Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity

Journal article


Jaheer, H., Shetty, A., Choi, N., Kim, K., Thirumal, S., Song, J., Kim, K., Chun, Y. and Kim, S. 2019. Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity. Regenerative Therapy. 10, pp. 112-117. https://doi.org/10.1016/j.reth.2019.02.001
AuthorsJaheer, H., Shetty, A., Choi, N., Kim, K., Thirumal, S., Song, J., Kim, K., Chun, Y. and Kim, S.
Abstract

Purpose: High fibular osteotomy (HFO) is a simple surgical technique to reduce pain and improve function in patients with osteoarthritis via fibular osteotomy. We report short-term results of HFO and mesenchymal cell induced chondrogenesis (MCIC) for the treatment of osteoarthritis of knee with varus deformity.
Patients and methods: 45 symptomatic patients with 14 males and 31 females age ranging from 40 to 75
years were treated by HFO and MCIC. Main lesions involved medial compartment of knee and lateral
compartment with normal to mild lesions of lateral meniscus and articular cartilage, amenable to treatment via partial meniscectomy or observation.

Results: Knee injury and Osteoarthritis Outcome score and Lysholm showed a statistically significant increase and VAS, varus angle in X-ray showed a statistically significant decrease. A statistically significant difference between preoperative and postoperative scores was detected in male and female patients without any sexual differences.

Conclusion: High fibular osteotomy and mesenchymal cell induced chondrogenesis can be considered as a good treatment option for medial compartment osteoarthritis of knee with varus deformity.

KeywordsHigh fibular osteotomy; osteoarthritis; varus deformity; knee; mesenchymal cell induced chondrogenesis (MCIC)
Year2019
JournalRegenerative Therapy
Journal citation10, pp. 112-117
PublisherElsevier
ISSN2352-3204
Digital Object Identifier (DOI)https://doi.org/10.1016/j.reth.2019.02.001
Publication dates
Online22 Feb 2019
Publication process dates
Deposited19 Mar 2019
Accepted03 Feb 2019
Accepted author manuscript
Output statusPublished
Additional information

Open Access. Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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