Autologous collagen-induced chondrogenesis: From bench to clinical development

Journal article


Chun, You Seung, Kim, Seon Ae, Kim, Yun Hwan, Lee, Joong Hoon, Shetty, Asode Ananthram and Kim, S. 2023. Autologous collagen-induced chondrogenesis: From bench to clinical development. Medicina (Kaunas, Lithuania). 59 (3), p. 530. https://doi.org/10.3390/medicina59030530
AuthorsChun, You Seung, Kim, Seon Ae, Kim, Yun Hwan, Lee, Joong Hoon, Shetty, Asode Ananthram and Kim, S.
AbstractMicrofracture is a common technique that uses bone marrow components to stimulate cartilage regeneration. However, the clinical results of microfracture range from poor to good. To enhance cartilage healing, several reinforcing techniques have been developed, including porcine-derived collagen scaffold, hyaluronic acid, and chitosan. Autologous collagen-induced chondrogenesis (ACIC) is a single-step surgical technique for cartilage regeneration that combines gel-type atelocollagen scaffolding with microfracture. Even though ACIC is a relatively new technique, literature show excellent clinical results. In addition, all procedures of ACIC are performed arthroscopically, which is increasing in preference among surgeons and patients. The ACIC technique also is called the Shetty–Kim technique because it was developed from the works of A.A. Shetty and S.J. Kim. This is an up-to-date review of the history of ACIC.
Year2023
JournalMedicina (Kaunas, Lithuania)
Journal citation59 (3), p. 530
PublisherMDPI AG
ISSN1648-9144
Digital Object Identifier (DOI)https://doi.org/10.3390/medicina59030530
Official URLhttps://www.mdpi.com/1648-9144/59/3/530
Publication dates
Online08 Mar 2023
Publication process dates
Accepted07 Mar 2023
Deposited20 Mar 2023
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Output statusPublished
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