Consensus evidence-based recommendations for treat-to-target management of immunoglobulin A vasculitis

Journal article


Abu-Zaid, M., Salah S., Lotfy H., El Gaafary, M., Abdulhady, H., Tabra, S., Salah, H., Farag, Y., Eissa, M., Maher, S., Radwan, A., El-Shanawany, A., Medhat, B., El Mikkawy, D., Mosa D., El Deriny, G., Mortada M., Osman, N., Fouad, N., Elkaraly, N., Mohamed, S., Hassan, W., Amer, Y., Nasef, S. and El Miedany, Y. 2021. Consensus evidence-based recommendations for treat-to-target management of immunoglobulin A vasculitis. Therapeutic Advances in Musculoskeletal Disease. https://doi.org/10.1177/1759720X211059610
AuthorsAbu-Zaid, M., Salah S., Lotfy H., El Gaafary, M., Abdulhady, H., Tabra, S., Salah, H., Farag, Y., Eissa, M., Maher, S., Radwan, A., El-Shanawany, A., Medhat, B., El Mikkawy, D., Mosa D., El Deriny, G., Mortada M., Osman, N., Fouad, N., Elkaraly, N., Mohamed, S., Hassan, W., Amer, Y., Nasef, S. and El Miedany, Y.
Abstract

IgA vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, is the most common cause of systemic vasculitis in childhood. Given its potential life-threatening systemic
complications, early and accurate diagnosis as well as management of IgAV represent a major challenge for health care professionals. This study was carried out to attain an evidence-based expert consensus on a treat-to-target management approach for IgAV using Delphi technique.

The preliminary scientific committee identified a total of 16 key clinical questions according to the patient, intervention, comparison, and outcomes (PICO) approach. An evidence-based, systematic, literature review was conducted to compile evidence for the IgAV management.

The core leadership team identified researchers and clinicians with expertise in IgAV management in Egypt upon which experts were gathered from different governorates and health centers across Egypt. Delphi process was implemented (two rounds) to reach a consensus. An online questionnaire was sent to expert panel (n = 26) who participated in the two rounds. After completing round 2, a total of 20 recommendation items, categorized into two sections were
obtained. Agreement with the recommendations (rank 7–9) ranged from 91.7–100%.

Consensus was reached (i.e. ⩾75% of respondents strongly agreed or agreed) on the wording of all the 20 clinical standards identified by the scientific committee. Algorithms for the diagnosis and management have been suggested. This was an expert, consensus recommendations for the diagnosis and treatment of IgAV and IgA vasculitic nephritis, based on best available evidence and expert opinion. The guideline presented a strategy of care with a pathway to achieve a state of remission as early as possible.

KeywordsEgypt; Egyptian guidelines IgA vasculitis; Guidelines; Henoch-Schönlein purpura; IgA vasculitis; Vasculitis algorithm
Year2021
JournalTherapeutic Advances in Musculoskeletal Disease
PublisherSAGE
ISSN1759-720X
1759-7218
Digital Object Identifier (DOI)https://doi.org/10.1177/1759720X211059610
Official URLhttps://journals.sagepub.com/doi/10.1177/1759720X211059610
Publication dates
Online09 Dec 2021
Publication process dates
Accepted26 Oct 2021
Deposited16 Jun 2022
Publisher's version
License
Output statusPublished
Permalink -

https://repository.canterbury.ac.uk/item/913x4/consensus-evidence-based-recommendations-for-treat-to-target-management-of-immunoglobulin-a-vasculitis

Download files


Publisher's version
1 HSP pub.pdf
License: CC BY-NC 4.0

  • 154
    total views
  • 28
    total downloads
  • 6
    views this month
  • 2
    downloads this month

Export as

Related outputs

Defining criteria for disease activity states in systemic juvenile idiopathic arthritis based on the systemic Juvenile Arthritis Disease Activity Score
Rosina, Silvia, Rebollo‐Gimenez, Ana I., Tarantola, Letizia, Pistorio, Angela, Vyzhga, Y., El Miedany, Yasser, Lotfy, Hala M., Abu‐Shady, Hend, Eissa, M., Osman, Naglaa S., Hassan, Waleed, Mahgoub, Marwa Y., Fouad, Nermeen A., Mosa, D., Adel, Yasmin, Mohamed, Sheren E. M., Radwan, Ahmed R., Abu-Zaid, M., Tabra, Samar A. A., Shalaby, Radwa H., Nasef, S., Khubchandani, Raju, Khan, A., Maldar, Naziya P., Ozen, S., Bayindir, Yagmur, Alsuweiti, Motasem, Alzyoud, Raed, Almaaitah, Hiba, Vilaiyuk, Soamarat, Lerkvaleekul, Butsabong, Alexeeva, Ekaterina, Dvoryakovskaya, Tatyana, Kriulin, Ivan, Bracaglia, C., Pardeo, M., De Benedetti, F., Licciardi, F., Montin, Davide, Robasto, Francesca, Minoia, F., Filocamo, Giovanni, Rossano, Martina, Simonini, Gabriele, Marrani, Edoardo, Abu‐Rumeleih, S., Kostik, M., Belozerov, Konstantin E., Pal, P., Bathia, Jigna N., Katsicas, María M., Villarreal, Giselle, Marino, Achille, Costi, Stefania, Sztajnbok, Flavio, Silva, Rodrigo M., Maggio, Maria C., El‐Ghoneimy, Dalia H., El Owaidy, R., Civino, Adele, Diomeda, Federico, Al‐Mayouf, Sulaiman M., Al‐Sofyani, Fuad, Dāvidsone, Zane, Patrone, Elisa, Saad‐Magalhães, Claudia, Consolaro, A. and Ravelli, A. 2024. Defining criteria for disease activity states in systemic juvenile idiopathic arthritis based on the systemic Juvenile Arthritis Disease Activity Score. Arthritis & Rheumatology. https://doi.org/10.1002/art.42865
Consensus on the definitions and descriptions of the domains of the OMERACT Core Outcome Set for shared decision making interventions in rheumatology trials
Décary, Simon, de Wit, Maarten, Naye, Florian, Barton, Jennifer L., Fraenkel, Liana, Li, Linda C., Brooks, Peter, Stacey, Dawn, Maxwell, Lara J., Campbell, Willemina, Hofstetter, Cathie, Voshaar, Marieke, Meara, Alexa, Christensen, Robin, Boonen, Annelies, Suarez-Almazor, Maria E., Meade, Tanya, March, Lyn, Jull, Janet Elizabeth, Alten, Rieke, Morgan, Esi M., Hazlewood, Glen, Barber, Claire, Guillemin, Francis, El-Miedany, Yasser, Mittoo, Shikha, Robertson, Tiffany Westrich, Bartlett, Susan J., Singh, Jasvinder A., Mannion, Melissa, Nasef, Samah Ismail, Boel, Anne, Adebajo, Adewale, Arnaud, Laurent, Gill, Tiffany K., Moholt, Ellen, Burt, Jennifer, Jayatilleke, Arundathi, Hmamouchi, Ihsane, Berthelsen, Dorthe B, Blanco, Francisco J., Mather, Kate, Maharaj, Ajesh, Sharma, Saurab, Caso, Francesco, Beaton, Dorcas, Shea, Beverly, Fong, Christopher, Fernandez, Anthony P., Mackie, Sarah, Nikiphorou, Elena, Jones, Allyson, Greer-Smith, Regina, Sloan, Victor S., Akpabio, Akpabio, Strand, Vibeke, Lee, Rebecca R., Umaefulam, Valerie, Monti, Sara, Abaza, Nouran, Schultz, Grayson, Stones, Simon, Gossec, Laure, Nielsen, Sabrina Mai, Cavallo, Sabrina, Srinivasalu, Hemalatha, Constien, Deb, Evans, Vicki, Tugwell, Peter and Toupin-April, K. 2024. Consensus on the definitions and descriptions of the domains of the OMERACT Core Outcome Set for shared decision making interventions in rheumatology trials. Seminars in Arthritis and Rheumatism. 65, p. 152381. https://doi.org/10.1016/j.semarthrit.2024.152381
Core outcome measurement set for shared decision making in rheumatic and musculoskeletal conditions: A scoping review to identify candidate instruments
Naye, Florian, Toupin-April, Karine, de Wit, Maarten, LeBlanc, Annie, Dubois, Olivia, Boonen, Annelies, Barton, Jennifer L., Fraenkel, Liana, Li, Linda C., Stacey, Dawn, March, Lyn, Barber, Claire E.H., Hazlewood, Glen Stewart, Guillemin, Francis, Bartlett, Susan J., Berthelsen, Dorthe B., Mather, Kate, Arnaud, Laurent, Akpabio, Akpabio, Adebajo, Adewale, Schultz, Grayson, Sloan, Victor S., Gill, Tiffany K., Sharma, Saurab, Scholte-Voshaar, Marieke, Caso, Francesco, Nikiphorou, Elena, Nasef, Samah Ismail, Campbell, Willemina, Meara, Alexa, Christensen, Robin, Suarez-Almazor, Maria E., Jull, Janet Elizabeth, Alten, Rieke, Morgan, Esi M., El-Miedany, Yasser, Singh, Jasvinder A., Burt, Jennifer, Jayatilleke, Arundathi, Hmamouchi, Ihsane, Blanco, Francisco J., Fernandez, Anthony P., Mackie, Sarah, Jones, Allyson, Strand, Vibeke, Monti, Sara, Stones, Simon R., Lee, Rebecca R., Nielsen, Sabrina Mai, Evans, Vicki, Srinivasalu, Hemalatha, Gérard, Thomas, Demers, Juliette LeBlanc, Bouchard, Roxanne, Stefan, Théo, Dugas, Michèle, Bergeron, Frédéric, Beaton, Dorcas, Maxwell, Lara J., Tugwell, Peter and Décary, Simon 2023. Core outcome measurement set for shared decision making in rheumatic and musculoskeletal conditions: A scoping review to identify candidate instruments. Seminars in Arthritis and Rheumatism. 65, p. 152344. https://doi.org/10.1016/j.semarthrit.2023.152344
Beyond the symptoms: Personalizing giant cell arteritis care through multidimensional patient reported outcome measure
El Miedany, Y., El Gaafary, M, Toth, M, Palmer, D., Ali, Ayman, Bahlas, S., Mahran, S., Hassan, W., Abu-Zaid, M H, Saber, S. and Elwakil, W. 2023. Beyond the symptoms: Personalizing giant cell arteritis care through multidimensional patient reported outcome measure. Seminars in Arthritis and Rheumatism. 63, p. 152285. https://doi.org/10.1016/j.semarthrit.2023.152285
Prevalence of glucocorticoid-induced osteoporosis among rheumatology patients in Africa: a systematic review and meta-analysis.
Hmamouchi, I., Paruk, Farhanah, Tabra, Samar, Maatallah, Kaouther, Bouziane, Amal, Abouqal, Redouane, El Maidany, Yasser, El Maghraoui, Abdellah and Kalla, Asgar Ali 2023. Prevalence of glucocorticoid-induced osteoporosis among rheumatology patients in Africa: a systematic review and meta-analysis. Archives of Osteoporosis. 18 (1), p. 59. https://doi.org/10.1007/s11657-023-01246-6
Consensus evidence-based clinical practice recommendations for the diagnosis and treat-to-target management of osteoporosis in chronic kidney disease stages G4-G5D and post-transplantation: An initiative of Egyptian Academy of Bone Health
El Miedany, Yasser, Gadallah, Naglaa Ali, Sarhan, Eman, Toth, Mathias, Hasab El Naby, Mona Mansour, Elwy, Mohamed, Ganeb, Sahar, El Gaafary, Maha, Mortada, Mohamed, Nasef, Samah Ismail, Mohannad, Nevine, Mahran, Safaa Ali, Abu-Zaid, Mohammed Hassan, Eissa, Mervat, Hassan, Waleed, Medhat, Basma M, Ghaleb, Rasha, Tabra, Samar Abdelhamed, Saber, Heba Gamal, Ibrahim, Rehab Ali, Saber, Sally and Galal, Salwa 2022. Consensus evidence-based clinical practice recommendations for the diagnosis and treat-to-target management of osteoporosis in chronic kidney disease stages G4-G5D and post-transplantation: An initiative of Egyptian Academy of Bone Health. Kidney Diseases. 8 (5), pp. 392-407. https://doi.org/10.1159/000526492
001 Egyptian consensus-based recommendations for the diagnosis and targeted management of Kawasaki disease. An initiative by the Egyptian College of Pediatric Rheumatology
El Miedany, Y, Lotfy, H, Salah, S, Abu-Zaid, M. H, Mohamed, S. S, Esam Maher, S, El Gaafary, M, Abdulhady, H, Hassan, W. A, Mortada, M, Amer, Y, Osman, N. S, Medhat, B. M, Farag, Y, Eissa, M, Radwan, A, Nasef, S. I, Elkaraly, N. E, El-Shanawany, Amira T, El Mikkawy, D, Mosa, D. M, El Deriny, G, Fouad, N. A and Tabra, S. A 2022. 001 Egyptian consensus-based recommendations for the diagnosis and targeted management of Kawasaki disease. An initiative by the Egyptian College of Pediatric Rheumatology. Rheumatology. 61 (Supplement_2). https://doi.org/10.1093/rheumatology/keac495.001
43 Egyptian evidence-based consensus recommendations for diagnosis and targeted management of childhood-onset systemic lupus erythematosus. An initiative by the Egyptian College of Pediatric Rheumatology
Lotfy, H, El Miedany, Y, Salah, S, Tabra, S. A, Salaby, R. A, Amer, Y, Adel, Y, Osman, N. S, Medhat, B. M, El Gaafary, M, Abdulhady, H, Hassan, W. A, Farag, Y, Eissa, M, Maher, S. Esam, Radwan, A, El-Shanawany, Amira T, El Mikkawy, D, Mosa, D. M, El Deriny, G, Mortada, M, Fouad, N. A, Nasef, S. I, Elkaraly, N. E, Mohamed, S. S and Abu-Zaid, M. H 2022. 43 Egyptian evidence-based consensus recommendations for diagnosis and targeted management of childhood-onset systemic lupus erythematosus. An initiative by the Egyptian College of Pediatric Rheumatology. Rheumatology. 61 (Supplement_2). https://doi.org/10.1093/rheumatology/keac496.039
Regenerative medicine : Challenges and opportunities
Plummer, S. and El Miedany, Y. 2022. Regenerative medicine : Challenges and opportunities. in: El Miedany, Y. (ed.) Musculoskeletal Ultrasound-Guided Regenerative Medicine Springer. pp. 539 -548
Rheumatology-led pregnancy clinic: patient-centred approach
El Miedany, Y. and Palmer, D. 2021. Rheumatology-led pregnancy clinic: patient-centred approach. Clinical Rheumatology. 40 (10), pp. 3875-3882. https://doi.org/10.1007/s10067-021-05690-y
Egyptian consensus on treat-to-target approach for osteoporosis: a clinical practice guideline from the Egyptian Academy of bone health and metabolic bone diseases
El Miedany, Y., Abu-Zaid, M., El Gaafary, M., El Naby, M., Fathi N., Saber H., Hassan, W., Eissa M., Mohannad N., Khaled H., Mortada M., Nasef S., Galal, S., Ghaleb R., Tabra S., Mohamed S., Medhat B., Aly H., Elolemy G., Fouad N., Ganeb S., Adel Y., Ibrahim M., Farouk O. and Gadallah N. 2021. Egyptian consensus on treat-to-target approach for osteoporosis: a clinical practice guideline from the Egyptian Academy of bone health and metabolic bone diseases. Egyptian Rheumatology and Rehabilitation. 48 (5). https://doi.org/10.1186/s43166-020-00056-9
Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases.
El Miedany, Y., Paruk, F., Kalla, A., Adebajo, A., El Gaafary, M., El Maghraoui, A., Ngandeu, M., Dey, D., Gadallah, Naglaa, Elwy, Mohamed, Moosajee, F., Abu-Zaid, M., Galal, S., Miladi, S., Hassan, W., Fadlelmola, Abubaker and Saber, S. 2021. Consensus evidence-based clinical practice guidelines for the diagnosis and treat-to-target management of osteoporosis in Africa: an initiative by the African Society of Bone Health and Metabolic Bone Diseases. Archives of Osteoporosis. 16 (1), p. 176. https://doi.org/10.1007/s11657-021-01035-z
Is there a potential dual effect of denosumab for treatment of osteoporosis and sarcopenia?
Miedany, Yasser El, Gaafary, Maha El, Toth, Mathias, Hegazi, Mohamed Osama, Aroussy, Nadia El, Hassan, Waleed, Almedany, Samah, Nasr, Annie, Bahlas, Sami, Galal, S. and Egyptian Academy of Bone Health, Metabolic Bone Diseases 2021. Is there a potential dual effect of denosumab for treatment of osteoporosis and sarcopenia? Clinical Rheumatology. https://doi.org/10.1007/s10067-021-05757-w
Endorsement of the OMERACT core domain set for shared decision making interventions in rheumatology trials: Results from a multi-stepped consensus-building approach.
Toupin-April, K., Décary, S., de Wit, M., Meara, A., Barton, J. L., Fraenkel, L., Li, L. C., Brooks, P., Shea, B., Stacey, D., Légaré, F., Lydiatt, A., Hofstetter, C., Proulx, L., Christensen, R., Voshaar, M., Suarez-Almazor, M. E, Boonen, A., Meade, T., March, L., Jull, J. E., Campbell, W., Alten, R., Morgan, E.M., Kelly, A., Kaufman, J., Hill, S., Maxwell, L. J., Guillemin, F., Beaton, D., El-Miedany, Y., Mittoo, S., Westrich Robertson, T., Bartlett, S. J., Singh, J. A., Mannion, M., Nasef, S. I., de Souza, S., Boel, A., Adebajo, A., Arnaud, L., Gill, T. K., Moholt, E., Burt, J., Jayatilleke, A., Hmamouchi, I., Carrott, D., Blanco, F. J., Mather, K., Maharaj, A., Sharma, S., Caso, F., Fong, C., Fernandez, A. P., Mackie, S., Nikiphorou, E., Jones, A., Greer-Smith, R., Sloan, V. S., Akpabio, A., Strand, V., Umaefulam, V., Monti, S., Melburn, C., Abaza, N., Schultz, K., Stones, S., Kiwalkar, S., Srinivasalu, H., Constien, D., King, L. K. and Tugwell, P. 2021. Endorsement of the OMERACT core domain set for shared decision making interventions in rheumatology trials: Results from a multi-stepped consensus-building approach. Seminars in Arthritis and Rheumatism. 51 (3). https://doi.org/10.1016/j.semarthrit.2021.03.017
Rheumatology-led pregnancy clinic: enhancing the care of women with rheumatic diseases during pregnancy
El Miedany, Y. and Palmer, D. 2020. Rheumatology-led pregnancy clinic: enhancing the care of women with rheumatic diseases during pregnancy. Clinical Rheumatology. 39 (12), pp. 3593-3601. https://doi.org/10.1007/s10067-020-05173-6
Widespread lytic lesions—A metastatic or vasculitic process?
Fahd Khan, Srinivasan Srirangan, Yasser El Miedany and Sanjeev Madaan 2016. Widespread lytic lesions—A metastatic or vasculitic process? International Journal of Surgery Case Reports. 18, pp. 18-20. https://doi.org/10.1016/j.ijscr.2015.11.023