Biased interpretation in paranoia and its modification

Journal article

George Savulich, Annabel Edwards, Sara Assadi, Husniye Guven, Emily Leathers-Smith, Sukhi Shergill and Jenny Yiend 2020. Biased interpretation in paranoia and its modification. Journal of Behavior Therapy and Experimental Psychiatry. 69, p. 101575. https://doi.org/10.1016/j.jbtep.2020.101575
AuthorsGeorge Savulich, Annabel Edwards, Sara Assadi, Husniye Guven, Emily Leathers-Smith, Sukhi Shergill and Jenny Yiend
Abstract

Background and objectives
Cognitive models of psychosis implicate interpretation biases as one of the mechanisms involved in the formation and maintenance of symptoms. First we measured the strength of association between interpretation biases and psychosis-relevant traits. Next we manipulated these biases and quantified the effects of doing so on psychosis-relevant outcomes.

Methods
Experiment 1 used two measures of interpretation bias in a healthy sample (n = 70). Experiment 2 used a novel cognitive bias modification procedure (CMB-pa) in individuals with moderate trait paranoia (n = 60).

Results
Experiment 1 revealed that over a third of the variance in interpretation bias could be explained by the combined effect of trait measures of paranoia/psychosis. In Experiment 2, CBM-pa produced training-congruent changes in the interpretation of new ambiguous information and influenced the interpretation, attribution and distress associated with a real-life social event.

Limitations
The potentially confounding effects of elevated anxiety and depression on interpretation bias and the restricted range of outcome measures to assess the wider effects of CBM-pa.

Conclusions
These studies are consistent with interpretation biases contributing to the maintenance of paranoia. CBM-pa could next be adapted and evaluated to test its efficacy as a therapeutic intervention.

KeywordsParanoia; Interpretation bias; Cognitive bias modification; Information processing
Year2020
JournalJournal of Behavior Therapy and Experimental Psychiatry
Journal citation69, p. 101575
PublisherElsevier
ISSN0005-7916
1873-7943
Digital Object Identifier (DOI)https://doi.org/10.1016/j.jbtep.2020.101575
Official URLhttps://www.sciencedirect.com/science/article/pii/S0005791619300904
Publication dates
Online04 May 2020
Publication process dates
Accepted27 Apr 2020
Deposited19 Jun 2023
Output statusPublished
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