Investigating the effect of mesoporous silica nanoparticles as a drug delivery system for Withaferin A in the treatment of Lung Cancer

Conference poster

Holder, J., Wilson, C., Bertolo-Pardo, E., Byrne, L., Lodeiro, C., Oliveira, E. and Trim, C. 2024. Investigating the effect of mesoporous silica nanoparticles as a drug delivery system for Withaferin A in the treatment of Lung Cancer.
AuthorsHolder, J., Wilson, C., Bertolo-Pardo, E., Byrne, L., Lodeiro, C., Oliveira, E. and Trim, C.
TypeConference poster
Description

This was a shotgun poster.

KeywordsNanoparticles; Drug delivery; Lung cancer
Year2024
Conference6th International Caparica Symposium on Nanoparticles/Nanomaterials and Applications 2024
Related URLhttps://www.isn2a2024.com/shotgun-presentations/
Publication process dates
Deposited15 Apr 2024
Permalink -

https://repository.canterbury.ac.uk/item/9795q/investigating-the-effect-of-mesoporous-silica-nanoparticles-as-a-drug-delivery-system-for-withaferin-a-in-the-treatment-of-lung-cancer

  • 34
    total views
  • 0
    total downloads
  • 3
    views this month
  • 0
    downloads this month

Export as

Related outputs

Ammonia and temperature sensing applications using fluorometric and colorimetric microparticles and polymeric films doped with BODIPY-emitters
Bertolo, E., Beatriz S. Cugnasca, Frederico Duarte, Hugo M. Santos, José Luis Capelo-Martínez, Alcindo A. Dos Santos and Carlos Lodeiro 2024. Ammonia and temperature sensing applications using fluorometric and colorimetric microparticles and polymeric films doped with BODIPY-emitters. Microchimica Acta. 191 (746), pp. 1-18. https://doi.org/10.1007/s00604-024-06814-2
Standard operating procedure for the operation of SEM-EDX for elemental analysis, with additional applications to biomass
Hernandez, E., Thomas, J.K., Kheirandish, K., Wilson, C. and Ortega, H. 2024. Standard operating procedure for the operation of SEM-EDX for elemental analysis, with additional applications to biomass. Canterbury Christ Church University. https://doi.org/10.5281/zenodo.13736742
Differential microRNA expression in the SH-SY5Y human cell model as potential biomarkers for Huntington’s disease
Belkozhayev, Ayaz, Niyazova, Raigul, Kamal, Mohammad Amjad, Ivashchenko, Anatoliy, Sharipov, Kamalidin and Wilson, C. 2024. Differential microRNA expression in the SH-SY5Y human cell model as potential biomarkers for Huntington’s disease. Frontiers in Cellular Neuroscience. 18, p. 1399742. https://doi.org/10.3389/fncel.2024.1399742
Novel transcriptional and DNA methylation abnormalities of SORT1 Gene in non-small cell lung cancer
Acha-Sagredo, Amelia, Wilson, C., Garcia Bediaga, Naiara, Kalirai, Helen, Davies, M., Coupland, S., Field, John K and Liloglou, T. 2024. Novel transcriptional and DNA methylation abnormalities of SORT1 Gene in non-small cell lung cancer. Cancers. 16 (11), p. 2154. https://doi.org/10.3390/cancers16112154
Editorial: Targeting nucleotide metabolism for enhancing antitumor immunity.
Wu, Jun, Rong, Yu, Li, Tian, Wilson, C., He, Yazhou, Chen, Danqian, Han, Jin and Zhang, Xingmei 2024. Editorial: Targeting nucleotide metabolism for enhancing antitumor immunity. Frontiers in Immunology. 15, p. 1412057. https://doi.org/10.3389/fimmu.2024.1412057
Ion channel tools and therapeutics from venoms and toxins
Trim, C., Leffer, A.E., Samanani, Z and Trim, S. 2024. Ion channel tools and therapeutics from venoms and toxins. in: Stephens, G. and Stevens, E. (ed.) Ion Channels as Targets in Drug Discovery Cham Springer. pp. 497-534
Investigating the effect of silica nanoparticles as a drug delivery system for Doxorubicin in the treatment of lung cancer
Holder, J., Wilson, C., Bertolo-Pardo, E., Byrne, L., Oliveira, E., Lodeiro, C. and Trim, C. 2024. Investigating the effect of silica nanoparticles as a drug delivery system for Doxorubicin in the treatment of lung cancer.
AI is a viable alternative to high throughput screening: a 318-target study
Wilson, C.M., Byrne, L., Al-Yozbaki, M. and The Atomwise AIMS Program 2024. AI is a viable alternative to high throughput screening: a 318-target study. Scientific Reports. https://doi.org/10.1038/s41598-024-54655-z
Mesenchymal stem cell-derived exosomes: Characteristics and applications in disease pathology and management.
Padinharayil, H., Varghese, J., Wilson, C. and George, A. 2024. Mesenchymal stem cell-derived exosomes: Characteristics and applications in disease pathology and management. Life Sciences. 342 (122542). https://doi.org/10.1016/j.lfs.2024.122542
Overview of hepatocellular carcinoma: from molecular aspects to future therapeutic options.
Panneerselvam, S., Wilson, Cornelia, Kumar, Prem, Abirami, Dinu, Pamarthi, Jayakrishna, Reddy, Mettu Srinivas and Varghese, Joy 2023. Overview of hepatocellular carcinoma: from molecular aspects to future therapeutic options. Cell Adhesion and Migration. 17 (1), pp. 1-21. https://doi.org/10.1080/19336918.2023.2258539
The use of nanoparticles for targeted drug delivery in non-small cell lung cancer.
Holder, Jessica E, Ferguson, C., Oliveira, Elisabete, Lodeiro, Carlos, Trim, Carol M, Byrne, Lee J, Bertolo, Emilia and Wilson, Cornelia M 2023. The use of nanoparticles for targeted drug delivery in non-small cell lung cancer. Frontiers in Oncology. 13, p. 1154318. https://doi.org/10.3389/fonc.2023.1154318
The role of nanotechnology for diagnostic and therapy strategies in lung cancer
Holder, J., Wilson, C. and Al-Yozbaki, M. 2022. The role of nanotechnology for diagnostic and therapy strategies in lung cancer. in: Jeremić, B. (ed.) Advances in Radiation Oncology in Lung Cancer Cham Springer.
Purified venom components inhibit EGFR phosphorylation in triple negative breast cancer
Mccullough, D., Baker, S., Trim, S. and Trim, C. 2022. Purified venom components inhibit EGFR phosphorylation in triple negative breast cancer.
Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics.
Padinharayil, Hafiza, Varghese, Jinsu, John, Mithun Chacko, Rajanikant, Golgodu Krishnamurthy, Wilson, Cornelia M, Al-Yozbaki, Minnatallah, Renu, Kaviyarasi, Dewanjee, Saikat, Sanyal, Rupa, Dey, Abhijit, Mukherjee, Anirban Goutam, Wanjari, Uddesh Ramesh, Gopalakrishnan, Abilash Valsala and George, Alex 2022. Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics. Genes & Diseases. 10 (3), pp. 960-989. https://doi.org/10.1016/j.gendis.2022.07.023
The role of nanotechnology for diagnostic and therapy strategies in lung cancer
Holder, J., Al-Yozbaki, M. and Wilson, C. 2022. The role of nanotechnology for diagnostic and therapy strategies in lung cancer. in: Medical Radiology Berlin, Heidelberg Springer. pp. 1-18
Advances in the lung cancer immunotherapy approaches
Padinharayil, H., Alappat, R., Joy, Liji Maria, Anilkumar, K., Wilson, C., George, A., Valsala Gopalakrishnan, A., Madhyastha, H., Ramesh, Thiyagarajan, Sathiyamoorthi, Ezhaveni, Lee, Jintae and Ganesan, R. 2022. Advances in the lung cancer immunotherapy approaches. Vaccines. 10 (11), p. 1963. https://doi.org/10.3390/vaccines10111963
Proteomic analysis of the extracellular vesicles derived from human hip joints affected by osteoarthritis
Tirnoveanu, A., Ahmed, S., Webb, R., Howland, K., Hurt, A., Wilson, C. and Mylona, A. 2022. Proteomic analysis of the extracellular vesicles derived from human hip joints affected by osteoarthritis.
Bacterial adaptation to venom in snakes and arachnida
Esmaeilishirazifard, Elham, Usher, Louise, Trim, Carol, Denise, Hubert, Sangal, V., Tyson, G., Barlow, Axel, Redway, Keith F., Taylor, John D., Kremyda-Vlachou, Myrto, Davies, Sam, Loftus, Teresa D., Lock, Mikaella M. G., Wright, Kstir, Dalby, Andrew, Snyder, L., Wuster, Wolfgang, Trim, Steve and Moschos, S. 2022. Bacterial adaptation to venom in snakes and arachnida. Microbiology Spectrum. p. e0240821. https://doi.org/10.1128/spectrum.02408-21
Bioinformatics analysis of the interaction of miRNAs and piRNAs with human mRNA genes having di- and Trinucleotide repeats
Belkozhayev, A., Niyazova, Raigul, Wilson, C., Jainakbayev, Nurlan, Pyrkova, A., Ashirbekov, Y., Akimniyazova, A., Sharipov, K. and Ivashchenko, A. 2022. Bioinformatics analysis of the interaction of miRNAs and piRNAs with human mRNA genes having di- and Trinucleotide repeats. Genes. 13 (5), p. 800. https://doi.org/10.3390/genes13050800
Stochastic variation in DNA methylation modulates nucleosome occupancy and alternative splicing in Arabidopsis thaliana
Jabre, Ibtissam, Chaudhary, S., Wilson, C., Staiger, D. and Syed, N. 2022. Stochastic variation in DNA methylation modulates nucleosome occupancy and alternative splicing in Arabidopsis thaliana. Plants. 11 (9), p. 1105. https://doi.org/10.3390/plants11091105
Development of low-cost colourimetric and pH sensors based on PMMA@Cyanine polymers
Galhano, J., Marcelo, Gonçalo A., Kurutos, A., Bértolo, Emilia, Capelo-Martinez, Jose Luis, Lodeiro, Carlos and Oliveira, E. 2022. Development of low-cost colourimetric and pH sensors based on PMMA@Cyanine polymers. Dyes and Pigments. 200, p. 110154. https://doi.org/10.1016/j.dyepig.2022.110154
Extracellular vesicles, stem cells and the role of miRNAs in neurodegeneration
Belkozhayev, Ayaz M., Al-Yozbaki, Minnatallah, George, Alex, Ye Niyazova, Raigul, Sharipov, Kamalidin O., Byrne, Lee J. and Wilson, Cornelia M. 2021. Extracellular vesicles, stem cells and the role of miRNAs in neurodegeneration. Current Neuropharmacology. 20 (8), pp. 1450-1478. https://doi.org/10.2174/1570159x19666210817150141
Exploring the cytotoxic mechanisms of Pediocin PA-1 towards HeLa and HT29 cells by comparison to known bacteriocins: Microcin E492, enterocin heterodimer and Divercin V41.
Buss, G. and Wilson, C. 2021. Exploring the cytotoxic mechanisms of Pediocin PA-1 towards HeLa and HT29 cells by comparison to known bacteriocins: Microcin E492, enterocin heterodimer and Divercin V41. PLoS ONE. 16 (9), p. e0251951. https://doi.org/10.1371/journal.pone.0251951
The undiscovered potential of essential oils for treating SARS-CoV-2 (COVID-19)
Wilkin, P. J., Al-Yozbaki, M., George, A., Gupta, G.K. and Wilson, C.M. 2021. The undiscovered potential of essential oils for treating SARS-CoV-2 (COVID-19). Current Pharmaceutical Design. 26 (41), pp. 5261-5277. https://doi.org/10.2174/1381612826666201015154611
Balancing neurotrophin pathway and sortilin function: its role in human disease
Al-Yozbaki, M., Acha-Sagredo, A., George, A., Liloglou, T. and Wilson, C.M. 2021. Balancing neurotrophin pathway and sortilin function: its role in human disease. Biochim Biophys Acta Rev Cancer. 1874 (2). https://doi.org/10.1016/j.bbcan.2020.188429
Targeting DNA methyltransferases in non-small-cell lung cancer
Al-Yozbaki, M., Jabre, I., Syed, N. and Wilson, C. 2021. Targeting DNA methyltransferases in non-small-cell lung cancer. Seminars in Cancer Biology. https://doi.org/10.1016/j.semcancer.2021.01.005
Therapeutic potential of natural compounds in lung cancer
Al-Yozbaki, M., Wilkin, P., Gupta, G. and Wilson, C. 2021. Therapeutic potential of natural compounds in lung cancer. Current Medicinal Chemistry. 28 (39), pp. 7988-8002. https://doi.org/10.2174/0929867328666210322103906
Utilisation of compounds from venoms in drug discovery
Trim, Carol M, Byrne, Lee J and Trim, Steven A 2021. Utilisation of compounds from venoms in drug discovery. Progress in Medicinal Chemistry. 60, pp. 1-66. https://doi.org/S0079-6468(21)00001-1
Powerful proteins from polyp possessing predators
Robinson P.J., Trim, S.A. and Trim, C.M. 2021. Powerful proteins from polyp possessing predators. in: Mariottini, G.L., Killi, N. and Xiao, L. (ed.) The Cnidaria: only a problem or also a source Nova Science Publishers.
Beauty from the deep: cnidarians in cosmetics
Trim, S.A., Wandrey, F and Trim, C.M. 2021. Beauty from the deep: cnidarians in cosmetics. in: Mariottini, G.L., Killi, N. and Xiao, L. (ed.) The Cnidaria: Only a problem or also a source Nova Science Publishers.
Full spectrum lighting induces behavioral changes and increases cortisol immunoreactivity in captive arachnids
Somerville, S., Baker, S., Baines, F., Trim, S. and Trim, C.M. 2020. Full spectrum lighting induces behavioral changes and increases cortisol immunoreactivity in captive arachnids. Journal of Applied Animal Welfare Science. 24 (2), pp. 132-148. https://doi.org/10.1080/10888705.2021.1872027
The failures of ethnobotany and phytomedicine in delivering novel treatments for snakebite envenomation
Trim, S., Trim, C., Williams, H. F. and Vaiyapuri, S. 2020. The failures of ethnobotany and phytomedicine in delivering novel treatments for snakebite envenomation. Toxins. 12 (12). https://doi.org/10.3390/toxins12120774
Study and preparation of Multifunctional Poly(L-Lysine)@Hyaluronic Acid Nanopolyplexes for the effective delivery of tumor suppressive MiR-34a into triple-negative breast cancer cells
Djafari, J, Fernández-Lodeiro, J., Santos, H.M., Lorenzo, J., Rodriguez-Calado, S., Bertolo-Pardo, E., Capelo-Martínez, J.L. and Lodeiro, C 2020. Study and preparation of Multifunctional Poly(L-Lysine)@Hyaluronic Acid Nanopolyplexes for the effective delivery of tumor suppressive MiR-34a into triple-negative breast cancer cells. Materials. 13 (23), p. 5309. https://doi.org/10.3390/ma13235309
Differential nucleosome occupancy modulates alternative splicing in Arabidopsis thaliana
Jabre, I., Chaudhary, S., Guo, W., Kalyna, M., Reddy, A. S. N., Chen, W., Zhang, R., Wilson, C. and Syed, N. 2020. Differential nucleosome occupancy modulates alternative splicing in Arabidopsis thaliana. New Phytologist. https://doi.org/10.1111/nph.17062
Kinome scale profiling of venom effects on cancer cells reveals potential new venom activities
Mccullough, D., Atofanei, C., Knight, E., Trim, S. and Trim, C.M. 2020. Kinome scale profiling of venom effects on cancer cells reveals potential new venom activities. Toxicon. 185, pp. 129-146. https://doi.org/10.1016/j.toxicon.2020.07.007
Applications and strategies in nanodiagnosis and nanotherapy in lung cancer
Woodman, C., Vundu, G., George, A. and Wilson, C. 2020. Applications and strategies in nanodiagnosis and nanotherapy in lung cancer. Seminars in Cancer Biology. https://doi.org/10.1016/j.semcancer.2020.02.009
Microbial adaptation to venom is common in snakes and spiders
Esmaeilishirazifard, E., Usher, L., Trim, C., Denise, H., Sangal, V., Tyson, G., Barlow, A., Redway, K., Taylor, J., Kremyda-Vlachou, M., Loftus, T., Lock, M., Wright, K., Dalby, A., Snyder, L., Wuster, W., Trim, S. and Moschos, S. 2018. Microbial adaptation to venom is common in snakes and spiders. bioRxiv. https://doi.org/10.1101/348433v1
Does co-transcriptional regulation of alternative splicing mediate plant stress responses?
Jabre, I., Reddy, A., Kalyna, M., Chaudhary, S., Khokhar, W., Byrne, L., Wilson, C. and Syed, N. 2019. Does co-transcriptional regulation of alternative splicing mediate plant stress responses? Nucleic Acids Research. 47 (6), pp. 2716-2726. https://doi.org/10.1093/nar/gkz121
Alternative splicing and protein diversity: plants versus animals
Chaudhry, S., Khokhar, W., Jabre, I., Reddy, A., Byrne, L., Wilson, C. and Syed, N. 2019. Alternative splicing and protein diversity: plants versus animals. Frontiers in Plant Science. 10 (708). https://doi.org/10.3389/fpls.2019.00708
Integrating research and knowledge exchange in the Science Undergraduate Curriculum: embedding employability through research-involved teaching
Harvey, C., Bertolo-Pardo, E. and Byrne, L. 2017. Integrating research and knowledge exchange in the Science Undergraduate Curriculum: embedding employability through research-involved teaching. in: Renes, S. (ed.) Global Voices in Higher Education In-Tech. pp. 111-128
Transitioning novel peptide hits into lead compounds
Trim, S. and Trim, C. 2019. Transitioning novel peptide hits into lead compounds. Drug Target Review. (4).
Non-invasive extraction of Cnidarian venom through the use of autotomised tentacles
Robinson, P., Trim, S. and Trim, C. 2019. Non-invasive extraction of Cnidarian venom through the use of autotomised tentacles. Animal Technology and Welfare. 18 (3).
Genome-wide identification of splicing quantitative trait loci (sQTLs) in diverse ecotypes of Arabidopsis thaliana
Khokhar, W., Hassan, M., Reddy, A., Chaudhary, S., Jabre, I., Byrne, L. and Syed, N. 2019. Genome-wide identification of splicing quantitative trait loci (sQTLs) in diverse ecotypes of Arabidopsis thaliana. Frontiers in Plant Science. 10 (1160). https://doi.org/10.3389/fpls.2019.01160
Synthesis of gold functionalised nanoparticles with the eranthis hyemalis lectin and preliminary toxicological studies on caenorhabditis elegans
Djafari, J., McConnell, M., Santos, H., Capelo, J., Bertolo-Pardo, E., Harvey, S., Lodeiro, C. and Fernández-Lodeiro, J. 2018. Synthesis of gold functionalised nanoparticles with the eranthis hyemalis lectin and preliminary toxicological studies on caenorhabditis elegans. Materials. 11 (8). https://doi.org/10.3390/ma11081363
Green and red fluorescent dyes for translational applications in imaging and sensing analytes: a dual-color flag
Oliveira, E., Bertolo-Pardo, E., Núñez, C., Pilla, V., Santos, H., Fernández-Lodeiro, J., Fernández-Lodeiro, A., Djafari, J., Capelo, J. and Lodeiro, C. 2017. Green and red fluorescent dyes for translational applications in imaging and sensing analytes: a dual-color flag. ChemistryOpen. https://doi.org/10.1002/open.201700135
‘Something in the way she moves’: The functional significance of flexibility in the multiple roles of protein disulfide isomerase (PDI)
Freedman, R., Desmond, J., Byrne, L., Heal, J., Howard, M., Sanghera, N., Walker, K., Wallis, A., Wells, S., Williamson, R. and Romer, R. 2017. ‘Something in the way she moves’: The functional significance of flexibility in the multiple roles of protein disulfide isomerase (PDI). Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1865 (11 (A)), pp. 1383-1394. https://doi.org/10.1016/j.bbapap.2017.08.014
Unraveling the organotellurium chemistry applied to the synthesis of gold nanomaterials
Fernández-Lodeiro, A., Rodriguez-Gonzales, B., Santos, H., Bertolo-Pardo, E., Capelo, J., Dos Santos, A. and Lodeiro, C. 2016. Unraveling the organotellurium chemistry applied to the synthesis of gold nanomaterials. ACS Omega. 1 (6), pp. 1314-1325. https://doi.org/10.1021/acsomega.6b00309
The role of endoproteolytic processing in neurodegeneration
Wilson, C., Mushtaq, G., Kamal, M. and Terro, F. 2016. The role of endoproteolytic processing in neurodegeneration. CNS and Neurological Disorders Drug Targets. 15. https://doi.org/10.2174/1871527315666160922163511
Challenges and strategies in precision medicine for non-small cell lung cancer
Wilson, C., Al-Akhrass, A. and Sacco, J. 2016. Challenges and strategies in precision medicine for non-small cell lung cancer. Current Pharmaceutical Design. 22. https://doi.org/10.2174/1381612822666160603014932
Winter Aconite (Eranthis hyemalis) Lectin as a cytotoxic effector in the lifecycle of Caenorhabditis elegans
McConnell, M., Lisgarten, D., Byrne, L., Harvey, S. and Bertolo-Pardo, E. 2015. Winter Aconite (Eranthis hyemalis) Lectin as a cytotoxic effector in the lifecycle of Caenorhabditis elegans. PeerJ. https://doi.org/10.7717/peerj.1206
Rapid method for targeted cell (line) selection
Lang, D., Martin, E., Montague, G., O'Malley, C., Root, T., Trim, C., Povey, J., Smales, C. and Racher, A. 2012. Rapid method for targeted cell (line) selection.
Localisation of Neuregulin 1-β3 to different sub-nuclear structures alters gene expression
Wang, M., Trim, C. and Gullick, W. 2011. Localisation of Neuregulin 1-β3 to different sub-nuclear structures alters gene expression. Experimental Cell Research. 317 (4), pp. 423-432. https://doi.org/10.1016/j.yexcr.2010.11.009.
Venom: The sharp end of pain therapy
Trim, S. and Trim, C. 2013. Venom: The sharp end of pain therapy. British Journal of Pain. 7 (4), pp. 179-188. https://doi.org/10.1177/2049463713502005
Novel approaches to targeting protein tyrosine kinases
McCullough, D. and Trim, C. 2015. Novel approaches to targeting protein tyrosine kinases. Drug Target Review.
Rapid high-throughput characterisation, classification and selection of recombinant mammalian cell line phenotypes using intact cell MALDI-ToF mass spectrometry fingerprinting and PLS-DA modelling
Povey, J., O'Malley, C., Root, T., Martin, E., Montague, G., Feary, M., Trim, C., Lang, D., Aldread, R., Racher, A. and Smales, C. 2014. Rapid high-throughput characterisation, classification and selection of recombinant mammalian cell line phenotypes using intact cell MALDI-ToF mass spectrometry fingerprinting and PLS-DA modelling. Journal of Biotechnology. 184, pp. 84-93. https://doi.org/10.1016/j.jbiotec.2014.04.028
Custom developed software to simulate the use of UV/Vis spectroscopy in quantitative chemical analysis
Bertolo-Pardo, E. and Clay, S. 2015. Custom developed software to simulate the use of UV/Vis spectroscopy in quantitative chemical analysis. in: Carmo, M. (ed.) Education Applications & Developments Lisbon InScience Press.
Cell division is essential for elimination of the yeast [PSI+] prion by guanidine hydrochloride
Byrne, L., Cox, B., Coleman, D., Ridout, M., Morgan, B. and Tuiteq, M. 2007. Cell division is essential for elimination of the yeast [PSI+] prion by guanidine hydrochloride. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 104 (28), pp. 11688-11693. https://doi.org/10.1073/pnas.0701392104
Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors
Wilson, C., Naves, T., Vincent, F., Lalloue, F. and Jauberteau, M. 2015. Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors.
Novel chromogenic macrocyclic molecular probes with logic gate function using anion/cation inputs
García, V., Fernández-Lodeiro, A., Lamelas, R., Macias, A., Bastida, R., Bertolo-Pardo, E. and Nuñez, C. 2014. Novel chromogenic macrocyclic molecular probes with logic gate function using anion/cation inputs. Dyes and Pigments. 110, pp. 143-151. https://doi.org/10.1016/j.dyepig.2014.04.023
Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors.
Wilson, C., Naves, T., Vincent, F., Melloni, B., Bonnaud, F., Lalloue, F. and Jauberteau, M. 2014. Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors. Journal of Cell Science (JCS). 127 (18), pp. 3983-3997. https://doi.org/10.1242/jcs.149336
Steady-state and time-resolved investigations on pyrene-based chemosensors
Fernández-Lodeiro, J., Nuñez, C., Castro, C., Bertolo-Pardo, E., Seixas de Melo, J., Capelo, J. and Lodeiro, C. 2013. Steady-state and time-resolved investigations on pyrene-based chemosensors. Inorganic Chemistry. 52 (1), pp. 121-129. https://doi.org/10.1021/ic301365y
The number and transmission of [PSI+] prion seeds (Propagons) in the yeast Saccharomyces cerevisiae
Byrne, L., Cole, D., Cox, B., Ridout, M., Morgan, B. and Tuite, M. 2009. The number and transmission of [PSI+] prion seeds (Propagons) in the yeast Saccharomyces cerevisiae. PLoS ONE. 4 (3), p. e4670. https://doi.org/10.1371/journal.pone.0004670
Mapping of the ligand-binding site on the b′ domain of human PDI: interaction with peptide ligands and the x-linker region
Byrne, L., Sidhu, A., Wallis, A., Ruddock, L., Freedman, R., Howard, M. and Williamson, R. 2009. Mapping of the ligand-binding site on the b′ domain of human PDI: interaction with peptide ligands and the x-linker region. Biochemical Journal. 423 (2), pp. 209-217. https://doi.org/10.1042/BJ20090565
The ligand-binding b' domain of human protein disulphide-isomerase mediates homodimerization
Wallis, A., Sidhu, A., Byrne, L., Howard, M., Ruddock, L., Williamson, R. and Freedman, R. 2009. The ligand-binding b' domain of human protein disulphide-isomerase mediates homodimerization. Protein Science. 18 (12), pp. 2569-2577. https://doi.org/10.1002/pro.270
Lanthanide(III) complexes of two novel N304-donor macrocycles derived from 3,6-Dioxa-1,8-Octanediamine
Bertolo-Pardo, E., Bastida, R., Lodeiro, C. and Rodriguez, A. 2004. Lanthanide(III) complexes of two novel N304-donor macrocycles derived from 3,6-Dioxa-1,8-Octanediamine. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 48 (3-4), pp. 151-155. https://doi.org/10.1023/B:JIPH.0000022532.55611.86
Feedback and feed forward: using video podcast to provide student feedback on past examinations and as revision aids
Bertolo-Pardo, E., Jones, P. and Carlton, K. 2012. Feedback and feed forward: using video podcast to provide student feedback on past examinations and as revision aids.
A distributed systems approach to undergraduate assessment
Bertolo-Pardo, E. and Harvey, S. 2011. A distributed systems approach to undergraduate assessment.
Enhancing the teaching-research nexus in the undergraduate curriculum through assessment
Bertolo-Pardo, E., Capelo, J., Harvey, S. and Lodeiro, C. 2012. Enhancing the teaching-research nexus in the undergraduate curriculum through assessment.
Extraction and purification of the lectin found in the tubers of Eranthis hyemalis (winter aconite)
Bertolo-Pardo, E., George, O., Solscheid, C., Fell, J. and Lisgarten, D. 2011. Extraction and purification of the lectin found in the tubers of Eranthis hyemalis (winter aconite). Journal of Integrated OMICS. 1 (2), pp. 268-272. https://doi.org/10.5584/jiomics.v1i2.72
N1-Benzylidene-N2-(2-((2-((2-(benzylideneamino)ethyl)amino)ethyl)amino)ethyl)ethane-1,2-diamine
Fernández-Lodeiro, J., Nuñez, C., Bertolo-Pardo, E., Capelo, J. and Lodeiro, C. 2012. N1-Benzylidene-N2-(2-((2-((2-(benzylideneamino)ethyl)amino)ethyl)amino)ethyl)ethane-1,2-diamine. Molbank. 2012 (4). https://doi.org/10.3390/M779
N1-((1H-Indazol-5-yl)methylene)-N2-(2-((2-((2-(((1H-indazol-6-yl)methylene)amino)ethyl)amino)ethyl)amino)ethyl)ethane-1,2-diamine
Nuñez, C., Fernández-Lodeiro, J., Fernández-Lodeiro, A., Bertolo-Pardo, E., Capelo, J. and Lodeiro, C. 2012. N1-((1H-Indazol-5-yl)methylene)-N2-(2-((2-((2-(((1H-indazol-6-yl)methylene)amino)ethyl)amino)ethyl)amino)ethyl)ethane-1,2-diamine. Molbank. 2012 (3). https://doi.org/10.3390/M770
N1-(Benzo[b]thiophen-3-ylmethylidene)-N2-(2-((2-((2-(benzo[b]thiophen-3-ylmethylidene)amino)ethyl)amino)ethyl)amino)ethyl)ethane-1,2-diamine
Nuñez, C., Fernández-Lodeiro, J., Fernández-Lodeiro, A., Bertolo-Pardo, E., Capelo, J. and Lodeiro, C. 2012. N1-(Benzo[b]thiophen-3-ylmethylidene)-N2-(2-((2-((2-(benzo[b]thiophen-3-ylmethylidene)amino)ethyl)amino)ethyl)amino)ethyl)ethane-1,2-diamine. Molbank. 2012 (3). https://doi.org/10.3390/M768
Using e-learning to support the development of an undergraduate research culture in sciences
Bertolo-Pardo, E. and Carlton, K. 2008. Using e-learning to support the development of an undergraduate research culture in sciences.
Extraction and purification of Eranthis hyemalis (Winter aconite) tuber lectin using thiourea as an antioxidant
Bertolo-Pardo, E., George, O., Lisgarten, D. and Fell, J. 2009. Extraction and purification of Eranthis hyemalis (Winter aconite) tuber lectin using thiourea as an antioxidant.
Using a Virtual Learning Environment (VLE) to support undergraduate research in sciences
Bertolo-Pardo, E. 2009. Using a Virtual Learning Environment (VLE) to support undergraduate research in sciences.
Improving extraction and purification methods of tuber lectin from winter aconite (Eranthis hyemalis)
Ponsonby, D., Solscheid, C., Fell, J., Lisgarten, D. and Bertolo-Pardo, E. 2007. Improving extraction and purification methods of tuber lectin from winter aconite (Eranthis hyemalis).
Using computer aided assessment for summative assessment: Engaging non-science students with chemistry
Bertolo-Pardo, E. and Lambert, G. 2008. Using computer aided assessment for summative assessment: Engaging non-science students with chemistry.
Focused ultrasound as an efficient methodology for the fast release of mercury from organomercurials in human urine
Bertolo-Pardo, E., Capelo, J., Oliveira, E. and Lodeiro, C. 2007. Focused ultrasound as an efficient methodology for the fast release of mercury from organomercurials in human urine.
Sensing metal ions with two new azomethine-thiophene pincer ligands (NSN): fluorescence and MALDI-TOF MS applications
Bertolo-Pardo, E., Santos, H., Pedras, B., Fernandes, L., Capelo, J., Aviles, T. and Lodeiro, C. 2007. Sensing metal ions with two new azomethine-thiophene pincer ligands (NSN): fluorescence and MALDI-TOF MS applications.
Synthesis, characterisation and metal ion sensing effect of two new flexible ligands derived from 2-hydroxy-1-naphthaldehyde
Bertolo-Pardo, E., Fernández-Lodeiro, J., Pedras, B., Capelo, J., Boucher, M. and Lodeiro, C. 2007. Synthesis, characterisation and metal ion sensing effect of two new flexible ligands derived from 2-hydroxy-1-naphthaldehyde.
Implementing computer aided assessment in chemistry: a case study
Bertolo-Pardo, E. and Lambert, G. 2007. Implementing computer aided assessment in chemistry: a case study.
Four novel N3O4 donor macrocycles and their Lanthanide(III) complexes
Bertolo-Pardo, E., Bastida, R., De Blas, A., Fenton, D., Macias, A., Rodriguez, A., Rodriguez-Blas, T. and Villar, Z. 1998. Four novel N3O4 donor macrocycles and their Lanthanide(III) complexes. Zeitschrift für Naturforschung. 53b (12), pp. 1445-1454.
Lanthanide(III) nitrate complexes of two 17 membered N3O2-donor macrocycles
Bertolo-Pardo, E., Bastida, R., De Blas, A., Fenton, D., Lodeiro, C., Macias, A., Rodriguez, A. and Rodriguez-Blas, T. 1999. Lanthanide(III) nitrate complexes of two 17 membered N3O2-donor macrocycles. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 35 (1/2), pp. 191-198. https://doi.org/10.1023/A:1008182512371
Lanthanide(III) perchlorate complexes of two 24 membered N3O4-donor macrocycles
Bertolo-Pardo, E., Bastida, R., Fenton, D., Lodeiro, C., Macias, A. and Rodriguez, A. 2001. Lanthanide(III) perchlorate complexes of two 24 membered N3O4-donor macrocycles. Journal of Alloys and Compounds. 323-4, pp. 155-158. https://doi.org/10.1016/S0925-8388(01)01109-4
Synthesis of four novel pendant armed macrocyclic ligands and their interaction with lanthanide(III) cations
Bertolo-Pardo, E., Lodeiro, C. and Bastida, R. 2006. Synthesis of four novel pendant armed macrocyclic ligands and their interaction with lanthanide(III) cations. Russian Journal of Coordination Chemistry. 32 (12), pp. 895-900. https://doi.org/10.1134/S1070328406120074
Preliminary results on the analysis of volatile and non-volatile pheromones in Chilocorus nigritus by GC/MS
Burman, J., Bertolo-Pardo, E., Capelo, J. and Ponsonby, D. 2010. Preliminary results on the analysis of volatile and non-volatile pheromones in Chilocorus nigritus by GC/MS. Electronic Journal of Environmental, Agricultural and Food Chemistry. 9 (7), pp. 1274-1282.
Power ultrasound in the classroom: efficient methodology for the fast degradation of organic matter in urine
Bertolo-Pardo, E., Capelo, J., Oliveira, E., Santos, H., Fernández-Lodeiro, J. and Lodeiro, C. 2009. Power ultrasound in the classroom: efficient methodology for the fast degradation of organic matter in urine. Electronic Journal of Environmental, Agricultural and Food Chemistry. 8 (11), pp. 1227-1239.
A new family of NxOy pyridine-containing macrocycles: synthesis and characterization of their Y(III), Ln(III), Zn(II), and Cd(II) coordination compounds
Lodeiro, C., Bastida, R., Bertolo-Pardo, E. and Rodriguez, A. 2004. A new family of NxOy pyridine-containing macrocycles: synthesis and characterization of their Y(III), Ln(III), Zn(II), and Cd(II) coordination compounds. Canadian Journal of Chemistry. 82 (3), pp. 437-447. https://doi.org/10.1139/v03-214
Synthesis and spectroscopic characterization of di-nuclear calcium complexes with oxa-aza macrocyclic ligands
Lodeiro, C., Bertolo-Pardo, E., Capelo, J. and Bastida, R. 2004. Synthesis and spectroscopic characterization of di-nuclear calcium complexes with oxa-aza macrocyclic ligands. Zeitschrift für anorganische und allgemeine Chemie. 630 (6), pp. 914-920. https://doi.org/10.1002/zaac.200400039
Manganese(II), cobalt(II), and nickel(II) perchlorate complexes containing N, O Donor macrocyclic ligands
Lodeiro, C., Capelo, J., Bertolo-Pardo, E. and Bastida, R. 2004. Manganese(II), cobalt(II), and nickel(II) perchlorate complexes containing N, O Donor macrocyclic ligands. Zeitschrift für anorganische und allgemeine Chemie. 630 (7), pp. 1110-1115. https://doi.org/10.1002/zaac.200400087
Metal complexes with four macrocyclic ligands derived from 2,6-bis(2-formylphenoxymethyl)pyridine and 1,7-bis(2′-formylphenyl)-1,4,7-trioxaheptane
Lodeiro, C., Bastida, R., Bertolo-Pardo, E., Macias, A. and Rodriguez, A. 2003. Metal complexes with four macrocyclic ligands derived from 2,6-bis(2-formylphenoxymethyl)pyridine and 1,7-bis(2′-formylphenyl)-1,4,7-trioxaheptane. Inorganica Chimica Acta. 343, pp. 133-140. https://doi.org/10.1016/S0020-1693(02)01172-6
Synthesis and characterisation of four novel NxOy-Schiff-base macrocyclic ligands and their metal complexes
Lodeiro, C., Bastida, R., Bertolo-Pardo, E., Macias, A. and Rodriguez, A. 2003. Synthesis and characterisation of four novel NxOy-Schiff-base macrocyclic ligands and their metal complexes. Transition Metal Chemistry. 28 (4), pp. 388-394. https://doi.org/10.1023/A:1023672629805
Lanthanide(III) complexes with pyridine head macrocyclic ligands
Bertolo-Pardo, E., Bastida, R., Fenton, D., Lodeiro, C., Macias, A. and Rodriguez, A. 2003. Lanthanide(III) complexes with pyridine head macrocyclic ligands. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 45 (1-2), pp. 155-160. https://doi.org/10.1023/A:1023021125195
Coordination chemistry of copper(II) with oxaaza macrocyclic ligands: crystal structure of a dinuclear tetramer copper(II) complex
Lodeiro, C., Bastida, R., Bertolo-Pardo, E., Macias, A. and Rodriguez, A. 2003. Coordination chemistry of copper(II) with oxaaza macrocyclic ligands: crystal structure of a dinuclear tetramer copper(II) complex. Polyhedron. 22 (13), pp. 1701-1710. https://doi.org/10.1016/S0277-5387(03)00332-2
Simulating environmental surveys using custom developed software
Bertolo-Pardo, E. and Clay, S. 2006. Simulating environmental surveys using custom developed software. Planet. 17, pp. 42-43.
Research informed teaching: enhancing the teaching-research nexus in science disciplines
Bertolo-Pardo, E. 2009. Research informed teaching: enhancing the teaching-research nexus in science disciplines. in: Lazinica, A. and Calafate, C. (ed.) Technology, Education and Development In-Tech. pp. 367-376
Engaging bioscience students with chemistry using VLEs
Bertolo-Pardo, E. 2008. Engaging bioscience students with chemistry using VLEs. Centre for Bioscience Bulletin. 23, p. 11.
Synthesis, characterization, and fluorescence behaviour of four novel macrocyclic emissive ligands containing a flexible 8-hydroxyquinoline unit
Nuñez, C., Bastida, R., Macias, A., Bertolo-Pardo, E., Fernandes, L., Capelo, J. and Lodeiro, C. 2009. Synthesis, characterization, and fluorescence behaviour of four novel macrocyclic emissive ligands containing a flexible 8-hydroxyquinoline unit. Tetrahedron. 65 (31), pp. 6179-6188. https://doi.org/10.1016/j.tet.2009.05.046
Exploiting anionic and cationic interactions with a new emissive imine-based β-naphthol molecular probe
Fernandes, L., Boucher, M., Fernández-Lodeiro, J., Oliveira, E., Nuñez, C., Santos, H., Capelo, J., Faza, O., Bertolo-Pardo, E. and Lodeiro, C. 2009. Exploiting anionic and cationic interactions with a new emissive imine-based β-naphthol molecular probe. Inorganic Chemistry Communications. 12 (9), pp. 905-912. https://doi.org/10.1016/j.inoche.2009.07.011
Web 2.0: Unlearned lessons from previous virtual learning environments
Bertolo-Pardo, E. 2008. Web 2.0: Unlearned lessons from previous virtual learning environments. Bioscience Education e-Journal. 11. https://doi.org/10.3108/beej.11.7
Metal ion interaction with a novel anthracene pendant-armed fluorescent molecular probe: synthesis, characterization, and fluorescence studies
Oliveira, E., Vicente, M., Valencia, L., Macias, A., Bertolo-Pardo, E., Bastida, R. and Lodeiro, C. 2007. Metal ion interaction with a novel anthracene pendant-armed fluorescent molecular probe: synthesis, characterization, and fluorescence studies. Inorganica Chimica Acta. 360 (8), pp. 2734-2743. https://doi.org/10.1016/j.ica.2007.01.024
Sensing metal ions with two new azomethine–thiophene pincer ligands (NSN): fluorescence and MALDI-TOF-MS applications
Pedras, B., Santos, H., Fernandes, L., Covelo, B., Tamayo, A., Bertolo-Pardo, E., Capelo, J., Aviles, T. and Lodeiro, C. 2007. Sensing metal ions with two new azomethine–thiophene pincer ligands (NSN): fluorescence and MALDI-TOF-MS applications. Inorganic Chemistry Communications. 10 (8), pp. 925-929. https://doi.org/10.1016/j.inoche.2007.05.001
N,N'-{1,3-Phenylenebis[methyleneoxy-2,1-phenylene(Z)methylylidene]}bis[1-(1-naphthyl)methanamine]
George, L., Bertolo-Pardo, E. and Lodeiro, C. 2010. N,N'-{1,3-Phenylenebis[methyleneoxy-2,1-phenylene(Z)methylylidene]}bis[1-(1-naphthyl)methanamine]. Molbank. 2010 (4), p. M702. https://doi.org/10.3390/M702
Neuregulins in the nucleus
McClelland, C. and Gullick, W. 2009. Neuregulins in the nucleus. in: Giordano, A. and Normanno, N. (ed.) Breast Cancer In the Post-Genomic Era Springer. pp. 79-86
Proteomic identification of secreted proteins as surrogate markers for signal transduction inhibitor activity
McClelland, C. and Gullick, W. 2007. Proteomic identification of secreted proteins as surrogate markers for signal transduction inhibitor activity. British Journal of Cancer. 96 (2), pp. 284-289. https://doi.org/10.1038/sj.bjc.6603544
Oxygen diffusion in SrCe 0.95Yb 0.05O 3-d
Bertolo-Pardo, E., Kilner, J. and Sahibzada, M. 2004. Oxygen diffusion in SrCe 0.95Yb 0.05O 3-d. Journal of Solid State Electrochemistry. 8 (9), pp. 585-591. https://doi.org/10.1007/s10008-003-0487-4
99mTc-SnF2 colloid “LLK”: particle size, morphology, and leukocyte labelling behaviour
McClelland, C., Onuegbulem, E., Carter, N., Leahy, M., O'Doherty, M., Pooley, F., O'Doherty, T., Newsam, R., Ensing, G. and Blower, P. 2003. 99mTc-SnF2 colloid “LLK”: particle size, morphology, and leukocyte labelling behaviour. Nuclear Medicine Communications. 24 (2), pp. 191-202. https://doi.org/10.1097/01.mnm.0000057333.59072.1c
Identification of surrogate markers for determining drug activity using proteomics
McClelland, C. and Gullick, W. 2003. Identification of surrogate markers for determining drug activity using proteomics. Biochemical Society Transactions. 31 (6), pp. 1488-1490. https://doi.org/10.1042/bst0311488