Consensus evidence-based recommendations for treat-to-target management of immunoglobulin A vasculitis
Journal article
Abu-Zaid, M., Salah S., Lotfy H., El Gaafary, M., Abdulhady, H., Tabra, S., Salah, H., Farag, Y., Eissa, M., Maher, S., Radwan, A., El-Shanawany, A., Medhat, B., El Mikkawy, D., Mosa D., El Deriny, G., Mortada M., Osman, N., Fouad, N., Elkaraly, N., Mohamed, S., Hassan, W., Amer, Y., Nasef, S. and El Miedany, Y. 2021. Consensus evidence-based recommendations for treat-to-target management of immunoglobulin A vasculitis. Therapeutic Advances in Musculoskeletal Disease. https://doi.org/10.1177/1759720X211059610
Authors | Abu-Zaid, M., Salah S., Lotfy H., El Gaafary, M., Abdulhady, H., Tabra, S., Salah, H., Farag, Y., Eissa, M., Maher, S., Radwan, A., El-Shanawany, A., Medhat, B., El Mikkawy, D., Mosa D., El Deriny, G., Mortada M., Osman, N., Fouad, N., Elkaraly, N., Mohamed, S., Hassan, W., Amer, Y., Nasef, S. and El Miedany, Y. |
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Abstract | IgA vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, is the most common cause of systemic vasculitis in childhood. Given its potential life-threatening systemic The preliminary scientific committee identified a total of 16 key clinical questions according to the patient, intervention, comparison, and outcomes (PICO) approach. An evidence-based, systematic, literature review was conducted to compile evidence for the IgAV management. The core leadership team identified researchers and clinicians with expertise in IgAV management in Egypt upon which experts were gathered from different governorates and health centers across Egypt. Delphi process was implemented (two rounds) to reach a consensus. An online questionnaire was sent to expert panel (n = 26) who participated in the two rounds. After completing round 2, a total of 20 recommendation items, categorized into two sections were Consensus was reached (i.e. ⩾75% of respondents strongly agreed or agreed) on the wording of all the 20 clinical standards identified by the scientific committee. Algorithms for the diagnosis and management have been suggested. This was an expert, consensus recommendations for the diagnosis and treatment of IgAV and IgA vasculitic nephritis, based on best available evidence and expert opinion. The guideline presented a strategy of care with a pathway to achieve a state of remission as early as possible. |
Keywords | Egypt; Egyptian guidelines IgA vasculitis; Guidelines; Henoch-Schönlein purpura; IgA vasculitis; Vasculitis algorithm |
Year | 2021 |
Journal | Therapeutic Advances in Musculoskeletal Disease |
Publisher | SAGE |
ISSN | 1759-720X |
1759-7218 | |
Digital Object Identifier (DOI) | https://doi.org/10.1177/1759720X211059610 |
Official URL | https://journals.sagepub.com/doi/10.1177/1759720X211059610 |
Publication dates | |
Online | 09 Dec 2021 |
Publication process dates | |
Accepted | 26 Oct 2021 |
Deposited | 16 Jun 2022 |
Publisher's version | License |
Output status | Published |
https://repository.canterbury.ac.uk/item/913x4/consensus-evidence-based-recommendations-for-treat-to-target-management-of-immunoglobulin-a-vasculitis
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