Beauty from the deep: cnidarians in cosmetics

Book chapter


Trim, S.A., Wandrey, F and Trim, C.M. 2021. Beauty from the deep: cnidarians in cosmetics. in: Mariottini, G.L., Killi, N. and Xiao, L. (ed.) The Cnidaria: Only a problem or also a source Nova Science Publishers.
AuthorsTrim, S.A., Wandrey, F and Trim, C.M.
EditorsMariottini, G.L., Killi, N. and Xiao, L.
Abstract

Cnidarian proteins are considered useful for the development of therapeutics, as well as this they have also received the attention of biotechnology and the cosmetic industries. In 2017 the first ever sea anemone venom peptide cosmetic, named SensAmone P5, was launched by Mibelle Biochemistry. This synthetic peptide is based on the interaction of APHC1, from Heteractis crispa, on the pain relevant ion channel TRPV1. This peptide reduces TRPV1 signalling in-vitro and skin sensitivity in human volunteers. Aside from venoms, jellyfish mucus and collagen are both used in cosmetic preparations. Many legal definitions of animals do not include the invertebrates and thus it is likely that invertebrate proteins are more acceptable as an alternative to mammalian proteins. Mucins are important proteins for moisturisers and using jellyfish as the source appears to be a suitable alternative to bovine and porcine proteins which were previously used. The main structural protein that supports the soft bodied jellyfish is collagen. This collagen appears to be biocompatible with human tissues and thus has been successful as a cosmetic, as well as being used in-vitro for 3D tissue engineering scaffolds. This short communication will discuss the use of Cnidarian proteins in cosmetics.

KeywordsCnidarian ; Cosmetics; Biotechnology; Venom; TRPV1; Collagen; Jellyfish; Sea anemone; SensAmone P5
Year2021
Book titleThe Cnidaria: Only a problem or also a source
PublisherNova Science Publishers
Output statusIn press
File
Publication process dates
Accepted09 Dec 2020
Deposited04 Jan 2021
Permalink -

https://repository.canterbury.ac.uk/item/8wxz9/beauty-from-the-deep-cnidarians-in-cosmetics

  • 37
    total views
  • 65
    total downloads
  • 7
    views this month
  • 10
    downloads this month

Export as

Related outputs

Utilisation of compounds from venoms in drug discovery
Trim, C., Byrne, L. and Trim, S. 2021. Utilisation of compounds from venoms in drug discovery. in: Witty, D.R. (ed.) Progress in medicinal chemistry volume 60 Elsevier.
Powerful proteins from polyp possessing predators
Robinson P.J., Trim, S.A. and Trim, C.M. 2021. Powerful proteins from polyp possessing predators. in: Mariottini, G.L., Killi, N. and Xiao, L. (ed.) The Cnidaria: only a problem or also a source Nova Science Publishers.
Full spectrum lighting induces behavioral changes and increases cortisol immunoreactivity in captive arachnids
Somerville, S., Baker, S., Baines, F., Trim, S. and Trim, C.M. 2020. Full spectrum lighting induces behavioral changes and increases cortisol immunoreactivity in captive arachnids. Journal of Applied Animal Welfare Science. https://doi.org/10.1080/10888705.2021.1872027
The failures of ethnobotany and phytomedicine in delivering novel treatments for snakebite envenomation
Trim, S., Trim, C., Williams, H. F. and Vaiyapuri, S. 2020. The failures of ethnobotany and phytomedicine in delivering novel treatments for snakebite envenomation. Toxins. 12 (12). https://doi.org/10.3390/toxins12120774
Kinome scale profiling of venom effects on cancer cells reveals potential new venom activities
Mccullough, D., Atofanei, C., Knight, E., Trim, S. and Trim, C.M. 2020. Kinome scale profiling of venom effects on cancer cells reveals potential new venom activities. Toxicon. 185, pp. 129-146. https://doi.org/10.1016/j.toxicon.2020.07.007
Microbial adaptation to venom is common in snakes and spiders
Esmaeilishirazifard, E., Usher, L., Trim, C., Denise, H., Sangal, V., Tyson, G., Barlow, A., Redway, K., Taylor, J., Kremyda-Vlachou, M., Loftus, T., Lock, M., Wright, K., Dalby, A., Snyder, L., Wuster, W., Trim, S. and Moschos, S. 2018. Microbial adaptation to venom is common in snakes and spiders. bioRxiv. https://doi.org/10.1101/348433v1
Transitioning novel peptide hits into lead compounds
Trim, S. and Trim, C. 2019. Transitioning novel peptide hits into lead compounds. Drug Target Review. (4).
Non-invasive extraction of Cnidarian venom through the use of autotomised tentacles
Robinson, P., Trim, S. and Trim, C. 2019. Non-invasive extraction of Cnidarian venom through the use of autotomised tentacles. Animal Technology and Welfare. 18 (3).
Rapid method for targeted cell (line) selection
Lang, D., Martin, E., Montague, G., O'Malley, C., Root, T., Trim, C., Povey, J., Smales, C. and Racher, A. 2012. Rapid method for targeted cell (line) selection.
Localisation of Neuregulin 1-β3 to different sub-nuclear structures alters gene expression
Wang, M., Trim, C. and Gullick, W. 2011. Localisation of Neuregulin 1-β3 to different sub-nuclear structures alters gene expression. Experimental Cell Research. 317 (4), pp. 423-432. https://doi.org/10.1016/j.yexcr.2010.11.009.
Venom: The sharp end of pain therapy
Trim, S. and Trim, C. 2013. Venom: The sharp end of pain therapy. British Journal of Pain. 7 (4), pp. 179-188. https://doi.org/10.1177/2049463713502005
Novel approaches to targeting protein tyrosine kinases
McCullough, D. and Trim, C. 2015. Novel approaches to targeting protein tyrosine kinases. Drug Target Review.
Rapid high-throughput characterisation, classification and selection of recombinant mammalian cell line phenotypes using intact cell MALDI-ToF mass spectrometry fingerprinting and PLS-DA modelling
Povey, J., O'Malley, C., Root, T., Martin, E., Montague, G., Feary, M., Trim, C., Lang, D., Aldread, R., Racher, A. and Smales, C. 2014. Rapid high-throughput characterisation, classification and selection of recombinant mammalian cell line phenotypes using intact cell MALDI-ToF mass spectrometry fingerprinting and PLS-DA modelling. Journal of Biotechnology. 184, pp. 84-93. https://doi.org/10.1016/j.jbiotec.2014.04.028
Neuregulins in the nucleus
McClelland, C. and Gullick, W. 2009. Neuregulins in the nucleus. in: Giordano, A. and Normanno, N. (ed.) Breast Cancer In the Post-Genomic Era Springer. pp. 79-86
Proteomic identification of secreted proteins as surrogate markers for signal transduction inhibitor activity
McClelland, C. and Gullick, W. 2007. Proteomic identification of secreted proteins as surrogate markers for signal transduction inhibitor activity. British Journal of Cancer. 96 (2), pp. 284-289. https://doi.org/10.1038/sj.bjc.6603544
99mTc-SnF2 colloid “LLK”: particle size, morphology, and leukocyte labelling behaviour
McClelland, C., Onuegbulem, E., Carter, N., Leahy, M., O'Doherty, M., Pooley, F., O'Doherty, T., Newsam, R., Ensing, G. and Blower, P. 2003. 99mTc-SnF2 colloid “LLK”: particle size, morphology, and leukocyte labelling behaviour. Nuclear Medicine Communications. 24 (2), pp. 191-202. https://doi.org/10.1097/01.mnm.0000057333.59072.1c
Identification of surrogate markers for determining drug activity using proteomics
McClelland, C. and Gullick, W. 2003. Identification of surrogate markers for determining drug activity using proteomics. Biochemical Society Transactions. 31 (6), pp. 1488-1490. https://doi.org/10.1042/bst0311488