 and 2019, 972 (12.2%) were patients who had a stroke. Trends show an increase in patients admitted with stroke over the 3 years with 222, 292 and 458 in 2017, 2018 and 2019, respectively. Of the patients who had a stroke, 568 (58.4%) had hypertension while 167 (17.2%) had diabetes mellitus. The proportion of admitted stroke patients aged 18–45 years, increased from 2017 (n=28, 3.4%) to 2019 (n=40, 4.3%). The in-hospital mortality related to stroke was 229 (23.6%) among 972 patients who had a stroke and female patients had 50% higher odds of death as compared with male patients (OR:1.5; CI 1.30 to 1.80).

Conclusion

The burden of stroke on individuals and health services is increasing over time, which reflects a lack of awareness on the cause of stroke and effective preventive measures. Prioritising interventions directed towards the reduction of non-communicable diseases and associated complications, such as stroke, is urgently needed.

KeywordsMortality; Risk factors; Stroke patients; Kilimanjaro; Tanzania
Year2023
JournalBMJ Open
Journal citation13 (7), p. e071918
PublisherBMJ Publishing Group
ISSN2044-6055
Digital Object Identifier (DOI)https://doi.org/10.1136/bmjopen-2023-071918
Official URLhttps://bmjopen.bmj.com/content/13/7/e071918
FunderNational Institute for Health and Care Research (NIHR)
Publication dates
Online31 Jul 2023
Publication process dates
Accepted18 Jun 2023
Deposited11 Jul 2024
Publisher's version
License
File Access Level
Open
Output statusPublished
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