Is there a role for stem cell therapy in erectile dysfunction secondary to cavernous nerve injury? Network meta-analysis from animal studies and human trials

Journal article

Wani, Mudassir M., Rai, Bhavan P., Webb, W. and Madaan, S. 2022. Is there a role for stem cell therapy in erectile dysfunction secondary to cavernous nerve injury? Network meta-analysis from animal studies and human trials. Therapeutic Advances in Urology. 14, p. 175628722210869. https://doi.org/10.1177/17562872221086999

Publication dates
Authors	Wani, Mudassir M., Rai, Bhavan P., Webb, W. and Madaan, S.
Abstract	Introduction: We carried out systematic review and network meta-analysis to investigate the role of stem cell therapy (SCT) in the management of erectile dysfunction (ED) secondary to cavernous nerve injury in rats and post-radical prostatectomy (RP) in humans. Patients and Methods: The protocol was registered with PROSPERO database. We searched studies analyzing the efficacy of SCT for ED due to bilateral cavernous nerve injury (BCNI) in rats using Healthcare Databases Advanced Search (HDAS) Export software (MEDLINE, EMBASE, Scopus) from inception to September 2020. The outcome measurements, for 29 animal studies, were intracavernosal pressure (ICP), ICP/MAP (mean arterial pressure) ratio, and histological/molecular changes. All three available human trials evaluating SCT in post-RP ED were assessed for International Index for Erectile Function (IIEF) Score and Erection Hardness Score (EHS). Results: For ICP measurement, animal studies were divided into adipose-derived stem cells (ADSCs) subgroup and bone marrow–derived stem cells (BMSCs) subgroup. Pooled analysis of these studies showed a beneficial effect of SCT in improving erectile function in rats with BCNI using network meta-analysis (95% confidence interval, CI; p < 0.001). There was an increase in ICP/MAP ratio in stem cell groups (including co-intervention) compared with control BCNI group. Histological and molecular evaluation of penile tissue revealed an increase in neuronal nitric oxide synthase (nNOS), smooth muscle content, and anti-apoptotic activity. Human trials revealed improved IIEF (70–150% from baseline at 6 months) and EHS (80–200% from baseline). Conclusion: Our results confirm that SCT does improve the erectile function in rats having cavernous nerve injury. Similarly, early human results have shown promising results. PROSPERO registration ID: CRD42020201343.
Keywords	Urology
Year	2022
Journal	Therapeutic Advances in Urology
Journal citation	14, p. 175628722210869
Publisher	SAGE Publications
ISSN	1756-2872
	1756-2880
Digital Object Identifier (DOI)	https://doi.org/10.1177/17562872221086999
Official URL	https://journals.sagepub.com/doi/10.1177/17562872221086999
Print	29 Mar 2022
Online	29 Mar 2022
Publication process dates
Accepted	07 Mar 2022
Deposited	06 Apr 2022
Publisher's version	17562872221086999.pdf License CC BY-ND 4.0 File Access Level Open
Output status	Published
Additional information	Publications router: Date 2022-03-29 of type 'publication_date' with format 'electronic' included in notification Publications router: Date 2022-03-29 of type 'epub' included in notification

Permalink -

https://repository.canterbury.ac.uk/item/90w41/is-there-a-role-for-stem-cell-therapy-in-erectile-dysfunction-secondary-to-cavernous-nerve-injury-network-meta-analysis-from-animal-studies-and-human-trials

Download files

Publisher's version

	17562872221086999.pdf
License: CC BY-ND 4.0
File access level: Open

71
total views
58
total downloads
4
views this month
2
downloads this month

Export as

Related outputs

De novo stone formation in ureteric stump post-nephrectomy

Ahmed Mohamed, Omer Abdalla, Banan Omer, Madaan, S. and Seshadri Sriprasad 2023. De novo stone formation in ureteric stump post-nephrectomy. Journal of Endoluminal Endourology. https://doi.org/10.22374/jeleu.v6i1.158

Collision metastasis from prostate adenocarcinoma and pancreatic ductal adenocarcinoma to a lung nodule

Mohamed, A., Yao, M., Saw, S., Clark, A. and Madaan, S. 2023. Collision metastasis from prostate adenocarcinoma and pancreatic ductal adenocarcinoma to a lung nodule. JRSM Open. 14 (3). https://doi.org/10.1177/20542704231153562

The availability, cost, limitations, learning curve and future of robotic systems in urology and prostate cancer surgery

Hughes, T., Rai, B., Madaan, S., Chedgy, E. and Somani, B. 2023. The availability, cost, limitations, learning curve and future of robotic systems in urology and prostate cancer surgery. Journal of Clinical Medicine. 12 (6), p. 2268. https://doi.org/10.3390/jcm12062268

Comparison of outcomes of active surveillance in intermediate-risk versus low-risk localised prostate cancer patients: A systematic review and meta-analysis

Mukherjee, S., Papadopoulos, D., Norris, J.M., Wani, M. and Madaan, S. 2023. Comparison of outcomes of active surveillance in intermediate-risk versus low-risk localised prostate cancer patients: A systematic review and meta-analysis. Journal of Clinical Medicine. 12 (7), p. 2732. https://doi.org/10.3390/jcm12072732

Venous thromboembolism (VTE) in post-prostatectomy patients

Wani, M., Al-Mitwalli, A., Mukherjee, S., Nabi, G., Somani, B.K., Abbaraju, J. and Madaan, S. 2023. Venous thromboembolism (VTE) in post-prostatectomy patients. Journal of Clinical Medicine. 12 (12), p. 3979.

Urinary bladder melanosis with complete resolution case report

Mateescu, D., Dahir, H., Goel, A., Ray, E. and Madaan, S. 2023. Urinary bladder melanosis with complete resolution case report. African Journal of Urology. 29 (37).

What is new in the management of high-risk localized prostate cancer?

Wani, M. and Madaan, S. 2023. What is new in the management of high-risk localized prostate cancer? Journal of Clinical Medicine. 12 (2), p. 455. https://doi.org/10.3390/jcm12020455

Culture‑proven disseminated Mycobacterium Bovis infection (BCG‑Osis) following intravesical BCG immunotherapy in a patient with bladder carcinoma‑in‑situ: ‘Case report’.

Ahmed Ghonaimy, Tariq Qadeer, Sudhir Lohani, John Schofield and Madaan, S. 2022. Culture‑proven disseminated Mycobacterium Bovis infection (BCG‑Osis) following intravesical BCG immunotherapy in a patient with bladder carcinoma‑in‑situ: ‘Case report’. African Journal of Urology. 28 (3). https://doi.org/10.1186/s12301-022-00270-1

10-minute consultation - Visible haematuria

Madaan, A., Gandhi, N. and Madaan, S. 2022. 10-minute consultation - Visible haematuria. British Medical Journal (BMJ). 2022 (376), p. e067395. https://doi.org/10.1136/bmj-2021-067395

Multiparametric ultrasound versus multiparametric MRI to diagnose prostate cancer (CADMUS): a prospective, multicentre, paired-cohort, confirmatory study

Grey, A., Scott, R., Shah, B., Acher, P., Liyanage, S., Pavlou, M., Omar, R., Chinegwundoh, F., Patki, P., Sha,h T., Hamid, S., Ghei, M., Gilbert, K., Brew-Graves, C., Arumainayagam, N., Chapman, A., Freeman, A., Eldred-Evans, D., Bertoncelli-Tanaka, M., Tam, H., Ramachandran, N., Madaan, S., Winkler, M., Arya, M., Emberton, M. and Ahmed, H. U. 2022. Multiparametric ultrasound versus multiparametric MRI to diagnose prostate cancer (CADMUS): a prospective, multicentre, paired-cohort, confirmatory study. The Lancet. Oncology. 23 (3), pp. 428-438. https://doi.org/10.1016/S1470-2045(22)00016-X

Medical statistics for urologists: Part 2 - Probability and hypothesis testing

Vyas, R., Madaan, A. and Madaan, S. 2022. Medical statistics for urologists: Part 2 - Probability and hypothesis testing. Urology News.

The safety and feasibility of simultaneous robotic repair of an inguinal hernia during robotic-assisted laparoscopic prostatectomy: a systematic review and meta-analysis

Motaz Melhem, Javid Burki, Omar Algurabi, Sayed Gilani, Faisal Ghumman, Matin Sheriff, Mudassir Wani, Ra’ed Haddad and Madaan, S. 2022. The safety and feasibility of simultaneous robotic repair of an inguinal hernia during robotic-assisted laparoscopic prostatectomy: a systematic review and meta-analysis. Scandinavian Journal of Urology. 56 (3), pp. 197-205. https://doi.org/10.1080/21681805.2022.2065358

Factors causing variation in WHO surgical safety checklist effectiveness - A rapid scoping review

Mudassir M. Wani, John H.V. Gilbert, Ciraj Ali Mohammad and Madaan, S. 2022. Factors causing variation in WHO surgical safety checklist effectiveness - A rapid scoping review. Journal of Patient Safety. 18 (8), pp. 1150-1139. https://doi.org/10.1097/PTS.0000000000001035

Medical statistics for urologists: part 3 – diagnostic testing

Madaan, A., Vyas, R. and Madaan, S. 2022. Medical statistics for urologists: part 3 – diagnostic testing. Urology News. 26 (5).

Urological implications associated with the use of recreational drugs: A narrative review

Wani, M., Hamdoon, M., Dewar, G., Buakuma, P. and Madaan, S. 2022. Urological implications associated with the use of recreational drugs: A narrative review. Turkish Journal of Urology. 48 (4), pp. 254-261.

Are staging bone scans necessary in patients with T3a prostate cancer? A multicentre study

Danielle Whiting, Simone Giona, Mark Yao, Roa Hassan, Hong Doan, Rustam Karanjia, James Hicks, Ben Eddy, Madaan, S. and Simon Bott 2022. Are staging bone scans necessary in patients with T3a prostate cancer? A multicentre study. Journal of Clinical Urology. https://doi.org/10.1177/20514158221137110

Nurse‐led one stop hematuria clinic: Outcomes from 2,714 patients

Madaan, Anika, Kuusk, Teele, Hamdoon, Musaab, Elliott, Angela, Pearce, Dianne and Madaan, S. 2021. Nurse‐led one stop hematuria clinic: Outcomes from 2,714 patients. BJUI Compass. 2 (6), pp. 385-394. https://doi.org/10.1002/bco2.100

Establishing a consensus for the management of non-metastatic castration-resistant prostate cancer in the UK

Payne, Heather, Bahl, Amit, Cornford, Phil, Crabb, Simon, Drudge-Coates, Lawrence, Madaan, Sanjeev, McMenemin, Rhona and Sundar, Santhanam 2021. Establishing a consensus for the management of non-metastatic castration-resistant prostate cancer in the UK. Springer Nature.

Medical statistics for urologists: part 1

Vyas, R., Madaan, A. and Madaan, S. 2021. Medical statistics for urologists: part 1. Urology News. 25 (6), pp. 6-8.

Embryology, anatomy and physiology of the kidney and ureters

Paul Sturch, Sanjeev Madaan and Seshadri Sriprasad 2021. Embryology, anatomy and physiology of the kidney and ureters. in: Karl H. Pang, Nadir I. Osman, James W. F. Catto and Christopher R. Chapple (ed.) Basic Urological Sciences CRC Press.

Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme

Ruth E. Langley, Duncan C. Gilbert, Trinh Duong, Noel W. Clarke, Matthew Nankivell, Stuart D. Rosen, Stephen Mangar, Archie Macnair, Subramanian Kanaga Sundaram, Marc E. Laniado, Sanjay Dixit, Sanjeev Madaan, Caroline Manetta, Alvan Pope, Christopher D. Scrase, Stephen Mckay, Iqtedar A. Muazzam, Gerald N. Collins, Jane Worlding, Simon T. Williams, Edgar Paez, Angus Robinson, Jonathan McFarlane, John V. Deighan, John Marshall, Silvia Forcat, Melanie Weiss, Roger Kockelbergh, Abdulla Alhasso, Howard Kynaston and Mahesh Parmar 2021. Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme. The Lancet. 397 (10272), pp. 581-591. https://doi.org/10.1016/S0140-6736(21)00100-8

Active surveillance - Is it feasible for intermediate-risk localised prostate cancer?

Subhabrata Mukherjee, Ioannis Promponas, Neophytos Petrides, Dafader Hossain, Jayasimha Abbaraju and Sanjeev Madaan 2021. Active surveillance - Is it feasible for intermediate-risk localised prostate cancer? European Urology Open Science. 24, pp. 17-24. https://doi.org/10.1016/j.euros.2020.12.005

Mistaken administration of a repeat loading dose of Degarelix leading to acute psychosis

Musaab Hamdoob, Maria Satchi, Fay Fawke and Sanjeev Madaan 2021. Mistaken administration of a repeat loading dose of Degarelix leading to acute psychosis. JRSM Open. 12 (2). https://doi.org/10.1177/2054270420983105

Bladder-to-bladder metastasis: gallbladder cancer metastasising to the urinary bladder

S. Mukherjee, J. Abbaraju, G. Russell and S. Madaan 2021. Bladder-to-bladder metastasis: gallbladder cancer metastasising to the urinary bladder. Annals of the Royal College of Surgeons of England. 103 (4), pp. e116-e119. https://doi.org/10.1308/rcsann.2020.7048

Challenges in urology

Pandian, S., Sriprasad, S. and Madaan, S. 2021. Challenges in urology. Pulse. 7, pp. 68-72.

Complications after radical nephrectomy according to age: analysis from the British Association of Urological Surgeons Nephrectomy Audit

Danielle Whiting, Benjamin Challacombe, Sanjeev Madaan, Sarah Fowler, Richard Napier-Hemy and Seshadri Sriprasad 2021. Complications after radical nephrectomy according to age: analysis from the British Association of Urological Surgeons Nephrectomy Audit. Journal of Endourology, JE Case Reports, and Videourology. https://doi.org/10.1089/end.2021.0165

Clinical impact of the Predict Prostate risk communication tool in men newly diagnosed with non-metastatic prostate cancer: a multi-centre randomised controlled trial

David Thurtle, Val Jenkins, Alex Freeman, Mike Pearson, Gabriel Recchia, Priya Tamer, Kelly Leonard, Paul Pharoah, Jonathan Aning, Sanjeev Madaan, Chee Goh, Serena Hilman, Stuart McCracken, Petre Cristian Ilie, Henry Lazarowicz and Vincent Gnanapragasam 2021. Clinical impact of the Predict Prostate risk communication tool in men newly diagnosed with non-metastatic prostate cancer: a multi-centre randomised controlled trial. European Urology. 80 (5), pp. 661-669. https://doi.org/10.1016/j.eururo.2021.08.001

Is Thulium laser enucleation of prostate an alternative to Holmium and TURP surgeries? - A systematic review

Mudassir M. Wani, Seshadri Sriprasad, Tahir Bhat and Sanjeev Madaan 2020. Is Thulium laser enucleation of prostate an alternative to Holmium and TURP surgeries? - A systematic review. Turkish Journal of Urology. 46 (6), pp. 419-426. https://doi.org/10.5152/tud.2020.20202

Laparoscopic pyeloplasty and pyelolithotomy in a pelvic kidney

Musaab Hamdoon, Danielle Whiting, Mohamed Breish, Seshadri Sriprasad and Sanjeev Madaan 2020. Laparoscopic pyeloplasty and pyelolithotomy in a pelvic kidney. Urology Video Journal.

Spontaneous haemorrhage of an adrenal angiomyolipoma: case report

Danielle Whiting, Ian Rudd, Amit Goel, Seshadri Sriprasad and Sanjeev Madaan 2019. Spontaneous haemorrhage of an adrenal angiomyolipoma: case report. African Journal of Urology. 25 (4). https://doi.org/10.1186/s12301-019-0006-1

The clinical impact of Hexylaminolevulinate-Blue Light Cystoscopy on non-muscle invasive bladder cancer (NMIBC) recurrence and progression: A critical review

Omer Abdalla, Seshadri Sriprasad and Sanjeev Madaan 2019. The clinical impact of Hexylaminolevulinate-Blue Light Cystoscopy on non-muscle invasive bladder cancer (NMIBC) recurrence and progression: A critical review. Journal of Urology and Nephrology Studies. https://doi.org/10.32474/JUNS.2019.01.000123

Non-muscle-invasive clear cell carcinoma of the urinary bladder: Is cystectomy necessary?

Tamani Jayawardhana, Hossam Alsayed, Amit Goel and Sanjeev Madaan 2019. Non-muscle-invasive clear cell carcinoma of the urinary bladder: Is cystectomy necessary? BMJ Case Reports. https://doi.org/10.1136/bcr-2018-226928

BOXIT-A randomised phase III placebo-controlled trial evaluating the addition of Celecoxib to standard treatment of transitional cell carcinoma of the bladder (CRUK/07/004)

John D Kelly, Wei Shen Tan, Nuria Porta, Hugh Mostafid, Robert Huddart, Andrew Protheroe, Richard Bogle, Jane Blazeby, Alison Palmer, Jo Cresswell, Mark Johnson, Richard Brough, Sanjeev Madaan, Stephen Andrews, Clare Cruickshank, Stephanie Burnett, Lauren Maynard, Emma Hall and BOXIT Investigators 2019. BOXIT-A randomised phase III placebo-controlled trial evaluating the addition of Celecoxib to standard treatment of transitional cell carcinoma of the bladder (CRUK/07/004). European Urology. 75 (4), pp. 593-601. https://doi.org/10.1016/j.eururo.2018.09.020

Radiofrequency-induced thermo-chemotherapy effect versus a second course of Bacillus Calmette-Guérin or institutional standard in patients with recurrence of non-muscle-invasive bladder cancer following induction or maintenance Bacillus Calmette-Guérin therapy (HYMN): A phase III, open-label, randomised controlled trial

Tan WS, Panchal A, Buckley L, Devall AJ, Loubière LS, Pope AM, Feneley MR, Cresswell J, Issa R, Mostafid H, Madaan S, Bhatt R, McGrath J, Sangar V, Griffiths TRL, Page T, Hodgson D, Datta SN, Billingham LJ and Kelly JD 2019. Radiofrequency-induced thermo-chemotherapy effect versus a second course of Bacillus Calmette-Guérin or institutional standard in patients with recurrence of non-muscle-invasive bladder cancer following induction or maintenance Bacillus Calmette-Guérin therapy (HYMN): A phase III, open-label, randomised controlled trial. European Urology. 75 (1), pp. 63-71. https://doi.org/10.1016/j.eururo.2018.09.005

Systematic review of surgery of solitary metastasis post nephrectomy and its survival.

Lava Krishna Kannappa, Khalid Hureibi, Jaisimha Abbaraju, Sanjeev Madaan and Seshadri Sriprasad 2018. Systematic review of surgery of solitary metastasis post nephrectomy and its survival. International Journal of Surgery and Surgical Sciences (IJSSS). 6 (2).

Intravesical radiofrequency-induced chemohyperthermia for carcinoma in situ of the urinary bladder: A retrospective multicentre study

van Valenberg, FJP, Kajtazovic, A, Canepa, G, Lüdecke, G, Kilb, JI, Aben, KKH, Nativ, O, Madaan, S, Ayres, B, Issa, R and Witjes, JA 2018. Intravesical radiofrequency-induced chemohyperthermia for carcinoma in situ of the urinary bladder: A retrospective multicentre study. Bladder Cancer. 4 (4), pp. 365-376. https://doi.org/10.3233/BLC-180187

History of prostate biopsy – part 2

Shiv Kumar Pandian, Mohamed Hammadeh, Ben Challacombe, Oussama Elhage, Rick Popert and Sanjeev Madaan 2018. History of prostate biopsy – part 2. Urology News. 22 (6).

Spontaneous rupture of a renal artery pseudoaneurysm with no precipitating risk factor

Marios Hadjipavlou, Jayasimha Abbaraju, Viktor Serafimov and Sanjeev Madaan 2018. Spontaneous rupture of a renal artery pseudoaneurysm with no precipitating risk factor. JRSM Open. https://doi.org/10.1177/2054270418758568

Radical surgery for upper tract urothelial carcinoma

Reekhaye, A. and Madaan, S. 2018. Radical surgery for upper tract urothelial carcinoma. BJUI.

History of prostate biopsy – part 1

Shiv Kumar Pandian, Mohamed Hammadeh, Ben Challacombe, Rick Popert and Sanjeev Madaan 2018. History of prostate biopsy – part 1. Urology News.

The CADMUS trial – Multi-parametric ultrasound targeted biopsies compared to multi-parametric MRI targeted biopsies in the diagnosis of clinically significant prostate cancer

Alistair Grey, Rebecca Scott, Susan Charmane, Janvan der Meulene, Peter Frinking, Peter Acher, Sidath Liyanageh, Sanjeev Madaan, Gabriel Constantinescu, Bina Shah, Chris Brew Graves, Alex Freeman, Charles Jameson, Navin Ramachandran, Mark Emberton, Manit Aryab and Hashim U.Ahmedab 2018. The CADMUS trial – Multi-parametric ultrasound targeted biopsies compared to multi-parametric MRI targeted biopsies in the diagnosis of clinically significant prostate cancer. Contemporary Clinical Trials. 66, pp. 86-92. https://doi.org/10.1016/j.cct.2017.10.011

A review of the contemporary management of upper urinary tract urothelial carcinoma

Abhishek Reekhay, Seshadri Sriprasad and Sanjeev Madaan 2017. A review of the contemporary management of upper urinary tract urothelial carcinoma. Journal of Clinical Urology. 11 (1), pp. 51-57. https://doi.org/10.1177/2051415817717906

Small renal masses – diagnosis and management

Reekhaye, A. and Madaan, S. 2017. Small renal masses – diagnosis and management. Urology News. 21 (2), pp. 17-18.

Patient management – brief overview of prostate cancer: diagnosis and management

Brunning, C., Reekhaye, A. and Madaan, S. 2017. Patient management – brief overview of prostate cancer: diagnosis and management. Foundation Years Journal. 11 (4), p. 6.

Patient management – non muscle invasive bladder cancer

Buakuma, P., Dewar, G., Pandian, S. and Madaan, S. 2017. Patient management – non muscle invasive bladder cancer. Foundation Years Journal. 11 (4), p. 45.

Lower urinary tract symptoms in an older man

Vedanayagam, M., Kumar, A. and Madaan, S. 2017. Lower urinary tract symptoms in an older man. British Medical Journal (BMJ). 357. https://doi.org/10.1136/bmj.j1493

An update on antibiotic prophylaxis in trans-rectal ultra-sound (TRUS) guided prostate biopsy

Hossain, D. M. S., Jayawardhana, T. and Madaan, S. 2016. An update on antibiotic prophylaxis in trans-rectal ultra-sound (TRUS) guided prostate biopsy. Urology News. 21 (1), pp. 25-27.

Quality-of-life outcomes from the Prostate Adenocarcinoma: TransCutaneous Hormones (PATCH) trial evaluating luteinising hormone-releasing hormone agonists versus transdermal oestradiol for androgen suppression in advanced prostate cancer

Gilbert, D. C., Duong, T., Kynaston, H. G., Alhasso, A. A., Cafferty, F. H., Rosen, S. D., Kanaga-Sundaram, S., Dixit, S., Laniado, M., Madaan, S., Collins, G., Pope, A., Welland, A., Nankivell, M., Wassersug, R., Parmar, M. K. B., Langley, R. E. and Abel, P. D. 2016. Quality-of-life outcomes from the Prostate Adenocarcinoma: TransCutaneous Hormones (PATCH) trial evaluating luteinising hormone-releasing hormone agonists versus transdermal oestradiol for androgen suppression in advanced prostate cancer. BJU International. 119, p. 667–675. https://doi.org/10.1111/bju.13687

Is extended pelvic lymph node dissection for prostate cancer the only recommended option? A systematic over-view of the literature

Rees, T., Raison, N., Sheikh, M. I., Jaffry, Z., Madaan, S., Challacombe, B., Ahmed, K. and Dasgupta, P. 2016. Is extended pelvic lymph node dissection for prostate cancer the only recommended option? A systematic over-view of the literature. Turkish Journal of Urology. 42 (4), pp. 240-6. https://doi.org/10.5152/tud.2016.52893

NICE prostate cancer quality standards

Madaan, S. and Reekhaye, A. 2016. NICE prostate cancer quality standards. Journal of Clinical Urology. 9 (5), p. 295–299. https://doi.org/10.1177/2051415816642694

Active surveillance for prostate cancer

Reekhaye, A. and Madaan, S. 2016. Active surveillance for prostate cancer. Journal of Cancer Clinical Trials. 1 (2).

Use of Clavien-Dindo classification in urology part 2 – upper tract

Sanjeev Madaan and Dafadar MS Hossain 2016. Use of Clavien-Dindo classification in urology part 2 – upper tract. Urology News. 20 (4).

Use of Clavien-Dindo classification in urology part 1 – pelvic surgery

Sanjeev Madaan and Dafadar MS Hossain 2016. Use of Clavien-Dindo classification in urology part 1 – pelvic surgery. Urology News. 20 (3).

Survivorship and prostate cancer: the TrueNTH Supported Self-Management programme

Sanjeev Madaan, Abhishek Reekhaye and Jonathan McFarlane 2016. Survivorship and prostate cancer: the TrueNTH Supported Self-Management programme. Trends in Urology and Men's Health. 7 (1), pp. 21-24. https://doi.org/10.1002/tre.502

Widespread lytic lesions—A metastatic or vasculitic process?

Fahd Khan, Srinivasan Srirangan, Yasser El Miedany and Sanjeev Madaan 2016. Widespread lytic lesions—A metastatic or vasculitic process? International Journal of Surgery Case Reports. 18, pp. 18-20. https://doi.org/10.1016/j.ijscr.2015.11.023

Who was the father of the nomogram?

Hadjipavlou, M., Philippou, Y., Sriprasad, S. and Madaan, S. 2015. Who was the father of the nomogram? European Urology Supplements. 14 (2), p. e997. https://doi.org/10.1016/s1569-9056(15)60985-x

Active surveillance for low-risk prostate cancer

Marios Hadjipavlou, John Promponas and Sanjeev Madaan 2015. Active surveillance for low-risk prostate cancer. Journal of Clinical Urology. 8 (6), pp. 420-428. https://doi.org/10.1177/2051415815592816

The Ellik Evacuator: Evolution in emptying

A.M. Tasleem, F. Khan, W. Mahmalji, S. Madaan, I. Dickinson and S. Sriprasad 2014. The Ellik Evacuator: Evolution in emptying. European Urology Supplements. (13), p. e328. https://doi.org/10.1016/S1569-9056(14)60323-7

The regulation of urologists through time: A work in progress

Ali Tasleem, Wasim Mahmalji, Marios Hadjipavlou, Sanjeev Madaan, Ian Dickinson and Seshadri Sriprasad 2014. The regulation of urologists through time: A work in progress. European Urology Supplements. 13, p. e335.

Patient management: urinary retention

Seth, J. H., Madaan, S. and Iftikhar Ghumman, F. 2014. Patient management: urinary retention. Foundation Years Journal. 8 (10), p. 46.

A late presentation of isolated lymph node tuberculosis postintravesical BCG therapy for superficial bladder cancer: a novel case

Tasleem, A. M., Varga, B., Mahmalji, W. and Madaan, S. 2014. A late presentation of isolated lymph node tuberculosis postintravesical BCG therapy for superficial bladder cancer: a novel case. BMJ Case Reports. 2014. https://doi.org/10.1136/bcr-2014-204037

Evaluation of the pressure leak test in increasing the lifespan of flexible ureteroscopes

F. Khan, S. Mukhtar, H. Marsh, F. Anjum, S. Madaan, I. K. Dickinson and S. Sriprasad 2013. Evaluation of the pressure leak test in increasing the lifespan of flexible ureteroscopes. International Journal of Clinical Practice. 27 (10), pp. 1040-1043. https://doi.org/10.1111/ijcp.12149

Prostate cancer with metastases to the kidney: a rare manifestation of a common disease

Fahd Khan, Wasim Mahmalji, Seshadri Sriprasad and Sanjeev Madaan 2013. Prostate cancer with metastases to the kidney: a rare manifestation of a common disease. BMJ Case Reports. https://doi.org/10.1136/bcr-2012-008388

Urological complications of inguinal hernia surgery

S. Shah, H. Marsh, M.S. Khan, A. Shah and S. Madaan 2013. Urological complications of inguinal hernia surgery. Scottish Medical Journal. 58 (2), pp. 119-123. https://doi.org/10.1177/0036933013482671

Fournier's gangrene associated with intradermal injection of cocaine

Fahd Khan, Saheel Mukhtar, Faqar Anjuml, Bharati Tripathi, Seshadri Sriprasad, Ian K. Dickinson and Sanjeev Madaan 2013. Fournier's gangrene associated with intradermal injection of cocaine. Journal of Sexual Medicine. 10 (4), pp. 1184-1186. https://doi.org/10.1111/jsm.12055

Bipolar transurethral resection of prostate: Current status in the management of bladder outflow obstruction

M. Bolgeri, S. Naji, A. Sahai, F. Anjum, S. Madaan, S. Sriprasad and I. Dickinson 2012. Bipolar transurethral resection of prostate: Current status in the management of bladder outflow obstruction. Journal of Clinical Urology. 5 (3), pp. 105-110. https://doi.org/10.1016/j.bjmsu.2011.06.004

Benign schwannoma of seminal vesicle presenting as haematospermia

Faqar Anjum, Senthy Sellaturay, Phauda Thebe, Ian Dickinson, Seshadri Sriprasad and Sanjeev Madaan 2012. Benign schwannoma of seminal vesicle presenting as haematospermia. Journal of Clinical Urology. 5 (3), pp. 137-139. https://doi.org/10.1016/j.bjmsu.2011.06.003

Submucosal ureteric calculus mimicking transitional cell carcinoma

Madaan, S., Bardapure, M., Nagarajan, M. and Biyani, C. S. 2010. Submucosal ureteric calculus mimicking transitional cell carcinoma. International Journal of Clinical Practice. 64 (1), pp. 131-133. https://doi.org/10.1111/j.1742-1241.2006.01070.x

A giant bladder calculus with a synchronous giant secondary vaginal stone: a case report

Miah, S., Madaan, S., Khan, M., Urwin, G. and Stower, M. 2009. A giant bladder calculus with a synchronous giant secondary vaginal stone: a case report. Current Urology. 2 (4), pp. 206-207. https://doi.org/10.1159/000209835

Segmental testicular infarction: conservative management is feasible and safe

Sanjeev Madaan, Steven Joniau, Katrien Klockaerts, Liesbeth DeWever, Evelyne Lerut, Raymond Oyen and Hendrik Van Poppel 2008. Segmental testicular infarction: conservative management is feasible and safe. European Urology. 52 (2), pp. 441-445. https://doi.org/10.1016/j.eururo.2007.03.061

Segmental testicular infarction. Conservative management is feasible and safe: part 2

Sanjeev Madaan, Steven Joniau, Katrien Klockaerts, Liesbeth DeWever, Evelyne Lerut, Raymond Oyen and Hendrik Van Poppel 2007. Segmental testicular infarction. Conservative management is feasible and safe: part 2. European Urology. 53 (3), pp. 656-658. https://doi.org/10.1016/j.eururo.2007.03.062

Key clinical issues in renal cancer: a challenge for proteomics

Rosamonde E. Bank, Rachel A. Craven, Patricia Harnden, Sanjeev Madaan, Adrian Joyce and Peter J. Selby 2007. Key clinical issues in renal cancer: a challenge for proteomics. World Journal of Urology. 25, pp. 537-556. https://doi.org/10.1007/s00345-007-0199-y

Unusual squamous cell carcinoma of the scrotum arising from a well healed, innocuous scar of an infertility procedure: a case report

Sanjeev Kotwal, Sanjeev Madaan, Stephen Prescott, Sameer Chilka and Peter Whelan 2007. Unusual squamous cell carcinoma of the scrotum arising from a well healed, innocuous scar of an infertility procedure: a case report. Annals of the Royal College of Surgeons of England. 89 (5), pp. W17-W-19. https://doi.org/10.1308/147870807X188498

Limitations of extracorporeal shock wave lithotripsy

Madaan, S. and Joyce, A. 2007. Limitations of extracorporeal shock wave lithotripsy. Current Opinion in Urology. 17 (2), pp. 109-113. https://doi.org/10.1097/MOU.0b013e32802b70bc

Omental metastasis with malignant ascites: an unusual manifestation of prostatic adenocarcinoma

Sanjeev Madaan, Victor Palit, Patricia Gudgeon and Chandra Shekhar Biyani 2007. Omental metastasis with malignant ascites: an unusual manifestation of prostatic adenocarcinoma. Canadian Urological Association Journal. 1 (3). https://doi.org/10.5489/cuaj.86

Ureteric complications of renal transplantation: the impact of the double J stent and the anterior extravesical ureteroneocystostomy

S. Guleria, R .Chahal, S. Madaan, H. C. Irving, C. G. Newstead, S. G. Pollard and J. P .A. Lodge 2005. Ureteric complications of renal transplantation: the impact of the double J stent and the anterior extravesical ureteroneocystostomy. Transplantation Proceedings. 37 (2), pp. 1054-1056. https://doi.org/10.1016/j.transproceed.2004.12.123

A complex caliceal-cutaneous and caliceal-peritoneal fistula in a renal transplant patient: a case for conservative management

Rohit Chahal, Sanjeev Madaan, Sandeep Guleria, J Peter A Lodge and John A Spencer 2004. A complex caliceal-cutaneous and caliceal-peritoneal fistula in a renal transplant patient: a case for conservative management. International Urology and Nephrology. 36, pp. 245-247. https://doi.org/10.1023/b:urol.0000034654.26422.f7

Transplant renal artery kinking: a rare cause of early graft dysfunction

Mohiuddin Miah, Sanjeev Madaan, David J Kessel, Charles G Newstead and Sandeep Guleria 2004. Transplant renal artery kinking: a rare cause of early graft dysfunction. Nephrology Dialysis Transplantation. 19 (7). https://doi.org/10.1093/ndt/gfh152

5-years outcome of a prospective randomised trial to compare Transurethral Electrovaporization of the Prostate (TUVP) to Standard Transurethral Resection (TURP)

Mohamed Y. Hammadeh, Sanjeev Madaan, John Hines and Timothy Philp 2003. 5-years outcome of a prospective randomised trial to compare Transurethral Electrovaporization of the Prostate (TUVP) to Standard Transurethral Resection (TURP). Urology. 61 (6), pp. 1166-1171. https://doi.org/10.1016/S0090-4295(03)00109-2

Androgen-dependent regulation of human MUC1 mucin expression

Stephen Mitchell, Paul Abel, Sanjeev Madaan, James Jeffs, Khurram Chaudhary, Gordon Stamp and El-Nasir Lalani 2002. Androgen-dependent regulation of human MUC1 mucin expression. Neoplasia. 4 (1), pp. 9-18. https://doi.org/10.1038/sj.neo.7900194

Cyclooxygenase-2: a possible target in schistosoma-associated bladder cancer

S.S. El-Sheikh, S. Madaan, A. Alhasso, P. Abel, G. Stamp and E.-N. Lalani 2002. Cyclooxygenase-2: a possible target in schistosoma-associated bladder cancer. BJU International. 88 (9), pp. 921-927. https://doi.org/10.1046/j.1464-4096.2001.01649.x

Genitourinary neurofibromatosis with prostatic involvement

Madaan, S., Hammadeh, S., Thomas, K., Philp, T. and Singh, M. 2001. Genitourinary neurofibromatosis with prostatic involvement. BJU International. 87 (903).

Cytoplasmic induction and over-expression of cyclooxygenase-2 in human prostate cancer: implications for prevention and treatment

S. Madaan, P.D. Abel, K.S. Chaudhary, R. Hewitt, M.A. Stott, G.W.H. Stamp and E.-N. Lalani 2001. Cytoplasmic induction and over-expression of cyclooxygenase-2 in human prostate cancer: implications for prevention and treatment. BJU International. 86 (6), pp. 736-741. https://doi.org/1046/j.1464-410x.2000.00867.x

A 3-year follow-up of a prospective randomized trial comparing transurethral electrovaporization of the prostate with standard transurethral prostatectomy

Hammadeh, M. Y., Madaan, S., Singh, M. and Philp. T. 2001. A 3-year follow-up of a prospective randomized trial comparing transurethral electrovaporization of the prostate with standard transurethral prostatectomy. BJU International. 86 (6), pp. 648-651. https://doi.org/10.1046/j.1464-410x.2000.00879.x