Autologous bone-marrow mesenchymal cell induced chondrogenesis (MCIC)

Journal article


Huh, S., Shetty, A., Ahmed, S., Lee, D. and Kim, S. 2016. Autologous bone-marrow mesenchymal cell induced chondrogenesis (MCIC). Journal of Clinical Orthopaedics and Trauma. 7 (3), pp. 153-156. https://doi.org/10.1016/j.jcot.2016.05.004
AuthorsHuh, S., Shetty, A., Ahmed, S., Lee, D. and Kim, S.
Abstract

Degenerative and traumatic articular cartilage defects are common, difficult to treat, and progressive lesions that cause significant morbidity in the general population. There have been multiple approaches to treat such lesions, including arthroscopic debridement, microfracture, multiple drilling, osteochondral transplantation and autologous chondrocyte implantation (ACI) that are currently being used in clinical practice. Autologous bone-marrow mesenchymal cell induced chondrogenesis (MCIC) is a single-
staged arthroscopic procedure. This method combines a modified microfracture technique with theapplication of a bone marrow aspirate concentrate (BMAC), hyaluronic acid and fibrin gel to treat
articular cartilage defects. We reviewed the current literatures and surgical techniques for mesenchymal cell induced chondrogenesis.

KeywordsKnee arthroscopy; cartilage; chondral defect; arthrosis; bone marrow aspirate concentrate
Year2016
JournalJournal of Clinical Orthopaedics and Trauma
Journal citation7 (3), pp. 153-156
PublisherElsevier
ISSN0976-5662
Digital Object Identifier (DOI)https://doi.org/10.1016/j.jcot.2016.05.004
Publication dates
Online16 Jun 2016
Publication process dates
Deposited19 Mar 2019
Accepted11 May 2016
Output statusPublished
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https://repository.canterbury.ac.uk/item/88z11/autologous-bone-marrow-mesenchymal-cell-induced-chondrogenesis-mcic

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