Stochastic variation in DNA methylation modulates nucleosome occupancy and alternative splicing in Arabidopsis thaliana

Journal article

Jabre, Ibtissam, Chaudhary, S., Wilson, C., Staiger, D. and Syed, N. 2022. Stochastic variation in DNA methylation modulates nucleosome occupancy and alternative splicing in Arabidopsis thaliana. Plants. 11 (9), p. 1105. https://doi.org/10.3390/plants11091105
AuthorsJabre, Ibtissam, Chaudhary, S., Wilson, C., Staiger, D. and Syed, N.
AbstractPlants use complex gene regulatory mechanisms to overcome diverse environmental challenges. For instance, cold stress induces rapid and massive transcriptome changes via alternative splicing (AS) to confer cold tolerance in plants. In mammals, mounting evidence suggests chromatin structure can regulate co-transcriptional AS. Recent evidence also supports co-transcriptional regulation of AS in plants, but how dynamic changes in DNA methylation and the chromatin structure influence the AS process upon cold stress remains poorly understood. In this study, we used the DNA methylation inhibitor 5-Aza-2′-Deoxycytidine (5-aza-dC) to investigate the role of stochastic variations in DNA methylation and nucleosome occupancy in modulating cold-induced AS, in Arabidopsis thaliana (Arabidopsis). Our results demonstrate that 5-aza-dC derived stochastic hypomethylation modulates nucleosome occupancy and AS profiles of genes implicated in RNA metabolism, plant hormone signal transduction, and of cold-related genes in response to cold stress. We also demonstrate that cold-induced remodelling of DNA methylation regulates genes involved in amino acid metabolism. Collectively, we demonstrate that sudden changes in DNA methylation via drug treatment can influence nucleosome occupancy levels and modulate AS in a temperature-dependent manner to regulate plant metabolism and physiological stress adaptation.
KeywordsArabidopsis thaliana; Alternative splicing; Cold stress; Co-transcriptional Alternative Splicing; Stochastic Dna Methylation
Year2022
JournalPlants
Journal citation11 (9), p. 1105
PublisherMDPI AG
ISSN2223-7747
Digital Object Identifier (DOI)https://doi.org/10.3390/plants11091105
Official URLhttps://www.mdpi.com/2223-7747/11/9/1105
Publication dates
Print01 Apr 2022
Online19 Apr 2022
Publication process dates
Deposited20 Apr 2022
Accepted07 Apr 2022
Publisher's version
Output statusPublished
Additional information

Publications router.

Permalink -

https://repository.canterbury.ac.uk/item/90y6w/stochastic-variation-in-dna-methylation-modulates-nucleosome-occupancy-and-alternative-splicing-in-arabidopsis-thaliana

Download files

Publisher's version
plants-11-01105.pdf

  • 96
    total views
  • 46
    total downloads
  • 5
    views this month
  • 1
    downloads this month

Export as

Related outputs

Standard operating procedure for the operation of SEM-EDX for elemental analysis, with additional applications to biomass
Hernandez, E., Thomas, J.K., Kheirandish, K., Wilson, C. and Ortega, H. 2024. Standard operating procedure for the operation of SEM-EDX for elemental analysis, with additional applications to biomass. Canterbury Christ Church University. https://doi.org/10.5281/zenodo.13736742
Differential microRNA expression in the SH-SY5Y human cell model as potential biomarkers for Huntington’s disease
Belkozhayev, Ayaz, Niyazova, Raigul, Kamal, Mohammad Amjad, Ivashchenko, Anatoliy, Sharipov, Kamalidin and Wilson, C. 2024. Differential microRNA expression in the SH-SY5Y human cell model as potential biomarkers for Huntington’s disease. Frontiers in Cellular Neuroscience. 18, p. 1399742. https://doi.org/10.3389/fncel.2024.1399742
Novel transcriptional and DNA methylation abnormalities of SORT1 Gene in non-small cell lung cancer
Acha-Sagredo, Amelia, Wilson, C., Garcia Bediaga, Naiara, Kalirai, Helen, Davies, M., Coupland, S., Field, John K and Liloglou, T. 2024. Novel transcriptional and DNA methylation abnormalities of SORT1 Gene in non-small cell lung cancer. Cancers. 16 (11), p. 2154. https://doi.org/10.3390/cancers16112154
Editorial: Targeting nucleotide metabolism for enhancing antitumor immunity.
Wu, Jun, Rong, Yu, Li, Tian, Wilson, C., He, Yazhou, Chen, Danqian, Han, Jin and Zhang, Xingmei 2024. Editorial: Targeting nucleotide metabolism for enhancing antitumor immunity. Frontiers in Immunology. 15, p. 1412057. https://doi.org/10.3389/fimmu.2024.1412057
Investigating the effect of mesoporous silica nanoparticles as a drug delivery system for Withaferin A in the treatment of Lung Cancer
Holder, J., Wilson, C., Bertolo-Pardo, E., Byrne, L., Lodeiro, C., Oliveira, E. and Trim, C. 2024. Investigating the effect of mesoporous silica nanoparticles as a drug delivery system for Withaferin A in the treatment of Lung Cancer.
Investigating the effect of silica nanoparticles as a drug delivery system for Doxorubicin in the treatment of lung cancer
Holder, J., Wilson, C., Bertolo-Pardo, E., Byrne, L., Oliveira, E., Lodeiro, C. and Trim, C. 2024. Investigating the effect of silica nanoparticles as a drug delivery system for Doxorubicin in the treatment of lung cancer.
AI is a viable alternative to high throughput screening: a 318-target study
Wilson, C.M., Byrne, L., Al-Yozbaki, M. and The Atomwise AIMS Program 2024. AI is a viable alternative to high throughput screening: a 318-target study. Scientific Reports. https://doi.org/10.1038/s41598-024-54655-z
Mesenchymal stem cell-derived exosomes: Characteristics and applications in disease pathology and management.
Padinharayil, H., Varghese, J., Wilson, C. and George, A. 2024. Mesenchymal stem cell-derived exosomes: Characteristics and applications in disease pathology and management. Life Sciences. 342 (122542). https://doi.org/10.1016/j.lfs.2024.122542
Overview of hepatocellular carcinoma: from molecular aspects to future therapeutic options.
Panneerselvam, S., Wilson, Cornelia, Kumar, Prem, Abirami, Dinu, Pamarthi, Jayakrishna, Reddy, Mettu Srinivas and Varghese, Joy 2023. Overview of hepatocellular carcinoma: from molecular aspects to future therapeutic options. Cell Adhesion and Migration. 17 (1), pp. 1-21. https://doi.org/10.1080/19336918.2023.2258539
The use of nanoparticles for targeted drug delivery in non-small cell lung cancer.
Holder, Jessica E, Ferguson, C., Oliveira, Elisabete, Lodeiro, Carlos, Trim, Carol M, Byrne, Lee J, Bertolo, Emilia and Wilson, Cornelia M 2023. The use of nanoparticles for targeted drug delivery in non-small cell lung cancer. Frontiers in Oncology. 13, p. 1154318. https://doi.org/10.3389/fonc.2023.1154318
The role of nanotechnology for diagnostic and therapy strategies in lung cancer
Holder, J., Wilson, C. and Al-Yozbaki, M. 2022. The role of nanotechnology for diagnostic and therapy strategies in lung cancer. in: Jeremić, B. (ed.) Advances in Radiation Oncology in Lung Cancer Cham Springer.
Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics.
Padinharayil, Hafiza, Varghese, Jinsu, John, Mithun Chacko, Rajanikant, Golgodu Krishnamurthy, Wilson, Cornelia M, Al-Yozbaki, Minnatallah, Renu, Kaviyarasi, Dewanjee, Saikat, Sanyal, Rupa, Dey, Abhijit, Mukherjee, Anirban Goutam, Wanjari, Uddesh Ramesh, Gopalakrishnan, Abilash Valsala and George, Alex 2022. Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics. Genes & Diseases. 10 (3), pp. 960-989. https://doi.org/10.1016/j.gendis.2022.07.023
The role of nanotechnology for diagnostic and therapy strategies in lung cancer
Holder, J., Al-Yozbaki, M. and Wilson, C. 2022. The role of nanotechnology for diagnostic and therapy strategies in lung cancer. in: Medical Radiology Berlin, Heidelberg Springer. pp. 1-18
Advances in the lung cancer immunotherapy approaches
Padinharayil, H., Alappat, R., Joy, Liji Maria, Anilkumar, K., Wilson, C., George, A., Valsala Gopalakrishnan, A., Madhyastha, H., Ramesh, Thiyagarajan, Sathiyamoorthi, Ezhaveni, Lee, Jintae and Ganesan, R. 2022. Advances in the lung cancer immunotherapy approaches. Vaccines. 10 (11), p. 1963. https://doi.org/10.3390/vaccines10111963
Proteomic analysis of the extracellular vesicles derived from human hip joints affected by osteoarthritis
Tirnoveanu, A., Ahmed, S., Webb, R., Howland, K., Hurt, A., Wilson, C. and Mylona, A. 2022. Proteomic analysis of the extracellular vesicles derived from human hip joints affected by osteoarthritis.
Bioinformatics analysis of the interaction of miRNAs and piRNAs with human mRNA genes having di- and Trinucleotide repeats
Belkozhayev, A., Niyazova, Raigul, Wilson, C., Jainakbayev, Nurlan, Pyrkova, A., Ashirbekov, Y., Akimniyazova, A., Sharipov, K. and Ivashchenko, A. 2022. Bioinformatics analysis of the interaction of miRNAs and piRNAs with human mRNA genes having di- and Trinucleotide repeats. Genes. 13 (5), p. 800. https://doi.org/10.3390/genes13050800
Epigenetic differences in an identical genetic background modulate alternative splicing in A. thaliana.
Chaudhary, Saurabh, Jabre, Ibtissam and Syed, Naeem 2021. Epigenetic differences in an identical genetic background modulate alternative splicing in A. thaliana. Genomics. 113 (6), pp. 3476-3486. https://doi.org/S0888-7543(21)00312-8
Extracellular vesicles, stem cells and the role of miRNAs in neurodegeneration
Belkozhayev, Ayaz M., Al-Yozbaki, Minnatallah, George, Alex, Ye Niyazova, Raigul, Sharipov, Kamalidin O., Byrne, Lee J. and Wilson, Cornelia M. 2021. Extracellular vesicles, stem cells and the role of miRNAs in neurodegeneration. Current Neuropharmacology. 20 (8), pp. 1450-1478. https://doi.org/10.2174/1570159x19666210817150141
Epigenetic differences in an identical genetic background modulate alternative splicing in A. thaliana
Jabre, I., Chaudhary, S. and Syed, N. 2021. Epigenetic differences in an identical genetic background modulate alternative splicing in A. thaliana. Genomics. 113 (6). https://doi.org/https://doi.org/10.1016/j.ygeno.2021.08.006
Exploring the cytotoxic mechanisms of Pediocin PA-1 towards HeLa and HT29 cells by comparison to known bacteriocins: Microcin E492, enterocin heterodimer and Divercin V41.
Buss, G. and Wilson, C. 2021. Exploring the cytotoxic mechanisms of Pediocin PA-1 towards HeLa and HT29 cells by comparison to known bacteriocins: Microcin E492, enterocin heterodimer and Divercin V41. PLoS ONE. 16 (9), p. e0251951. https://doi.org/10.1371/journal.pone.0251951
The undiscovered potential of essential oils for treating SARS-CoV-2 (COVID-19)
Wilkin, P. J., Al-Yozbaki, M., George, A., Gupta, G.K. and Wilson, C.M. 2021. The undiscovered potential of essential oils for treating SARS-CoV-2 (COVID-19). Current Pharmaceutical Design. 26 (41), pp. 5261-5277. https://doi.org/10.2174/1381612826666201015154611
Balancing neurotrophin pathway and sortilin function: its role in human disease
Al-Yozbaki, M., Acha-Sagredo, A., George, A., Liloglou, T. and Wilson, C.M. 2021. Balancing neurotrophin pathway and sortilin function: its role in human disease. Biochim Biophys Acta Rev Cancer. 1874 (2). https://doi.org/10.1016/j.bbcan.2020.188429
Targeting DNA methyltransferases in non-small-cell lung cancer
Al-Yozbaki, M., Jabre, I., Syed, N. and Wilson, C. 2021. Targeting DNA methyltransferases in non-small-cell lung cancer. Seminars in Cancer Biology. https://doi.org/10.1016/j.semcancer.2021.01.005
Therapeutic potential of natural compounds in lung cancer
Al-Yozbaki, M., Wilkin, P., Gupta, G. and Wilson, C. 2021. Therapeutic potential of natural compounds in lung cancer. Current Medicinal Chemistry. 28 (39), pp. 7988-8002. https://doi.org/10.2174/0929867328666210322103906
Decoding co-/post-transcriptional complexities of plant transcriptomes and epitranscriptome using next-generation sequencing technologies
Reddy, A. S. N., Huang, J., Syed, N., Ben-Hur, A., Dong, S. and Gu, L. 2020. Decoding co-/post-transcriptional complexities of plant transcriptomes and epitranscriptome using next-generation sequencing technologies. Biochemical Society Transactions. https://doi.org/10.1042/BST20190492
Differential nucleosome occupancy modulates alternative splicing in Arabidopsis thaliana
Jabre, I., Chaudhary, S., Guo, W., Kalyna, M., Reddy, A. S. N., Chen, W., Zhang, R., Wilson, C. and Syed, N. 2020. Differential nucleosome occupancy modulates alternative splicing in Arabidopsis thaliana. New Phytologist. https://doi.org/10.1111/nph.17062
Applications and strategies in nanodiagnosis and nanotherapy in lung cancer
Woodman, C., Vundu, G., George, A. and Wilson, C. 2020. Applications and strategies in nanodiagnosis and nanotherapy in lung cancer. Seminars in Cancer Biology. https://doi.org/10.1016/j.semcancer.2020.02.009
Perspective on alternative splicing and proteome complexity in plants
Chaudhary, S., Jabre, I., Reddy, A., Staiger, D. and Syed, N. 2019. Perspective on alternative splicing and proteome complexity in plants. Trends in Plant Science. 24 (6), pp. 496-506. https://doi.org/10.1016/j.tplants.2019.02.006
Does co-transcriptional regulation of alternative splicing mediate plant stress responses?
Jabre, I., Reddy, A., Kalyna, M., Chaudhary, S., Khokhar, W., Byrne, L., Wilson, C. and Syed, N. 2019. Does co-transcriptional regulation of alternative splicing mediate plant stress responses? Nucleic Acids Research. 47 (6), pp. 2716-2726. https://doi.org/10.1093/nar/gkz121
Alternative splicing and protein diversity: plants versus animals
Chaudhry, S., Khokhar, W., Jabre, I., Reddy, A., Byrne, L., Wilson, C. and Syed, N. 2019. Alternative splicing and protein diversity: plants versus animals. Frontiers in Plant Science. 10 (708). https://doi.org/10.3389/fpls.2019.00708
Genome-wide identification of splicing quantitative trait loci (sQTLs) in diverse ecotypes of Arabidopsis thaliana
Khokhar, W., Hassan, M., Reddy, A., Chaudhary, S., Jabre, I., Byrne, L. and Syed, N. 2019. Genome-wide identification of splicing quantitative trait loci (sQTLs) in diverse ecotypes of Arabidopsis thaliana. Frontiers in Plant Science. 10 (1160). https://doi.org/10.3389/fpls.2019.01160
Genetic diversity and structure of northern populations of the declining coastal plant Eryngium maritimum
Ievina, B., Rostoks, N., Syed, N., Flavell, A. and Ievinsh, G. 2019. Genetic diversity and structure of northern populations of the declining coastal plant Eryngium maritimum. Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.. 73 (5), pp. 446-454. https://doi.org/10.2478/prolas-2019-0008
A comparative study between molecular and agro-morphological methods for describing genetic relationships in Tunisian faba bean populations
Syed, N. 2016. A comparative study between molecular and agro-morphological methods for describing genetic relationships in Tunisian faba bean populations. Journal of New Sciences: Agri & Biotech. 27 (8), pp. 1513-1518.
The role of endoproteolytic processing in neurodegeneration
Wilson, C., Mushtaq, G., Kamal, M. and Terro, F. 2016. The role of endoproteolytic processing in neurodegeneration. CNS and Neurological Disorders Drug Targets. 15. https://doi.org/10.2174/1871527315666160922163511
Challenges and strategies in precision medicine for non-small cell lung cancer
Wilson, C., Al-Akhrass, A. and Sacco, J. 2016. Challenges and strategies in precision medicine for non-small cell lung cancer. Current Pharmaceutical Design. 22. https://doi.org/10.2174/1381612822666160603014932
Comparative analysis of the drought-responsive transcriptome in soybean lines contrasting for canopy wilting
Prince, S., Joshi, T., Mutava, R., Syed, N., Joao Vitor, M., Patil, G., Song, L., Wang, J., Lin, L., Chen, W., Shannon, J., Valliyodan, B., Xu, D. and Nguyen, H. 2015. Comparative analysis of the drought-responsive transcriptome in soybean lines contrasting for canopy wilting. Plant Science. 240, pp. 65-78. https://doi.org/10.1016/j.plantsci.2015.08.017
Genome-Tagged Amplification (GTA): a PCR-based method to prepare sample-tagged amplicons from hundreds of individuals for next generation sequencing
Ho, T., Cardle, L., Xu, X., Bayer, M., Prince, K., Mutava, R., Marshall, D. and Syed, N. 2014. Genome-Tagged Amplification (GTA): a PCR-based method to prepare sample-tagged amplicons from hundreds of individuals for next generation sequencing. Molecular Breeding. 34 (3), pp. 977-988. https://doi.org/10.1007/s11032-014-0090-7
Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors
Wilson, C., Naves, T., Vincent, F., Lalloue, F. and Jauberteau, M. 2015. Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors.
Core clock, SUB1, and ABAR genes mediate flooding and drought responses via alternative splicing in soybean
Syed, N., Prince, S., Mutava, R., Patil, G., Li, S., Chen, W., Babu, V., Joshi, T., Khan, S. and Nguyen, H. 2015. Core clock, SUB1, and ABAR genes mediate flooding and drought responses via alternative splicing in soybean. Journal of Experimental Botany. https://doi.org/10.1093/jxb/erv407
Understanding abiotic stress tolerance mechanisms in soybean: a comparative evaluation of soybean response to drought and flooding stress
Mutava, R., Prince, S., Syed, N., Song, L., Valliyodan, B., Chen, W. and Nguyen, H. 2015. Understanding abiotic stress tolerance mechanisms in soybean: a comparative evaluation of soybean response to drought and flooding stress. Plant physiology and biochemistry : PPB / Société française de physiologie végétale. 86, pp. 109-20. https://doi.org/10.1016/j.plaphy.2014.11.010
Sequence-specific amplification polymorphisms (SSAPs): a multi-locus approach for analyzing transposon insertions
Syed, N. and Flavell, A. 2007. Sequence-specific amplification polymorphisms (SSAPs): a multi-locus approach for analyzing transposon insertions. Nature Protocols. 1 (6), pp. 2746-2752. https://doi.org/10.1038/nprot.2006.407
Genetic diversity analysis in Vicia species using retrotransposon-based SSAP markers
Sanz, A., Gonzalez, S., Syed, N., Suso, M., Saldaña, C. and Flavell, A. 2007. Genetic diversity analysis in Vicia species using retrotransposon-based SSAP markers. Molecular Genetics and Genomics. 278 (4), pp. 433-441. https://doi.org/10.1007/s00438-007-0261-x
Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis
Kalyna, M., Simpson, C., Syed, N., Lewandowska, D., Marquez, Y., Kusenda, B., Marshall, J., Fuller, J., Cardle, L., McNicol, J., Dinh, H., Barta, A. and Brown, J. 2012. Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis. Nucleic Acids Research. 40 (6), pp. 2454-2469. https://doi.org/10.1093/nar/gkr932
Alternative splicing mediates responses of the Arabidopsis circadian clock to temperature changes
James, A., Syed, N., Bordage, S., Marshall, J., Nimmo, G., Jenkins, G., Herzyk, P., Brown, J. and Nimmo, H. 2012. Alternative splicing mediates responses of the Arabidopsis circadian clock to temperature changes. The Plant Cell. 24 (3), pp. 961-981. https://doi.org/10.1105/tpc.111.093948
Alternative splicing in plants – coming of age
Syed, N., Kalyna, M., Marquez, Y., Barta, A. and Brown, J. 2012. Alternative splicing in plants – coming of age. Trends in Plant Science. 17 (10), pp. 616-623. https://doi.org/10.1016/j.tplants.2012.06.001
Thermoplasticity in the plant circadian clock: how plants tell the time-perature
James, A., Syed, N., Brown, J. and Nimmo, H. 2012. Thermoplasticity in the plant circadian clock: how plants tell the time-perature. Plant Signaling & Behavior. 7 (10), pp. 1219-1223. https://doi.org/10.4161/psb.21491
Inbred lines as testers for combining ability in cotton
Syed, W., Mehdi, S. and Syed, N. 1994. Inbred lines as testers for combining ability in cotton. Pakistan Journal of Scientific Research. 46, pp. 93-95.
Genetic study of lint percentage and staple length in cotton
Syed, W., Mehdi, S. and Syed, N. 1994. Genetic study of lint percentage and staple length in cotton. Pakistan Journal of Science. 46 (3-4), pp. 123-124.
Phenotypic recurrent selection for earliness in a random mated population of sunflower (Helianthus annuus L.)
Syed, N., Mehdi, S. and Syed, N. 1995. Phenotypic recurrent selection for earliness in a random mated population of sunflower (Helianthus annuus L.). Pakistan Journal of Scientific Research. 47 (3-4), pp. 62-65.
Two cycles of phenotypic recurrent selection for earliness in a random mated population of sunflower (Helianthus annuus L.)
Syed, N., Mehdi, S., Khan, I. and Syed, N. 1995. Two cycles of phenotypic recurrent selection for earliness in a random mated population of sunflower (Helianthus annuus L.). Science International (Lahore). 7, pp. 201-202.
Association of agronomic and economic characters of cotton
Syed, W., Mehdi, S. and Syed, N. 1995. Association of agronomic and economic characters of cotton. Pakistan Journal of Scientific Research. 47, pp. 46-49.
Fast and reliable genotype validation using microsatellite markers in Arabidopsis thaliana
Virk, P., Pooni, H., Syed, N. and Kearsey, M. 1999. Fast and reliable genotype validation using microsatellite markers in Arabidopsis thaliana. Theoretical and Applied Genetics. 98 (3-4), pp. 462-464. https://doi.org/10.1007/s001220051092
Genetic mapping of Sorghum bicolor (L.) Moench QTLs that control variation in tillering and other morphological characters
Hart, G., Schertz, K., Peng, Y. and Syed, N. 2001. Genetic mapping of Sorghum bicolor (L.) Moench QTLs that control variation in tillering and other morphological characters. Theoretical and Applied Genetics. 103 (8), pp. 1232-1242. https://doi.org/10.1007/s001220100582
Spontaneous gene flow and population structure in wild and cultivated chicory, Cichorium intybus L.
Kiær, L., Felber, F., Flavell, A., Guadagnuolo, R., Guiatti, D., Hauser, T., Olivieri, A., Scotti, I., Syed, N., Vischi, M., Wiel, C. and Jørgensen, R. 2009. Spontaneous gene flow and population structure in wild and cultivated chicory, Cichorium intybus L. Genetic Resources and Crop Evolution. 56 (3), pp. 405-419. https://doi.org/10.1007/s10722-008-9375-1
Molecular markers for the identification of resistance genes and marker-assisted selection in breeding wheat for leaf rust resistance
Vida, G., Gál, M., Uhrin, A., Veisz, O., Syed, N., Flavell, A., Wang, Z. and Bedő, Z. 2009. Molecular markers for the identification of resistance genes and marker-assisted selection in breeding wheat for leaf rust resistance. Euphytica. 170 (1-2), pp. 67-76. https://doi.org/10.1007/s10681-009-9945-0
Development of retrotransposon-based SSAP molecular marker system for study of genetic diversity in sea holly (Eryngium maritimum L.)
Levina, B., Syed, N., Flavell, A., Ievinsh, G. and Rostoks, N. 2010. Development of retrotransposon-based SSAP molecular marker system for study of genetic diversity in sea holly (Eryngium maritimum L.). Plant Genetic Resources. 8 (3), pp. 258-266. https://doi.org/10.1017/S1479262110000316
A hAT superfamily transposase recruited by the cereal grass genome
Muehlbauer, G., Bhau, B., Syed, N., Heinen, S., Cho, S., Marshall, D., Pateyron, S., Buisine, N., Chalhoub, B. and Flavell, A. 2006. A hAT superfamily transposase recruited by the cereal grass genome. Molecular Genetics and Genomics. 275 (6), pp. 553-563. https://doi.org/10.1007/s00438-006-0098-8
Genetics of quantitative traits in Arabidopsis thaliana
Kearsey, M., Pooni, H. and Syed, N. 2003. Genetics of quantitative traits in Arabidopsis thaliana. Heredity. 91 (5), pp. 456-464. https://doi.org/10.1038/sj.hdy.6800306
Optimising the construction of a substitution library in Arabidopsis thaliana using computer simulations
Syed, N., Pooni, H., Mei, M., Chen, Z. and Kearsey, M. 2004. Optimising the construction of a substitution library in Arabidopsis thaliana using computer simulations. Molecular Breeding. 13 (1), pp. 59-68. https://doi.org/10.1023/B:MOLB.0000012845.37366.b5
Molecular marker genotypes, heterozygosity and genetic interactions explain heterosis in Arabidopsis thaliana
Syed, N. and Chen, Z. 2005. Molecular marker genotypes, heterozygosity and genetic interactions explain heterosis in Arabidopsis thaliana. Heredity. 94 (3), pp. 295-304. https://doi.org/10.1038/sj.hdy.6800558
Ty1-copia retrotransposon-based SSAP marker development in cashew (Anacardium occidentale L.)
Syed, N., Sureshsundar, S., Wilkinson, M., Bhau, B., Cavalcanti, J. and Flavell, A. 2005. Ty1-copia retrotransposon-based SSAP marker development in cashew (Anacardium occidentale L.). Theoretical and Applied Genetics. 110 (7), pp. 1195-1202. https://doi.org/10.1007/s00122-005-1948-1
A detailed linkage map of lettuce based on SSAP, AFLP and NBS markers
Syed, N., Sørensen, A., Antonise, R., Wiel, C., Linden, C., van 't Westende, W., Hooftman, D., Nijs, H. and Flavell, A. 2006. A detailed linkage map of lettuce based on SSAP, AFLP and NBS markers. Theoretical and Applied Genetics. 112 (3), pp. 517-527. https://doi.org/10.1007/s00122-005-0155-4
Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors.
Wilson, C., Naves, T., Vincent, F., Melloni, B., Bonnaud, F., Lalloue, F. and Jauberteau, M. 2014. Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors. Journal of Cell Science (JCS). 127 (18), pp. 3983-3997. https://doi.org/10.1242/jcs.149336
Genetic mapping and QTL analysis of fiber-related traits in cotton (Gossypium)
Mei, M., Syed, N., Gao, W., Thaxton, P., Smith, C., Stelly, D. and Chen, Z. 2004. Genetic mapping and QTL analysis of fiber-related traits in cotton (Gossypium). Theoretical and Applied Genetics. 108 (2), pp. 280-291. https://doi.org/10.1007/s00122-003-1433-7