Utilizing the second-meal effect in type 2 diabetes: practical use of a soya-yogurt snack

Journal article


Chen, M., Jovanovic, A. and Taylor, R. 2010. Utilizing the second-meal effect in type 2 diabetes: practical use of a soya-yogurt snack . Diabetes Care. 33 (12), pp. 2552-2554. https://doi.org/10.2337/dc10-0552.
AuthorsChen, M., Jovanovic, A. and Taylor, R.
Abstract

OBJECTIVE
To evaluate the effect of a prebreakfast high-protein snack upon postbreakfast hyperglycemia.

RESEARCH DESIGN AND METHODS
We studied 10 men and women with diet- and/or metformin-controlled type 2 diabetes. Metabolic changes after breakfast were compared between 2 days: breakfast taken only and soya-yogurt snack taken prior to breakfast.

RESULTS
There was a significant lower rise in plasma glucose on the snack day. The incremental area under the glucose curve was 450 ± 55 mmol · min/l on the snack day compared with 699 ± 99 mmol · min/l on the control day (P = 0.013). The concentration of plasma free fatty acids immediately before breakfast correlated with the increment in plasma glucose (r = 0.50, P = 0.013).

CONCLUSIONS
Consuming a high-protein prebreakfast snack results in almost 40% reduction of postprandial glucose increment. The second-meal effect can be applied simply and practically to improve postbreakfast hyperglycemia in people with type 2 diabetes.

KeywordsHyperglycemia; Postprandial; Second-meal effect; Type 2 diabetes
Year2010
JournalDiabetes Care
Journal citation33 (12), pp. 2552-2554
PublisherAmerican Diabetes Association
ISSN0149-5992
1935-5548
Digital Object Identifier (DOI)https://doi.org/10.2337/dc10-0552.
Official URLhttps://pubmed.ncbi.nlm.nih.gov/21115766/
FunderWellcome Trust
Publication dates
Online01 Dec 2010
Publication process dates
Accepted07 Jul 2010
Deposited17 Apr 2024
Publisher's version
License
File Access Level
Open
Output statusPublished
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