Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring.
Journal article
Ling Li MB, Bin Wu MM, Jiaoxuan Dong MM, Songbin He MM, Jie Xu MM, Gary Tse PhD, Fangyu Dai MM and Haipeng Liu PhD 2024. Hemodynamic changes in progressive cerebral infarction: An observational study based on blood pressure monitoring. Journal of Clinical Hypertension. 26 (2), pp. 122-133.
Authors | Ling Li MB, Bin Wu MM, Jiaoxuan Dong MM, Songbin He MM, Jie Xu MM, Gary Tse PhD, Fangyu Dai MM and Haipeng Liu PhD |
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Abstract | Progressive cerebral infarction (PCI) is a common complication in patients with ischemic stroke that leads to poor prognosis. Blood pressure (BP) can indicate post-stroke hemodynamic changes which play a key role in the development of PCI. The authors aim to investigate the association between BP-derived hemodynamic parameters and PCI. Clinical data and BP recordings were collected from 80 patients with cerebral infarction, including 40 patients with PCI and 40 patients with non-progressive cerebral infarction (NPCI). Hemodynamic parameters were calculated from the BP recordings of the first 7 days after admission, including systolic and diastolic BP, mean arterial pressure, and pulse pressure (PP), with the mean values of each group calculated and compared between daytime and nighttime, and between different days. Hemodynamic parameters and circadian BP rhythm patterns were compared between PCI and NPCI groups using t-test or non-parametric equivalent for continuous variables, Chi-squared test or Fisher's exact test for categorical variables, Cox proportional hazards regression analysis and binary logistic regression analysis for potential risk factors. In PCI and NPCI groups, significant decrease of daytime systolic BP appeared on the second and sixth days, respectively. Systolic BP and fibrinogen at admission, daytime systolic BP of the first day, nighttime systolic BP of the third day, PP, and the ratio of abnormal BP circadian rhythms were all higher in the PCI group. PCI and NPCI groups were significantly different in BP circadian rhythm pattern. PCI is associated with higher systolic BP, PP and more abnormal circadian rhythms of BP. |
Keywords | Blood pressure; Hemodynamic parameters; Progressive cerebral infarction (PCI); Stroke |
Year | 2024 |
Journal | Journal of Clinical Hypertension |
Journal citation | 26 (2), pp. 122-133 |
Publisher | Wiley |
ISSN | 1524-6175 |
1751-7176 | |
Official URL | https://onlinelibrary.wiley.com/doi/10.1111/jch.14759 |
Publication dates | |
Online | 08 Jan 2024 |
Publication process dates | |
Accepted | 08 Dec 2023 |
Deposited | 21 Feb 2024 |
Publisher's version | License File Access Level Open |
Output status | Published |
https://repository.canterbury.ac.uk/item/97273/hemodynamic-changes-in-progressive-cerebral-infarction-an-observational-study-based-on-blood-pressure-monitoring
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Publisher's version
J of Clinical Hypertension - 2024 - Li - Hemodynamic changes in progressive cerebral infarction An observational study.pdf | ||
License: CC BY-NC 4.0 | ||
File access level: Open |
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