Editorial: Eating disorders and emotion regulation, looking at the spectrum from overcontrolling to dysregulation.

Journal article


Meneguzzo, Paolo, Oldershaw, Anna Victoria, Monaco, Francesco and Giel, Katrin 2022. Editorial: Eating disorders and emotion regulation, looking at the spectrum from overcontrolling to dysregulation. Frontiers in Psychiatry. 13, p. 976500. https://doi.org/10.3389/fpsyt.2022.976500
AuthorsMeneguzzo, Paolo, Oldershaw, Anna Victoria, Monaco, Francesco and Giel, Katrin
Abstract

Background and aims
Advancing age is the most important risk factor of atrial fibrillation (AF). The shortening of telomere length is a biomarker of biologic aging. There is an increasing body of evidence that leucocyte telomere length (LTL) is associated with the risk of AF development. However, the results in these studies were controversial. The current systematic review and meta-analysis was conducted to examine the role of LTL in predicting the incidence of AF.

Methods and results
Observational studies reporting the association between LTL and the risk of AF were retrieved through 25th June, 2022 from PubMed and Embase. A total of twelve studies including 18,293 patients were included in the present analysis. Leucocyte telomere shortening was found to be an independent predictor of AF as a continuous variable in both univariate [OR:2.14; 95%CI(1.48,3.10); P < 0.0001] and multivariate analyses [OR:1.41;95%CI(1.11,1.79); P = 0.005], as well as categorical variable in multivariate analysis [OR:1.53; 95%CI(1.04,2.27); P = 0.03]. Furthermore, leucocyte telomere shortening was significantly associated with recurrent AF [OR:4.32;95%CI(2.42,7.69); P < 0.00001] but not new-onset AF [OR:1.14; 95%CI(0.90,1.45); P = 0.29]. Leucocyte telomere shortening was also associated with an increased risk of persistent AF [OR:14.73;95%CI (3.16,68.67); P = 0.0006] and paroxysmal AF [OR:2.74;95%CI(1.45,5.18); P = 0.002]. Besides, LTL was an independent predictor for progression from paroxysmal AF to persistent AF [OR:3.2;95%CI(1.66,6.18); P = 0.0005]. Differences between males [OR:1.99; 95%CI(1.29,3.06); P = 0.002] and females [OR:0.86; 95%CI (0.29,2.56);P = 0.79] were observed.

Conclusions
Leucocyte telomere shortening predicts the risk of AF, especially recurrent AF. The predictive value is more prominent in males than in females. Shortening in LTL can predict the progression from paroxysmal to persistent AF.

KeywordsEating disorders; Overcontrol; Emotional spectrum; Emotion regulation; Dysregulation
Year2022
JournalFrontiers in Psychiatry
Journal citation13, p. 976500
PublisherFrontiers
ISSN1664-0640
Digital Object Identifier (DOI)https://doi.org/10.3389/fpsyt.2022.976500
Official URLhttps://www.frontiersin.org/articles/10.3389/fpsyt.2022.976500/full
Publication dates
Online18 Jul 2022
Publication process dates
Deposited03 Aug 2022
Accepted04 Jul 2022
Publisher's version
License
Output statusPublished
Licensehttp://creativecommons.org/licenses/by/4.0/
Permalink -

https://repository.canterbury.ac.uk/item/91z13/editorial-eating-disorders-and-emotion-regulation-looking-at-the-spectrum-from-overcontrolling-to-dysregulation

Download files


Publisher's version
fpsyt-13-976500.pdf
License: CC BY 4.0

  • 28
    total views
  • 5
    total downloads
  • 1
    views this month
  • 3
    downloads this month

Export as

Related outputs

Seeing through the façade of Anorexia: A grounded theory of emotional change processes associated with recovery from Anorexia Nervosa
Drinkwater, Danielle, Holttum, Sue, Lavender, Tony, Startup, Helen and Oldershaw, Anna 2022. Seeing through the façade of Anorexia: A grounded theory of emotional change processes associated with recovery from Anorexia Nervosa. Frontiers in Psychiatry. 13, p. 868586. https://doi.org/10.3389/fpsyt.2022.868586